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We propose a new prognostic approach for type 2 diabetes mellitus based on electronic health records without using the current invasive techniques that are related to the disease (e.g. glucose level or glycated hemoglobin (HbA1c)). Our methodology is based on machine learning frameworks with data enrichment using temporal features. As as result our predictive model achieved an area under the receiver operating characteristics curve with a random forest classifier of 84.22 percent when including data information from 2009 to 2011 to predict diabetic patients in 2012, 83.19 percent when including temporal features, and 83.72 percent after applying temporal features and feature selection. We conclude that he pathology prediction is possible and efficient using the patient\u2019s progression information over the years and without using the invasive techniques that are currently used for type 2 diabetes mellitus classification. <\/jats:p>","DOI":"10.1177\/1460458216663023","type":"journal-article","created":{"date-parts":[[2016,8,27]],"date-time":"2016-08-27T01:30:22Z","timestamp":1472261422000},"page":"194-205","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":16,"title":["Screening diabetes mellitus 2 based on electronic health records using temporal features"],"prefix":"10.1177","volume":"24","author":[{"given":"Angela","family":"Pimentel","sequence":"first","affiliation":[{"name":"Universidade Nova de Lisboa, Portugal"}]},{"given":"Andr\u00e9 V","family":"Carreiro","sequence":"additional","affiliation":[{"name":"INESC-ID, Portugal"}]},{"given":"Rog\u00e9rio T","family":"Ribeiro","sequence":"additional","affiliation":[{"name":"APDP ERC, Portugal"}]},{"given":"Hugo","family":"Gamboa","sequence":"additional","affiliation":[{"name":"Universidade Nova de Lisboa, Portugal"}]}],"member":"179","published-online":{"date-parts":[[2016,8,26]]},"reference":[{"key":"bibr1-1460458216663023","unstructured":"WHO\u2014World Health Organization. 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