{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T12:17:48Z","timestamp":1758629868785,"version":"3.38.0"},"reference-count":35,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2018,9,21]],"date-time":"2018-09-21T00:00:00Z","timestamp":1537488000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["309717\/2014-0"],"award-info":[{"award-number":["309717\/2014-0"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Cons\u00f3rcio CAPES\/Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia","award":["FCT\/CAPES:10172\/13-0"],"award-info":[{"award-number":["FCT\/CAPES:10172\/13-0"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Ultrason Imaging"],"published-print":{"date-parts":[[2019,1]]},"abstract":"<jats:p> We describe the concept of a new imaging modality based on the tracking and dynamic modeling of local intensity changes (ICs) observed in conventional ultrasound images collected during a medium-temperature change. We computed the pixel-by-pixel IC from averaged B-mode images that exhibited different behaviors with varying temperature resulting from changes in the speed of sound, which consequently induce changes in the backscattered energy. Moreover, for each pixel, a first-order polynomial model was adjusted to the different temperature-dependent ICs. The representation of the polynomial angular parameter in 2D pixel space was used to obtain a parametric image. The results obtained by simulations and with real B-mode images indicated that this new ultrasound imaging modality was able to enhance the contrast and highlight structures that were poorly visible or even undetected in conventional images. A temperature change of 3\u00b0C was found to be sufficient to generate appropriate images with the proposed method. In addition, if a temperature change of 6\u00b0C was considered, the thermal dose, measured as the cumulative number of equivalent minutes at 43\u00b0C (CEM43\u00b0C), was 2.4 CEM43\u00b0C, which is a value that is considered safe according to the literature. We provide a proof-of-concept of a new imaging modality that opens new opportunities for the enhancement of ultrasound images and consequently contributes to improvements in ultrasound-based diagnoses. Our approach is based on images returned by commercial ultrasound scanners. Therefore, it can be implemented in any ultrasound system and is independent of specific ultrasound hardware and software data acquisition characteristics. <\/jats:p>","DOI":"10.1177\/0161734618800660","type":"journal-article","created":{"date-parts":[[2018,9,21]],"date-time":"2018-09-21T15:32:08Z","timestamp":1537543928000},"page":"17-34","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["On the Feasibility of Ultrasound Imaging Enrichment by Medium-Temperature Changes"],"prefix":"10.1177","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9396-1211","authenticated-orcid":false,"given":"C. A.","family":"Teixeira","sequence":"first","affiliation":[{"name":"Department of Informatics Engineering, Centre for Informatics and Systems (CISUC), University of Coimbra, Coimbra, Portugal"}]},{"given":"M.","family":"Pastrana-Chalco","sequence":"additional","affiliation":[{"name":"Department of Informatics Engineering, Centre for Informatics and Systems (CISUC), University of Coimbra, Coimbra, Portugal"},{"name":"Biomedical Engineering Program, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil"}]},{"given":"R. J.","family":"Sim\u00f5es","sequence":"additional","affiliation":[{"name":"Department of Informatics Engineering, Centre for Informatics and Systems (CISUC), University of Coimbra, Coimbra, Portugal"}]},{"given":"A.","family":"Pedrosa","sequence":"additional","affiliation":[{"name":"Department of Informatics