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Ankle-brachial index and carotid ultrasound were performed in all participants. Generalized additive multivariable models were used to adjust a regression model of common carotid IMT on ABI. Logistic regression multivariable models were adjusted to assess the probability of carotid plaque in individuals with peripheral artery disease. We included 3307 individuals (54.2% women), mean age 60 years (standard deviation 11). Two patterns of association were observed between subclinical biomarkers of atherosclerosis at the lower limb and carotid artery. Ankle-brachial index and common carotid IMT showed a linear trend in men [beta coefficient (95% confidence interval) =-.068 (\u2212.123; \u2212.012); P = .016]. Women with peripheral artery disease presented with high risk of atherosclerotic plaque at the carotid artery [Odds ratio (95% confidence interval) = 2.61, (1.46; 4.69); P = .001]. Men showed a significant linear association between ABI levels and common carotid IMT values. Women with peripheral artery disease presented with high risk of atherosclerotic plaque at the carotid artery.<\/jats:p>","DOI":"10.1177\/00033197221110720","type":"journal-article","created":{"date-parts":[[2022,6,25]],"date-time":"2022-06-25T08:50:29Z","timestamp":1656147029000},"page":"443-451","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Polyvascular Subclinical Atherosclerosis: Correlation Between Ankle Brachial Index and Carotid Atherosclerosis in a Population-Based Sample"],"prefix":"10.1177","volume":"74","author":[{"given":"Maria del Mar","family":"Vila","sequence":"first","affiliation":[{"name":"Consortium for Biomedical Research - Cardiovascular Diseases (CIBERCV), Barcelona, Spain"},{"name":"IMIM - Hospital del Mar Health Research Institute, Barcelona, Spain"},{"name":"Department of Mathematics and Computer Science, University of Barcelona, Spain"}]},{"given":"Laura","family":"Igual","sequence":"additional","affiliation":[{"name":"Department of Mathematics and Computer Science, University of Barcelona, Spain"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9265-253X","authenticated-orcid":false,"given":"Beatriz","family":"Remeseiro","sequence":"additional","affiliation":[{"name":"Department of Computer Science, University of Oviedo, Gij\u00f3n, Spain"}]},{"given":"Roberto","family":"Elosua","sequence":"additional","affiliation":[{"name":"Consortium for Biomedical Research - Cardiovascular Diseases (CIBERCV), Barcelona, Spain"},{"name":"IMIM - Hospital del Mar Health Research Institute, Barcelona, Spain"},{"name":"Faculty of Medicine, University of Vic \u2013 Central University of Catalunya, Vic, Spain"}]},{"given":"Rafel","family":"Ramos","sequence":"additional","affiliation":[{"name":"University Institute for Primary Health Care Research Jordi Gol (IDIAP Jordi Gol), Girona, Spain"},{"name":"Vascular Health Research Group, Research Unit in Primary Care, Catalan Institute of Health, Girona, Spain"},{"name":"Girona Biomedical Research Institute (IdIBGi), Girona, Spain"},{"name":"Department of Medical Sciences, School of Medicine, University of Girona, Spain"}]},{"given":"Jose M","family":"Valdivielso","sequence":"additional","affiliation":[{"name":"Vascular and Renal Translational Research Group and Unit for Detection and Treatment of Cardiovascular Diseases (UDETMA). Biomedical Research Institute (IRBLleida), Lleida, Spain"}]},{"given":"Ruth","family":"Mart\u00ed-Lluch","sequence":"additional","affiliation":[{"name":"University Institute for Primary Health Care Research Jordi Gol (IDIAP Jordi Gol), Girona, Spain"},{"name":"Vascular Health Research Group, Research Unit in Primary Care, Catalan Institute of Health, Girona, Spain"}]},{"given":"Jaume","family":"Marrugat","sequence":"additional","affiliation":[{"name":"Consortium for Biomedical Research - Cardiovascular Diseases (CIBERCV), Barcelona, Spain"},{"name":"IMIM - Hospital del Mar Health Research Institute, Barcelona, Spain"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2807-8136","authenticated-orcid":false,"given":"Maria","family":"Grau","sequence":"additional","affiliation":[{"name":"IMIM - Hospital del Mar Health Research Institute, Barcelona, Spain"},{"name":"Serra-Hunter Fellow, Department of Medicine, School of Medicine and Health Sciences, University of Barcelona, Barcelona, 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