{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T10:02:32Z","timestamp":1777716152577,"version":"3.51.4"},"reference-count":32,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2002,4,1]],"date-time":"2002-04-01T00:00:00Z","timestamp":1017619200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J Surg Pathol"],"published-print":{"date-parts":[[2002,4]]},"abstract":"<jats:p>We evaluated the clinicopathologic, immunohistochemical, lectin histochemical, ultrastructural and morphometric characteristics of a series of 28 poorly differentiated carcinomas of the thyroid (PDCT). The 28 tumors were classified according to their predominant growth pattern as insular (n=12), trabecular (n=10) and solid subtypes (n=6). The overall mortality rate was 46%. No significant differences were found among the 3 subtypes. Data obtained by lectin histochemistry, electron microscopy, and morphometry point to a closer relationship of PDCT to follicular than to papillary carcinoma. Our results do not support the subdivision of PDCT into subtypes.<\/jats:p>","DOI":"10.1177\/106689690201000205","type":"journal-article","created":{"date-parts":[[2007,6,21]],"date-time":"2007-06-21T21:50:28Z","timestamp":1182462628000},"page":"123-131","source":"Crossref","is-referenced-by-count":55,"title":["Poorly Differentiated Carcinomas of the Thyroid Gland"],"prefix":"10.1177","volume":"10","author":[{"given":"Manuel","family":"Sobrinho-Simoes","sequence":"first","affiliation":[]},{"given":"Clara","family":"Sambade","sequence":"additional","affiliation":[]},{"given":"Elsa","family":"Fonseca","sequence":"additional","affiliation":[{"name":"Institute of Molecular Pathology and Immunology of the University ofPorto-IPATIMUP, Porto, Portugal; Department of Pathology, Medical Faculty of Porto, Porto, Portugal; Department of Pathology, Hospital S. 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