{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,3,2]],"date-time":"2025-03-02T05:48:47Z","timestamp":1740894527759,"version":"3.38.0"},"reference-count":47,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2020,7,14]],"date-time":"2020-07-14T00:00:00Z","timestamp":1594684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Med Biogr"],"published-print":{"date-parts":[[2022,2]]},"abstract":"<jats:p> In 1900 research on cutaneous sensation was defined by histological techniques defining sensory receptors in skin, leading to undetermined conceptual problems when considered in relation to Brown-S\u00e9quard\u2019s startling finding that there were two qualitatively different afferent pathways in the spinal cord. Four modalities were considered to function as the determinants of sensory input. In 1903 Rivers and Head carried out the first interventional study of human cutaneous sensation, and analysed the return of sensation following section and immediate suture of the dorsal cutaneous branch of Head\u2019s left radial nerve. This resulted in the revolutionary idea summarised in his description of protopathic and epicritic sensory systems in peripheral sensory nerve. Although this concept was at best seen as controversial and even ridiculed by some of his many contemporaneous critics, more recently this concept has proven a fundamentally important stimulus to understanding the physiology of cutaneous sensation. His writings show him to have been capable of deeply instructive thought, based on his clinical experience and his admiration of Hughlings Jackson\u2019s teaching concerning the hierarchical organisation of brain function. First and foremost a clinician neuroscientist, his ideas were ahead of their time and not understood. <\/jats:p>","DOI":"10.1177\/0967772020940553","type":"journal-article","created":{"date-parts":[[2020,7,15]],"date-time":"2020-07-15T06:28:05Z","timestamp":1594794485000},"page":"57-63","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Henry Head\u2019s lifelong studies of cutaneous sensation"],"prefix":"10.1177","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8717-8914","authenticated-orcid":false,"given":"Michael","family":"Swash","sequence":"first","affiliation":[{"name":"Department of Neurology, Royal London Hospital, London, UK"},{"name":"Barts and the London School of Medicine, Queen Mary University of London, London, UK"},{"name":"The Royal London Hospital, Barts Health NHS Trust, London, UK"},{"name":"Faculdade de Medicina, Instituto de Fisiologia, Instituto de Medicina Molecular Jo\u00e3o Lobo Antunes, Universidade de Lisboa, Lisbon, Portugal"}]}],"member":"179","published-online":{"date-parts":[[2020,7,14]]},"reference":[{"doi-asserted-by":"publisher","key":"bibr1-0967772020940553","DOI":"10.1093\/brain\/41.3-4.344"},{"key":"bibr2-0967772020940553","first-page":"192","volume":"1","author":"Brown-S\u00e9quard C-E.","year":"1849","journal-title":"C R Soc Biol (Paris)"},{"key":"bibr3-0967772020940553","first-page":"70","volume":"31","author":"Brown-S\u00e9quard C-E.","year":"1850","journal-title":"C R Acad Sci"},{"key":"bibr4-0967772020940553","first-page":"282","volume":"46","author":"Von Frey M","year":"1894","journal-title":"Berichte \u00fcber die Verhandlungen der K\u00f6niglich S\u00e4chsischen Gesellschaft der Wissenschaften"},{"doi-asserted-by":"publisher","key":"bibr5-0967772020940553","DOI":"10.1113\/expphysiol.1916.sp000216"},{"unstructured":"Volkmann AV. 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