{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T11:12:52Z","timestamp":1783681972712,"version":"3.55.0"},"reference-count":38,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"The European Union \u2013 NextGenerationEU","award":["BG-RRP-2.013-0001"],"award-info":[{"award-number":["BG-RRP-2.013-0001"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Sage Open Pediatrics"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Early childhood development is shaped by interactions between biological, prenatal, nutritional, and social factors. Evidence regarding their domain-specific associations across ASQ-3 domains remains limited in Eastern Europe.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To examine biological, prenatal, nutritional, and social predictors of developmental outcomes measured with the ASQ-3.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This cross-sectional study included 167 full-term Bulgarian children aged 14\u201342 months. Parents completed age-appropriate ASQ-3 questionnaires and a structured survey on prenatal and family characteristics. Raw ASQ-3 scores were converted into age-standardized Z-scores. Stepwise multiple linear regression analyses were conducted for each domain.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Longer breastfeeding duration was positively associated with communication, fine motor, and problem-solving outcomes. Prenatal tobacco exposure was associated with lower communication, fine motor, and problem-solving scores. Communication outcomes were additionally associated with residential setting and bilingual home environment. No significant predictors were identified for gross motor development.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Early developmental domains demonstrate distinct associations with prenatal, nutritional, and social factors.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/30502225261464725","type":"journal-article","created":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T05:39:12Z","timestamp":1783489152000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Determinants of Early Child Development"],"prefix":"10.1177","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9074-8511","authenticated-orcid":false,"given":"Tatyana","family":"Itova","sequence":"first","affiliation":[{"name":"University Multidisciplinary Hospital \u201cMEDICA Ruse\u201d Ltd"},{"name":"University of Ruse \u201cAngel Kanchev\u201d"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,7,7]]},"reference":[{"key":"e_1_3_7_2_2","doi-asserted-by":"publisher","DOI":"10.3389\/fpubh.2024.1301524"},{"key":"e_1_3_7_3_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12887-024-05112-3"},{"key":"e_1_3_7_4_2","doi-asserted-by":"publisher","DOI":"10.4102\/jphia.v16i1.822"},{"key":"e_1_3_7_5_2","doi-asserted-by":"publisher","DOI":"10.1177\/1476718X211020031"},{"key":"e_1_3_7_6_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2025.1540"},{"key":"e_1_3_7_7_2","doi-asserted-by":"publisher","DOI":"10.1017\/S1047951124025228"},{"key":"e_1_3_7_8_2","doi-asserted-by":"publisher","DOI":"10.1007\/s13158-024-00396-z"},{"key":"e_1_3_7_9_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2025-071516"},{"key":"e_1_3_7_10_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-024-51263-9"},{"key":"e_1_3_7_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/icd.2331"},{"key":"e_1_3_7_12_2","doi-asserted-by":"publisher","DOI":"10.18332\/tid\/202349"},{"key":"e_1_3_7_13_2","doi-asserted-by":"publisher","DOI":"10.1111\/apa.70285"},{"key":"e_1_3_7_14_2","doi-asserted-by":"publisher","DOI":"10.21203\/rs.3.rs-4283363"},{"key":"e_1_3_7_15_2","volume-title":"ASQ-3: Ages & Stages Questionnaires\u00ae, Third Edition","author":"Squires J","year":"2009","unstructured":"Squires J, Bricker D, Twombly E. 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