{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T08:51:12Z","timestamp":1777884672142,"version":"3.51.4"},"reference-count":10,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2025,9,9]],"date-time":"2025-09-09T00:00:00Z","timestamp":1757376000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Pharmacy Technology"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:p>\n                    <jats:bold>Background:<\/jats:bold>\n                    The 2021 Centers of Disease Control and Prevention (CDC) sexually transmitted infection treatment guidelines recommend a 7-day course of metronidazole or single-dose tinidazole for women with trichomoniasis due to improved patient outcomes compared with single-dose metronidazole therapy. A health system antimicrobial stewardship program implemented an interruptive electronic health record (EHR) alert to promote optimal trichomoniasis prescribing when nonrecommended treatment is ordered.\n                    <jats:bold>Objective:<\/jats:bold>\n                    To determine the impact of an interruptive EHR alert on optimal trichomoniasis prescribing for women.\n                    <jats:bold>Methods:<\/jats:bold>\n                    This was an institutional review board\u2013approved, single pretest, posttest quasi-experiment of women \u226515 years with a microbiologically confirmed\n                    <jats:italic toggle=\"yes\">Trichomonas vaginalis<\/jats:italic>\n                    infection from 10\/2023 to 12\/2023 (preintervention) and 10\/2024 to 12\/2024 (postintervention). An EHR alert was implemented 9\/2024 that notifies prescribers that single-dose metronidazole 2 g is not recommended and suggests CDC-recommended treatments. The primary outcome was the proportion of single-dose metronidazole 2 g orders before and after EHR alert implementation. A secondary cross-sectional evaluation of all alerts triggered from 10\/2024 to 12\/2024 was performed and included the number of alerts, location of alert, and provider response.\n                    <jats:bold>Results:<\/jats:bold>\n                    A total of 285 patients were included, 49.8% pre-intervention and 50.2% postintervention. Metronidazole 2 g was prescribed for 8.45% of pre-intervention and 2.80% of postintervention patients (\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    = 0.038). The clinical support alert fired 102 times for 75 patients during the 3-month postimplementation period. The alert was associated with a change in intended prescription to a metronidazole 7-day course in greater than 60% of patients over 3 months.\n                    <jats:bold>Conclusion:<\/jats:bold>\n                    The implementation of an interruptive alert was associated with high acceptance and improved prescribing for women treated for trichomoniasis.\n                  <\/jats:p>","DOI":"10.1177\/87551225251369348","type":"journal-article","created":{"date-parts":[[2025,9,9]],"date-time":"2025-09-09T11:54:41Z","timestamp":1757418881000},"page":"63-68","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Impact of an Interruptive Alert on the Number of Women Receiving CDC-Recommended Therapy for Trichomoniasis"],"prefix":"10.1177","volume":"42","author":[{"given":"Nicole","family":"Sunshine","sequence":"first","affiliation":[{"name":"Henry Ford Health, Detroit, MI, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rachel M.","family":"Kenney","sequence":"additional","affiliation":[{"name":"Henry Ford Health, Detroit, MI, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8000-8453","authenticated-orcid":false,"given":"Nathan A.","family":"Everson","sequence":"additional","affiliation":[{"name":"Henry Ford Health, Detroit, MI, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christen J.","family":"Arena","sequence":"additional","affiliation":[{"name":"Henry Ford Health, Detroit, MI, USA"},{"name":"Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erin","family":"Eriksson","sequence":"additional","affiliation":[{"name":"Henry Ford Health, Detroit, MI, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brian M.","family":"Church","sequence":"additional","affiliation":[{"name":"Henry Ford Health, Detroit, MI, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacob","family":"Manteuffel","sequence":"additional","affiliation":[{"name":"Henry Ford Health, Detroit, MI, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5967-5211","authenticated-orcid":false,"given":"Michael P.","family":"Veve","sequence":"additional","affiliation":[{"name":"Henry Ford Health, Detroit, MI, USA"},{"name":"Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,9,9]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.rr7004a1"},{"issue":"33","key":"e_1_3_2_3_2","first-page":"1","article-title":"Sexually transmitted diseases treatment guidelines, 2015","volume":"64","author":"Workowski KA","year":"2015","unstructured":"Workowski KA, Bolan GA; Centers for Disease Control and Prevention. Sexually transmitted diseases treatment guidelines, 2015 [published correction appears in MMWR Recomm Rep. 2015;64(33):924]. MMWR Recomm Rep. 2015;64(RR-03):1-137.","journal-title":"MMWR Recomm Rep"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(18)30423-7"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1097\/OLQ.0000000000001987"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.297.4.403"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1093\/jamiaopen\/ooad056"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2023-080546"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1017\/ash.2024.448"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1093\/jamia\/ocaa034"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1017\/ice.2021.397"}],"container-title":["Journal of Pharmacy Technology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/87551225251369348","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/87551225251369348","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/87551225251369348","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T02:33:32Z","timestamp":1777602812000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/87551225251369348"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9,9]]},"references-count":10,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,4]]}},"alternative-id":["10.1177\/87551225251369348"],"URL":"https:\/\/doi.org\/10.1177\/87551225251369348","relation":{},"ISSN":["8755-1225","1549-4810"],"issn-type":[{"value":"8755-1225","type":"print"},{"value":"1549-4810","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,9,9]]}}}