{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T21:03:05Z","timestamp":1780002185815,"version":"3.53.1"},"reference-count":8,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Sage Open Pediatrics"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:p>Neonatal Cholestasis is one of the rare yet important causes of Vitamin K deficiency bleeding (VKDB) in infants. VKDB may present as Gastro Intestinal (GI) bleeding and in severe cases as Intracranial hemorrhage. We report a case of a 42 days old, previously healthy, male infant presenting with seizures and GI bleeding. Laboratory investigations revealed direct hyperbilirubinemia and markedly elevated PT\/INR. These findings were consistent with neonatal cholestasis and Vitamin K deficiency. Cranial and Abdominal Ultrasonography were normal. The seizure was managed with Vit K and Fresh Frozen Plasma following which his coagulation profile and clinical status improved. Although intracranial hemorrhage could not be confirmed radiologically, this case highlights the importance of considering vitamin K deficiency and underlying hepatobiliary pathology in infants presenting with bleeding manifestations and seizures. Early recognition and treatment are essential to prevent life-threatening complications.<\/jats:p>","DOI":"10.1177\/30502225261456572","type":"journal-article","created":{"date-parts":[[2026,5,25]],"date-time":"2026-05-25T13:27:54Z","timestamp":1779715674000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Neonatal Cholestasis Presenting With Seizures Associated With Vitamin K Deficiency: A Case Report"],"prefix":"10.1177","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1555-4121","authenticated-orcid":false,"given":"Bipesh Kumar","family":"Shah","sequence":"first","affiliation":[{"name":"B.P Koirala Institute of Health Sciences"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-7271-6058","authenticated-orcid":false,"given":"Smita","family":"Paudel","sequence":"additional","affiliation":[{"name":"B.P Koirala Institute of Health Sciences"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,5,25]]},"reference":[{"key":"e_1_3_7_2_2","doi-asserted-by":"publisher","DOI":"10.21037\/tp-21-503"},{"key":"e_1_3_7_3_2","doi-asserted-by":"publisher","DOI":"10.1542\/neo.22-12-e819"},{"key":"e_1_3_7_4_2","doi-asserted-by":"publisher","DOI":"10.3390\/nu12030780"},{"key":"e_1_3_7_5_2","doi-asserted-by":"publisher","DOI":"10.3390\/nu15112491"},{"key":"e_1_3_7_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2016.03.035"},{"key":"e_1_3_7_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jped.2020.09.003"},{"key":"e_1_3_7_8_2","doi-asserted-by":"publisher","DOI":"10.4084\/MJHID.2013.049"},{"key":"e_1_3_7_9_2","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.73732"}],"container-title":["Sage Open Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/30502225261456572","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/30502225261456572","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/30502225261456572","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T20:16:28Z","timestamp":1779999388000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/30502225261456572"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3]]},"references-count":8,"alternative-id":["10.1177\/30502225261456572"],"URL":"https:\/\/doi.org\/10.1177\/30502225261456572","relation":{},"ISSN":["3050-2225","3050-2225"],"issn-type":[{"value":"3050-2225","type":"print"},{"value":"3050-2225","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3]]},"article-number":"30502225261456572"}}