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We used a longitudinal convergent mixed methods design and a cross-disciplinary approach that employed techniques from social and computer sciences to ensure a comprehensive evaluation. While cross-disciplinary mixed methods research is also growing, a discussion of its methodological practices, challenges, and strategies is still scarce. This article contributes to mixed methods research by providing lessons learned on how cross-disciplinary mixed studies can be designed and integrated from collection to interpretation, particularly when combining convergent and longitudinal approaches. We also show the value of \u201cdesign-in-action\u201d\u2014that is, the refinement and adjustment of techniques throughout research, as methods \u201ctalk to each other.\u201d <\/jats:p>","DOI":"10.1177\/1558689820977646","type":"journal-article","created":{"date-parts":[[2020,12,21]],"date-time":"2020-12-21T10:38:16Z","timestamp":1608547096000},"page":"88-113","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":11,"title":["Mixing Methods and Sciences: A Longitudinal Cross-Disciplinary Mixed Methods Study on Technology to Address Social Isolation and Loneliness in Later Life"],"prefix":"10.1177","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4490-4322","authenticated-orcid":false,"given":"Barbara","family":"Barbosa Neves","sequence":"first","affiliation":[{"name":"Monash University, Melbourne, Victoria, Australia"}]},{"given":"Ron","family":"Baecker","sequence":"additional","affiliation":[{"name":"University of Toronto, Toronto, Ontario, Canada"}]}],"member":"179","published-online":{"date-parts":[[2020,12,21]]},"reference":[{"key":"bibr1-1558689820977646","doi-asserted-by":"publisher","DOI":"10.2196\/11656"},{"key":"bibr2-1558689820977646","doi-asserted-by":"publisher","DOI":"10.1145\/2661334.2661375"},{"key":"bibr3-1558689820977646","doi-asserted-by":"publisher","DOI":"10.3402\/qhw.v9.26152"},{"key":"bibr4-1558689820977646","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-417235-7.00009-3"},{"key":"bibr5-1558689820977646","doi-asserted-by":"publisher","DOI":"10.2196\/jmir.2306"},{"volume-title":"Research design: Qualitative, quantitative, and mixed methods approaches","year":"2014","author":"Creswell J. 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