Engineering, Centre for Informatics and Systems (CISUC), University of Coimbra, Coimbra, Portugal"}]},{"given":"M. A.","family":"von Kr\u00fcger","sequence":"additional","affiliation":[{"name":"Biomedical Engineering Program, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil"}]},{"given":"A. V.","family":"Alvarenga","sequence":"additional","affiliation":[{"name":"Laboratory of Ultrasound, National Institute of Metrology, Quality and Technology (Inmetro), Rio de Janeiro, Brazil"}]},{"given":"A. J.","family":"Fontes-Pereira","sequence":"additional","affiliation":[{"name":"Biomedical Engineering Program, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil"}]},{"given":"W. C. A.","family":"Pereira","sequence":"additional","affiliation":[{"name":"Biomedical Engineering Program, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil"}]}],"member":"179","published-online":{"date-parts":[[2018,9,21]]},"reference":[{"unstructured":"WHO Study Group. Training in diagnostic ultrasound: essentials, principles and standards. Report of a WHO Study Group. World Health Organ Tech Rep Ser. 1998;875:i-46; back cover. Available from http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/9659004.","key":"bibr1-0161734618800660"},{"doi-asserted-by":"publisher","key":"bibr2-0161734618800660","DOI":"10.1016\/B978-1-4160-3264-9.50005-7"},{"doi-asserted-by":"crossref","unstructured":"Belohlavek M, Foley DA, Gerber TC, Kinter TM, Greenleaf JF, Seward JB. Three- and four-dimensional cardiovascular ultrasound imaging: a new era for echocardiography. Mayo Clin Proc. 1993;68(3):221-40. Available from: http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/8474264.","key":"bibr3-0161734618800660","DOI":"10.1016\/S0025-6196(12)60042-1"},{"doi-asserted-by":"crossref","unstructured":"Fledelius HC. Ultrasound in ophthalmology. Ultrasound Med Biol. 1997;23(3):365-75. Available from: http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/9160904.","key":"bibr4-0161734618800660","DOI":"10.1016\/S0301-5629(96)00213-X"},{"doi-asserted-by":"publisher","key":"bibr5-0161734618800660","DOI":"10.1177\/016173469101300201"},{"doi-asserted-by":"crossref","unstructured":"Xu M, Wang LV. Photoacoustic imaging in biomedicine. Rev Sci Instrum. 2006;77(4):041101. Available from: http:\/\/aip.scitation.org\/doi\/10.1063\/1.2195024","key":"bibr6-0161734618800660","DOI":"10.1063\/1.2195024"},{"doi-asserted-by":"crossref","unstructured":"Li X, Yu K, He B. Magnetoacoustic tomography with magnetic induction (MAT-MI) for imaging electrical conductivity of biological tissue: a tutorial review. Phys Med Biol. 2016;61(18):R249-70. Available from: http:\/\/stacks.iop.org\/0031-9155\/61\/i=18\/a=R249?key=crossref.db169d0ffee90cd21cd2efb24ac3e02e.","key":"bibr7-0161734618800660","DOI":"10.1088\/0031-9155\/61\/18\/R249"},{"doi-asserted-by":"publisher","key":"bibr8-0161734618800660","DOI":"10.1038\/nature16066"},{"doi-asserted-by":"publisher","key":"bibr9-0161734618800660","DOI":"10.1109\/TMI.2014.2359650"},{"doi-asserted-by":"publisher","key":"bibr10-0161734618800660","DOI":"10.1016\/S0301-5629(01)00495-1"},{"doi-asserted-by":"publisher","key":"bibr11-0161734618800660","DOI":"10.1016\/S1361-8415(00)00039-6"},{"doi-asserted-by":"publisher","key":"bibr12-0161734618800660","DOI":"10.1109\/58.710592"},{"doi-asserted-by":"publisher","key":"bibr13-0161734618800660","DOI":"10.1016\/j.ultrasmedbio.2008.02.004"},{"doi-asserted-by":"publisher","key":"bibr14-0161734618800660","DOI":"10.1109\/10.398644"},{"issue":"2","key":"bibr15-0161734618800660","volume":"52","author":"Amini AN","year":"2005","journal-title":"IEEE Trans Biomed