{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T23:26:35Z","timestamp":1777850795558,"version":"3.51.4"},"reference-count":29,"publisher":"SAGE Publications","issue":"12","license":[{"start":{"date-parts":[[2014,12,23]],"date-time":"2014-12-23T00:00:00Z","timestamp":1419292800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Feline Medicine and Surgery"],"published-print":{"date-parts":[[2015,12]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>\n                      The aims of the study were to assess the possible effects of sex, age and breed on the evolution of pancreatitis, and to understand if low values of serum ionised calcium ([Ca\n                      <jats:sup>2+<\/jats:sup>\n                      i]) can be considered as a prognostic risk factor for determining the clinical course of the disease.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      A sample of 24 cats (n = 24) with pancreatitis was used and grouped according to the disease progress into two groups: (i) non-fatal (NF) for those that recovered and (ii) fatal (F) for those that died. Quantification of [Ca\n                      <jats:sup>2+<\/jats:sup>\n                      i] and feline pancreatic lipase (fPL) was carried out for each patient at two different times: T1 (day of diagnosis) and T2 (day of recovery or death). For statistical analysis, P values\u2009\u2009&lt;0.05 were considered significant. \u2009\u2009\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      At T1, 58.3% of patients presented with hypocalcaemia, 33.3% with normocalcaemia and 8.3% with hypercalcaemia. The [Ca\n                      <jats:sup>2+<\/jats:sup>\n                      i] mean values were higher in the F group than in NF. At T2, 75.0% of patients showed normocalcaemia and 25.0% hypocalcaemia. The mean value of [Ca\n                      <jats:sup>2+<\/jats:sup>\n                      i] \u2009\u2009for F at T2 was 0.88 \u00b1 0.23 mmol\/l, whereas for NF it was 1.10 \u00b1 0.11 mmol\/l. There was no sex or age predisposition for disease development, but a breed effect was noted (domestic shorthair cats were more prone to developing pancreatitis).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions and relevance<\/jats:title>\n                    <jats:p>\n                      The results suggest that hypocalcaemia is common in patients with pancreatitis and that [Ca\n                      <jats:sup>2+<\/jats:sup>\n                      i] may be used as a prognostic risk factor for predicting the clinical course of the disease, with values \u2a7d1 mmol\/l corresponding to a poor prognosis.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1098612x14564203","type":"journal-article","created":{"date-parts":[[2014,12,23]],"date-time":"2014-12-23T23:57:18Z","timestamp":1419379038000},"page":"984-990","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":18,"title":["Serum ionised calcium as a prognostic risk factor in the clinical course of pancreatitis in cats"],"prefix":"10.1177","volume":"17","author":[{"given":"Cla\u00fadia","family":"Dias","sequence":"first","affiliation":[{"name":"Faculty of Veterinary Medicine, University of Lisbon (FMV\/ULisboa), Portugal"}]},{"given":"L Miguel","family":"Carreira","sequence":"additional","affiliation":[{"name":"Faculty of Veterinary Medicine, University of Lisbon (FMV\/ULisboa), Portugal"},{"name":"Interdisciplinary Centre of Research in Animal Health (CIISA), FMV\/ULisboa, Portugal"},{"name":"Anjos of Assis Veterinary Medicine Center (CMVAA), Barreiro, Portugal"}]}],"member":"179","published-online":{"date-parts":[[2014,12,23]]},"reference":[{"key":"bibr1-1098612X14564203","first-page":"137","volume-title":"Proceedings of the European Veterinary Conference Voorjaarsdagen, the Netherlands","author":"Noort RV.","year":"2010"},{"key":"bibr2-1098612X14564203","unstructured":"Zoran DL. Feline pancreatitis: diagnosis and treatment connections to cholangitis? Proceedings of the American Board of Veterinary Practitioners Symposium; 2012 Apr; San Antonio, TX, USA. http:\/\/www.vin.com\/Members\/Proceedings\/Proceedings.plx?CID=ABVP2012&PID=83"},{"key":"bibr3-1098612X14564203","unstructured":"Marks