{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T23:35:11Z","timestamp":1778283311457,"version":"3.51.4"},"reference-count":60,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2022,2,28]],"date-time":"2022-02-28T00:00:00Z","timestamp":1646006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Infection Prevention"],"published-print":{"date-parts":[[2022,7]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Antimicrobial resistance is exponentially worsening, and the spread of prevalent carbapenem resistant Enterobacteriaceae (CRE) is a major contributor to this global concern. Infection prevention and control strategies are increasingly consolidated key tools to control this worldwide problem.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>To identify, collect and analyse available evidence regarding the impact of infection prevention and control strategies on prevalent CRE dissemination.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Pubmed\u00ae, Scopus\u00ae and Web of Science\u00ae were searched systematically for articles published between 1th January 2017 and 30th June 2020, guided by the research question \u2018What are the most effective and efficient strategies to prevent and control infection\/colonisation caused by Carbapenem resistant Escherichia coli and Carbapenem resistant Klebsiella pneumoniae?\u2019.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Findings<\/jats:title>\n                    <jats:p>Eleven thousand six hundred and thirty-five publications were found, but after applying the inclusion and exclusion criteria, only 30 were selected. The majority of reviewed studies ( n = 24) were performed in outbreak situations, 26 studies occurred in acute care units and of those, 17 in intensive care units . From the set of implemented infection prevention and control measures, in 29 studies surveillance cultures were applied, in 23 studies patients were isolated or cohorted and, in general, all described the implementation of standard and contact precaution measures.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This systematic review underlines the importance of infection prevention and control strategies in CRE dissemination, standing out the need of further studies outside outbreak and intensive care units contexts. Investment increments and training and educating of all involved are also important contributors to shift this problem, but still with relevant gaps in their implementation, in all types of care units, that need to be addressed.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/17571774211066762","type":"journal-article","created":{"date-parts":[[2022,2,28]],"date-time":"2022-02-28T21:47:27Z","timestamp":1646084847000},"page":"167-185","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":15,"title":["Infection prevention and control strategies against carbapenem resistant Enterobacteriaceae \u2013 a systematic review"],"prefix":"10.1177","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3460-2275","authenticated-orcid":false,"given":"Catarina","family":"Santos-Marques","sequence":"first","affiliation":[{"name":"Center for Innovative Care and Health Technology \u2013 ciTechCare, Polytechnic of Leiria, Portugal"},{"name":"Microbiology Laboratory, Biological Sciences Department, Faculty of Pharmacy of University of Porto, Portugal"},{"name":"Research Unit on Applied Molecular Biosciences \u2013 UCIBIO, Portugal"}]},{"given":"Helena","family":"Ferreira","sequence":"additional","affiliation":[{"name":"Microbiology Laboratory, Biological Sciences Department, Faculty of Pharmacy of University of Porto, Portugal"},{"name":"Research Unit on Applied Molecular Biosciences \u2013 UCIBIO, Portugal"}]},{"given":"S\u00f3nia","family":"Gon\u00e7alves Pereira","sequence":"additional","affiliation":[{"name":"Center for Innovative Care and Health Technology \u2013 ciTechCare, Polytechnic of Leiria, Portugal"}]}],"member":"179","published-online":{"date-parts":[[2022,2,28]]},"reference":[{"key":"bibr1-17571774211066762","doi-asserted-by":"publisher","DOI":"10.3947\/ic.2019.51.2.177"},{"key":"bibr2-17571774211066762","doi-asserted-by":"publisher","DOI":"10.1016\/j.idh.2017.05.001"},{"key":"bibr3-17571774211066762","doi-asserted-by":"publisher","DOI":"10.1089\/mdr.2016.0175"},{"key":"bibr4-17571774211066762","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0209609"},{"key":"bibr5-17571774211066762","doi-asserted-by":"publisher","DOI":"10.1007\/s15010-017-1103-3"},{"key":"bibr6-17571774211066762","doi-asserted-by":"publisher","DOI":"10.2217\/fmb-2016-0143"},{"key":"bibr7-17571774211066762","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhin.2019.08.012"},{"key":"bibr8-17571774211066762","doi-asserted-by":"publisher","DOI":"10.1016\/j.jiph.2018.11.003"},{"key":"bibr9-17571774211066762","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2019.00281"},{"key":"bibr10-17571774211066762","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-019-4461-x"},{"key":"bibr11-17571774211066762","unstructured":"Clark M, et al. (2018) Infection Prevention and Control and Management of producing Enterobacteriaceaee: Guidelines for health Care providers in New Zealand Acute and Residential Care Facilities. Wellington New Zealand Government: Ministry of Health, 1\u201359. Available at: https:\/\/www.health.govt.nz\/system\/files\/documents\/publications\/infection-prevention-control-management-carbapenemase-producing-enterobacteriaceae-dec18.pdf."