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The existence of small cell thyroid tumors with EWSR1-FLI1 rearrangement together with neuroendocrine and\/or carcinomatous differentiation raises not only differential diagnostic problems but also a very interesting therapeutic dilemma. This review explores the classification of small cell tumors of the thyroid taking into account the immunophenotype and molecular profile of such tumors.<\/jats:p>","DOI":"10.1177\/1066896913510029","type":"journal-article","created":{"date-parts":[[2013,11,25]],"date-time":"2013-11-25T21:54:55Z","timestamp":1385416495000},"page":"197-201","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":14,"title":["Small Cell Tumors of the Thyroid Gland"],"prefix":"10.1177","volume":"22","author":[{"given":"Catarina","family":"Eloy","sequence":"first","affiliation":[{"name":"IPATIMUP (Institute of Molecular Pathology and Immunology of the University of Porto), Porto, Portugal"}]},{"given":"Jos\u00e9 Manuel","family":"Cameselle-Teijeiro","sequence":"additional","affiliation":[{"name":"Clinical University Hospital & University of Santiago de Compostela, Santiago de Compostela, Spain"}]},{"given":"Emmanuel","family":"Rousseau","sequence":"additional","affiliation":[{"name":"Centre Hospitalier de Mouscron, Mouscron, Belgium"}]},{"given":"Manuel","family":"Sobrinho-Sim\u00f5es","sequence":"additional","affiliation":[{"name":"IPATIMUP (Institute of Molecular Pathology and Immunology of the University of Porto), Porto, Portugal"},{"name":"Hospital de S\u00e3o Jo\u00e3o, Porto, Portugal"},{"name":"Medical Faculty of the University of Porto, Porto, Portugal"}]}],"member":"179","published-online":{"date-parts":[[2013,11,25]]},"reference":[{"key":"bibr1-1066896913510029","first-page":"457","volume":"10","author":"Gon\u00e7alves V","year":"1978","journal-title":"J Submicr Cytol"},{"key":"bibr2-1066896913510029","doi-asserted-by":"publisher","DOI":"10.1016\/j.humpath.2006.06.008"},{"key":"bibr3-1066896913510029","doi-asserted-by":"publisher","DOI":"10.1177\/1066896910393506"},{"key":"bibr4-1066896913510029","doi-asserted-by":"publisher","DOI":"10.1177\/1066896913486696"},{"key":"bibr5-1066896913510029","doi-asserted-by":"publisher","DOI":"10.1177\/1066896913486697"},{"key":"bibr6-1066896913510029","doi-asserted-by":"publisher","DOI":"10.1002\/hed.23240"},{"key":"bibr7-1066896913510029","doi-asserted-by":"publisher","DOI":"10.1007\/s00428-011-1138-2"},{"key":"bibr8-1066896913510029","doi-asserted-by":"publisher","DOI":"10.1177\/1066896911405320"},{"key":"bibr9-1066896913510029","doi-asserted-by":"publisher","DOI":"10.1016\/j.prp.2012.03.005"},{"key":"bibr10-1066896913510029","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e3182299cde"},{"key":"bibr11-1066896913510029","doi-asserted-by":"publisher","DOI":"10.1097\/00019606-199802000-00007"},{"key":"bibr12-1066896913510029","doi-asserted-by":"publisher","DOI":"10.1007\/s12032-011-9996-7"},{"key":"bibr13-1066896913510029","doi-asserted-by":"publisher","DOI":"10.1007\/BF01600144"},{"key":"bibr14-1066896913510029","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-199707000-00003"},{"key":"bibr15-1066896913510029","doi-asserted-by":"publisher","DOI":"10.1309\/AJCP7ULS0VSISBEB"},{"key":"bibr16-1066896913510029","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1827.2008.02310.x"}],"container-title":["International Journal of Surgical Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1066896913510029","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1066896913510029","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1066896913510029","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T10:20:01Z","timestamp":1777458001000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1066896913510029"}},"subtitle":["A Review"],"short-title":[],"issued":{"date-parts":[[2013,11,25]]},"references-count":16,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2014,5]]}},"alternative-id":["10.1177\/1066896913510029"],"URL":"https:\/\/doi.org\/10.1177\/1066896913510029","relation":{},"ISSN":["1066-8969","1940-2465"],"issn-type":[{"value":"1066-8969","type":"print"},{"value":"1940-2465","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,11,25]]}}}