SL. Feline pancreatitis \u2013 a critical appraisal of diagnosis and management. Western Veterinary Conference, 2009. http:\/\/www.vin.com\/Members\/Proceedings\/Proceedings.plx?CID=WVC2009&PID=50817&O=VIN"},{"key":"bibr4-1098612X14564203","unstructured":"Simpson KW. An update on pancreatitis in dogs and cats. Proceedings of the Western Veterinary Conference; 2012 Feb 19\u201313; Las Vegas, NV, USA. http:\/\/www.vin.com\/Members\/Proceedings\/Proceedings.plx?CID=WVC2012&PID=86"},{"key":"bibr5-1098612X14564203","first-page":"305","volume-title":"Proceedings of the World Small Animal Veterinary Congress;","author":"Mansfield C.","year":"2008"},{"key":"bibr6-1098612X14564203","volume-title":"Edi\u00e7\u00e3o especial","author":"Hernadez J","year":"2010"},{"key":"bibr7-1098612X14564203","unstructured":"Steiner JM. Acute and chronic feline pancreatitis \u2013 diagnostic and therapeutic challenges. Proceedings of the 35th World Small Animal Veterinary Congress; 2010; Geneva, Switzerland. http:\/\/www.vin.com\/Members\/Proceedings\/Proceedings.plx?CID=WSAVA2010&PID"},{"key":"bibr8-1098612X14564203","first-page":"196","volume-title":"Proceedings of the International Congress of the Italian Association of Companion Animal Veterinarians;","author":"Gaschen FP.","year":"2011"},{"key":"bibr9-1098612X14564203","doi-asserted-by":"publisher","DOI":"10.1055\/s-0034-1381810"},{"key":"bibr10-1098612X14564203","unstructured":"Steiner JM. Diagnosis of pancreatitis. Proceedings of the Atlantic Coast Veterinary Conference; 2011 Oct 10\u201313; Atlantic City, NJ, USA.http:\/\/www.vin.com\/Members\/Proceedings\/Proceedings.plx?CID=ACVC2011&PID=68"},{"key":"bibr11-1098612X14564203","doi-asserted-by":"publisher","DOI":"10.17221\/5595-VETMED"},{"key":"bibr12-1098612X14564203","unstructured":"Scherk M. Feline pancreatitis: under-diagnosed and frequently overlooked. International Veterinary Emergency and Critical Care Symposium; 2010 Sep 11\u201315; San Antonio, TX, USA. http:\/\/www.vin.com\/Members\/Proceedings\/Proceedings.plx?CID=IVECCS2010&PID=56943&O=VIN"},{"key":"bibr13-1098612X14564203","first-page":"443","volume-title":"Fluid, electrolyte, and acid\u2013base disorders in small animal practice","author":"Galv\u00e3o JFB","year":"2012","edition":"4"},{"key":"bibr14-1098612X14564203","doi-asserted-by":"publisher","DOI":"10.2460\/javma.2001.219.1105"},{"key":"bibr15-1098612X14564203","doi-asserted-by":"publisher","DOI":"10.1016\/B978-1-4377-0654-3.00013-5"},{"key":"bibr16-1098612X14564203","unstructured":"Willard MD. Pancreatitis: a more common and more difficult diagnosis than we thought. International Veterinary Emergency and Critical Care Symposium; 2010 Sep 11\u201315; San Antonio, TX, USA. http:\/\/www.vin.com\/Members\/Proceedings\/Proceedings.plx?CID=IVECCS2010&PID="},{"key":"bibr17-1098612X14564203","first-page":"143","volume":"37","author":"Gr\u00fcndter VS","year":"1997","journal-title":"Rev Bras Reumatol"},{"key":"bibr18-1098612X14564203","first-page":"468","volume-title":"Proceedings of the North American Veterinary Conference","author":"Matz ME"},{"key":"bibr19-1098612X14564203","first-page":"1704","volume-title":"Textbook of veterinary internal medicine: diseases of the dog and the cat","author":"Washabau RJ.","year":"2010","edition":"7"},{"key":"bibr20-1098612X14564203","doi-asserted-by":"publisher","DOI":"10.1148\/rg.317115046"},{"key":"bibr21-1098612X14564203","first-page":"461","volume-title":"Proceedings of the 36th World Small Animal Veterinary Congress","author":"Little S."},{"key":"bibr22-1098612X14564203","unstructured":"Forman MA. Figure out feline pancreatitis. Proceedings of the American College of Veterinary Medicine; 2012 May 30\u2013Jun 2; New Orleans, LA, USA. http:\/\/www.vin.com\/Members\/Proceedings\/Proceedings.plx?CID=ACVIM2012&PID=84397&O=VIN"},{"key":"bibr23-1098612X14564203","doi-asserted-by":"publisher","DOI":"10.1354\/vp.44-1-39"},{"key":"bibr24-1098612X14564203","unstructured":"Washabau RJ. Canine pancreatic disease: what\u2019s new in diagnosis and therapy? 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