{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T12:53:35Z","timestamp":1791204815378,"version":"4.1.0"},"reference-count":40,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T00:00:00Z","timestamp":1790726400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["R00AG070274"],"award-info":[{"award-number":["R00AG070274"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["R00AG075317"],"award-info":[{"award-number":["R00AG075317"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Alzheimer\u2019s Disease"],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Limited evidence suggests that higher body weight may be associated with improved survival among individuals with dementia relative to those in the normal weight range. The mechanisms underlying this association are uncertain and may include both physiological and methodological factors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To examine the association between weight status at incident dementia and mortality and to assess potential sources of bias.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We examined the association between weight status at incident dementia and mortality in a large, U.S. population-based sample with extended follow-up. We also evaluated potential sources of bias affecting this association, including confounding due to weight loss, collider stratification bias, and survivor bias.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Compared with the normal weight category, class I obesity at incident dementia was associated with a 27% lower risk of mortality (HR 0.73, 95% CI: 0.62\u20130.86). Overweight and class II\/III obesity were also associated with lower mortality. Analyses evaluating potential sources of bias did not support these mechanisms as major contributors to the observed associations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In a large, U.S. population-based sample with extended follow-up, overweight and obesity at incident dementia were associated with lower mortality relative to normal weight. While the underlying mechanisms are not fully understood, these findings suggest that weight status at diagnosis may serve as a useful prognostic indicator alongside other factors.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/13872877261491694","type":"journal-article","created":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T04:14:36Z","timestamp":1790828076000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Body mass index and mortality in incident dementia"],"prefix":"10.1177","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4995-6989","authenticated-orcid":false,"given":"Virginia W.","family":"Chang","sequence":"first","affiliation":[{"name":"School of Global Public Health, New York University"},{"name":"Grossman School of Medicine, New York University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8299-2389","authenticated-orcid":false,"given":"Eleanor","family":"Hayes-Larson","sequence":"additional","affiliation":[{"name":"University of Southern California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3085-4560","authenticated-orcid":false,"given":"Hui","family":"Zheng","sequence":"additional","affiliation":[{"name":"University of Toronto"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1290-9305","authenticated-orcid":false,"given":"Yuan S.","family":"Zhang","sequence":"additional","affiliation":[{"name":"Mailman School of Public Health, Columbia University"},{"name":"Mailman School of Public Health, Columbia University"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,9,30]]},"reference":[{"key":"e_1_3_3_2_2","article-title":"2025 Alzheimer\u2019s disease facts and figures","volume":"21","author":"Alzheimer\u2019s Association","year":"2025","unstructured":"Alzheimer\u2019s Association. 2025 Alzheimer\u2019s disease facts and figures. 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