Eng"},{"doi-asserted-by":"publisher","key":"bibr16-0161734618800660","DOI":"10.1016\/0301-5629(94)90051-5"},{"doi-asserted-by":"publisher","key":"bibr17-0161734618800660","DOI":"10.1118\/1.1570373"},{"doi-asserted-by":"publisher","key":"bibr18-0161734618800660","DOI":"10.1121\/1.4800356"},{"doi-asserted-by":"publisher","key":"bibr19-0161734618800660","DOI":"10.1016\/j.ultras.2014.02.021"},{"doi-asserted-by":"publisher","key":"bibr20-0161734618800660","DOI":"10.1109\/TUFFC.2005.1561620"},{"doi-asserted-by":"publisher","key":"bibr21-0161734618800660","DOI":"10.1121\/1.1913479"},{"doi-asserted-by":"crossref","unstructured":"Treeby BE Cox BT. k-Wave: MATLAB toolbox for the simulation and reconstruction of photoacoustic wave fields. J Biomed Opt. 2010;15(2):021314. Available from: http:\/\/biomedicaloptics.spiedigitallibrary.org\/article.aspx?doi=10.1117\/1.3360308.","key":"bibr22-0161734618800660","DOI":"10.1117\/1.3360308"},{"doi-asserted-by":"crossref","unstructured":"Azhari H. Basics of Biomedical Ultrasound for Engineers [Internet]. Basics of Biomedical Ultrasound for Engineers. Hoboken, NJ, USA: John Wiley & Sons, Inc.; 2010. Available from: http:\/\/doi.wiley.com\/10.1002\/9780470561478.","key":"bibr23-0161734618800660","DOI":"10.1002\/9780470561478"},{"unstructured":"CamStudio.org. CamStudio. Available from: http:\/\/camstudio.org.","key":"bibr24-0161734618800660"},{"unstructured":"LICENSE GNUGP. GNU General Public License. Distribution. 1989;(June):1-9. Available from: https:\/\/www.gnu.org\/licenses\/licenses.html#GPL.","key":"bibr25-0161734618800660"},{"doi-asserted-by":"publisher","key":"bibr26-0161734618800660","DOI":"10.1016\/0301-5629(79)90084-X"},{"doi-asserted-by":"publisher","key":"bibr27-0161734618800660","DOI":"10.1016\/S0301-5629(96)00150-0"},{"doi-asserted-by":"publisher","key":"bibr28-0161734618800660","DOI":"10.1109\/TIP.2003.819861"},{"doi-asserted-by":"publisher","key":"bibr29-0161734618800660","DOI":"10.1016\/j.ultras.2012.03.001"},{"doi-asserted-by":"publisher","key":"bibr30-0161734618800660","DOI":"10.1016\/j.ultrasmedbio.2004.07.021"},{"volume-title":"BiOS\u201998 International Biomedical Optics Symposium","author":"Simon C","key":"bibr31-0161734618800660"},{"doi-asserted-by":"crossref","unstructured":"Alvarenga AV, Teixeira CA, Ruano MG, Pereira WCA. Influence of temperature variations on the entropy and correlation of the Grey-Level Co-occurrence Matrix from B-Mode images. Ultrasonics. 2010;50(2):290-3. Available from: http:\/\/www.sciencedirect.com\/science\/article\/pii\/S0041624X09001036.","key":"bibr32-0161734618800660","DOI":"10.1016\/j.ultras.2009.09.002"},{"doi-asserted-by":"publisher","key":"bibr33-0161734618800660","DOI":"10.1148\/radiol.2392041315"},{"doi-asserted-by":"publisher","key":"bibr34-0161734618800660","DOI":"10.1007\/s00330-013-2825-y"},{"unstructured":"WHO. Cardiovascular diseases (CVDs). 2015. Available from: www.who.int\/mediacenter\/factsheets\/fs317en\/.","key":"bibr35-0161734618800660"}],"container-title":["Ultrasonic Imaging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0161734618800660","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0161734618800660","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0161734618800660","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T21:29:23Z","timestamp":1740864563000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0161734618800660"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,9,21]]},"references-count":35,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,1]]}},"alternative-id":["10.1177\/0161734618800660"],"URL":"https:\/\/doi.org\/10.1177\/0161734618800660","relation":{},"ISSN":["0161-7346","1096-0910"],"issn-type":[{"type":"print","value":"0161-7346"},{"type":"electronic","value":"1096-0910"}],"subject":[],"published":{"date-parts":[[2018,9,21]]}}}