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This cohort study set in a tertiary hospital in Uganda investigated the long-term outcomes of children with DTCAs. Caregivers with deceased children completed a verbal autopsy, while those with live children completed a PedsQL quality of life (QoL) survey. Multivariate Cox proportional hazard regression and linear regression explored factors associated with death and quality of life, respectively. Of the 362 participating caregivers, 265 (73.2%) had a child with a DTCA who survived since hospital discharge. The median age and follow-up time were 3.2\u2009years. The mortality hazard ratio for children with DTCAs was 2.70 (95% confidence interval\u20092.21-3.30). Mortality was associated with DTCA diagnosis, the presence of stoma, and higher household income. 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