{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T13:21:46Z","timestamp":1777900906791,"version":"3.51.4"},"reference-count":13,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[1971,3,1]],"date-time":"1971-03-01T00:00:00Z","timestamp":36633600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Scott Med J"],"published-print":{"date-parts":[[1971,3]]},"abstract":"<jats:p>Crohn's disease is increasing in frequency, mainly in urban areas. Small bowel disease is 4 times more common than transmural inflammation of the large bowel. A history of colicky abdominal pain, diarrhoea and weight loss should always arouse the suspicion of Crohn's disease, especially when the patient is a young woman. In more than half the patients no mass can be felt. Large bowel disease is relatively commoner in older patients. Crohn's disease must be considered in the differential diagnosis of gynaecological complaints, and may cause symptoms referrable to the spine and hip joints. Barium enema is the most useful confirmatory investigation provided reflux into the terminal ileum is obtained.<\/jats:p>","DOI":"10.1177\/003693307101600304","type":"journal-article","created":{"date-parts":[[2017,1,11]],"date-time":"2017-01-11T00:29:36Z","timestamp":1484094576000},"page":"197-201","source":"Crossref","is-referenced-by-count":9,"title":["The Early Diagnosis of Chronic Crohn's Disease"],"prefix":"10.1177","volume":"16","author":[{"given":"James","family":"Kyle","sequence":"first","affiliation":[{"name":"Gastroenterology Research Unit, Royal Infirmary, Aberdeen"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1971,3,1]]},"reference":[{"key":"bibr1-003693307101600304","volume-title":"Pathological and practical researches on diseases of the stomach, the intestinal canal, the liver and other viscera of the abdomen","author":"Abercrombie J.","year":"1828"},{"key":"bibr2-003693307101600304","first-page":"16","volume":"4","author":"Combe C.","year":"1813","journal-title":"Medical Transactions of the College of Physicians in London"},{"key":"bibr3-003693307101600304","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1932.02740680019005"},{"key":"bibr4-003693307101600304","first-page":"1068","volume":"2","author":"Dalziel T. 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