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During 6 months, patients with AD and their caregivers were submitted to a biweekly exercise program, including muscle strengthening, aerobics, balance, and postural exercises. The following tests were used: Senior Fitness Test and Incremental Treadmill Test, Disability Assessment for Dementia Scale, Alzheimer Disease Assessment Scale\u2013Cognitive, and Quality of Life\u2013Alzheimer\u2019s. Attendance and retention mean rates were high (86% and 78%, respectively). No adverse events occurred. Results revealed a significant beneficial effect on cardiorespiratory fitness ( P = .028), upper ( P = .018) and lower ( P = .026) body muscle strength, agility ( P = .018), and ability to perform daily activities ( P = .018). Data suggest that a biweekly MT intervention is feasible to conduct in patients with AD. Findings also suggest a potential positive effect on mitigating cognitive decline and in positively influencing quality of life. <\/jats:p>","DOI":"10.1177\/1533317518813555","type":"journal-article","created":{"date-parts":[[2018,12,10]],"date-time":"2018-12-10T05:16:16Z","timestamp":1544418976000},"page":"95-103","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":18,"title":["Feasibility and Impact of a Multicomponent Exercise Intervention in Patients With Alzheimer\u2019s Disease: A Pilot Study"],"prefix":"10.1177","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8839-5726","authenticated-orcid":false,"given":"Fl\u00e1via","family":"Borges-Machado","sequence":"first","affiliation":[{"name":"CIAFEL\u2014Research Centre in Physical Activity, Health and Leisure, Porto, Portugal"},{"name":"Faculty of Sport, University of Porto, Porto, Portugal"}]},{"given":"\u00d3scar","family":"Ribeiro","sequence":"additional","affiliation":[{"name":"CINTESIS\u2014Center for Health Technology and Services Research, Porto, Portugal"},{"name":"Department of Education and Psychology, University of Aveiro, Aveiro, Portugal"}]},{"given":"Arnaldina","family":"Sampaio","sequence":"additional","affiliation":[{"name":"CIAFEL\u2014Research Centre in Physical Activity, Health and Leisure, Porto, Portugal"},{"name":"Faculty of Sport, University of Porto, Porto, Portugal"}]},{"given":"In\u00eas","family":"Marques-Aleixo","sequence":"additional","affiliation":[{"name":"CIAFEL\u2014Research Centre in Physical Activity, Health and Leisure, Porto, Portugal"},{"name":"Lus\u00f3fona University of Porto, Porto, Portugal"}]},{"given":"Joana","family":"Meireles","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, University of Porto, Porto, Portugal"}]},{"given":"Joana","family":"Carvalho","sequence":"additional","affiliation":[{"name":"CIAFEL\u2014Research Centre in Physical Activity, Health and Leisure, Porto, Portugal"},{"name":"Faculty of Sport, University of Porto, Porto, Portugal"}]}],"member":"179","published-online":{"date-parts":[[2018,12,9]]},"reference":[{"key":"bibr1-1533317518813555","volume-title":"The Global Impact of Dementia: An Analysis of Prevalence, Incidence, Cost and Trends","author":"World Alzheimer Report 2015","year":"2015","edition":"1"},{"key":"bibr2-1533317518813555","volume-title":"Dementia: A Public Health Priority","author":"World Health Organization and Alzheimer\u2019s Disease International","year":"2012","edition":"1"},{"key":"bibr3-1533317518813555","volume-title":"Draft Global Action Plan on the Public Health Response to Dementia","author":"Word Health Organization","year":"2017"},{"key":"bibr4-1533317518813555","unstructured":"World Health Organization. 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