},{"key":"bibr12-17571774211066762","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01689-18"},{"key":"bibr13-17571774211066762","doi-asserted-by":"publisher","DOI":"10.4065\/mcp.2011.0358"},{"key":"bibr60-17571774211066762","doi-asserted-by":"publisher","DOI":"10.22038\/IJBMS.2019.35269.8400"},{"key":"bibr14-17571774211066762","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmi.2019.04.013"},{"key":"bibr15-17571774211066762","doi-asserted-by":"publisher","DOI":"10.1016\/j.jiph.2018.04.003"},{"key":"bibr16-17571774211066762","volume-title":"Surveillance of Antimicrobial Resistance in Europe 2018","author":"European Centre for Disease Prevention and Control","year":"2019"},{"key":"bibr17-17571774211066762","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2019.02767"},{"key":"bibr18-17571774211066762","doi-asserted-by":"publisher","DOI":"10.1089\/mdr.2018.0390"},{"key":"bibr19-17571774211066762","doi-asserted-by":"publisher","DOI":"10.18683\/germs.2020.1190"},{"key":"bibr20-17571774211066762","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(17)30489-9"},{"key":"bibr21-17571774211066762","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijantimicag.2019.05.021"},{"key":"bibr22-17571774211066762","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.d5928"},{"key":"bibr23-17571774211066762","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(15)00473-0"},{"key":"bibr24-17571774211066762","doi-asserted-by":"publisher","DOI":"10.2147\/IDR.S218945"},{"key":"bibr25-17571774211066762","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhin.2018.02.003"},{"key":"bibr26-17571774211066762","doi-asserted-by":"publisher","DOI":"10.1186\/s13756-018-0453-7"},{"key":"bibr27-17571774211066762","unstructured":"Macdonald AS (2018) Complex entanglements: design-led research for infection prevention and control training tools. In: Proceedings of norddesign: design in the era of digitalization, pp. 1\u201310. Available at: https:\/\/www.designsociety.org\/publication\/40929\/Complex+entanglements%3A+design-led+research+for+infection+prevention+and+control+training+tools."},{"key":"bibr28-17571774211066762","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhin.2017.02.024"},{"key":"bibr29-17571774211066762","doi-asserted-by":"publisher","DOI":"10.1186\/s13756-017-0259-z"},{"key":"bibr30-17571774211066762","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajic.2018.01.001"},{"key":"bibr31-17571774211066762","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkx264"},{"key":"bibr32-17571774211066762","doi-asserted-by":"publisher","DOI":"10.1017\/ice.2015.254"},{"key":"bibr33-17571774211066762","unstructured":"National Health Medical Council (2010)\n                      Australian guidelines for the prevention and control of infection in healthcare\n                      . Canberra. Available at: http:\/\/www.nhmrc.gov.au\/guidelines\/publications\/cd33."},{"key":"bibr34-17571774211066762","unstructured":"National Heart, Lung, Blood Institute (NHLBI) (2014) Study quality assessment tools - national heart, lung, and blood Institute, National Institutes of Health. Available at: https:\/\/www.nhlbi.nih.gov\/health-topics\/study-quality-assessment-tools (accessed 24 October 2019)."},{"key":"bibr35-17571774211066762","unstructured":"O\u2019Neill J (2014)\n                      \u2018\n                      Antimicrobial resistance: tackling a crisis for the health and wealth of nations\u2019. Review On Antimicrobial Resistance\n                      Tackling a crisis for the health and wealth of nations_1.pdf. London, 1\u201320. Available at: https:\/\/amr-review.org\/sites\/default\/files\/AMR Review Paper - Tackling a crisis for the health and wealth of nations_1.pdf."},{"key":"bibr36-17571774211066762","unstructured":"Ontario Agency for Health Protection and Promotion (2019).\n                      Carbapenemase-Producing enterobacteriaceae: frequently asked questions\n                      . Toronto. Available at: https:\/\/www.publichealthontario.ca\/-\/media\/documents\/faq-cpe.pdf?la=en."},{"key":"bibr37-17571774211066762","doi-asserted-by":"publisher","DOI":"10.1787\/9789264307599-en"},{"key":"bibr38-17571774211066762","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhin.2018.10.022"},{"key":"bibr39-17571774211066762","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijantimicag.2018.04.004"},{"key":"bibr40-17571774211066762","unstructured":"Public Health Agency of Canada (2012)\n                      Routine Practices and Additional Precautions for Preventing the Transmission of Infection in Healthcare Settings\n                      . Ottawwa. Available at: http:\/\/publications.gc.ca\/collections\/collection_2013\/aspc-phac\/HP40-83-2013-eng.pdf (Accessed 21 February 2019)."},{"key":"bibr41-17571774211066762","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2017.04.026"},{"key":"bibr42-17571774211066762","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.g7647"},{"key":"bibr43-17571774211066762","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhin.2018.12.009"},{"key":"bibr44-17571774211066762","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2018.11.003"},{"key":"bibr45-17571774211066762","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkm055"},{"key":"bibr46-17571774211066762","doi-asserted-by":"publisher","DOI":"10.1016\/j.idc.2017.05.010"},{"key":"bibr47-17571774211066762","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciy752"},{"key":"bibr48-17571774211066762","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkw414"},{"key":"bibr49-17571774211066762","doi-asserted-by":"publisher","DOI":"10.21037\/atm.2019.09.91"},{"key":"bibr50-17571774211066762","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2018-026072"},{"key":"bibr51-17571774211066762","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajic.2007.01.001"},{"key":"bibr52-17571774211066762","doi-asserted-by":"publisher","DOI":"10.1097\/rnj.0000000000000013"},{"key":"bibr53-17571774211066762","unstructured":"World Health Organization (2009)\n                      WHO Guidelines on Hand Hygiene in Health Care - First Global Patient Safety Challenge Clean Care is Safer Care\n                      . Geneva. Available at: https:\/\/apps.who.int\/iris\/bitstream\/handle\/10665\/44102\/\u20099789241597906_eng.pdf;jsessionid=5F9706052AE6A9AE5B56A1FD746A19D6?sequence=1. (accessed 3 February 2019)."},{"key":"bibr54-17571774211066762","volume-title":"Guidelines on Core Components of Infection Prevention and Control Programmes at the National and Acute Health Care Facility Level","author":"World Health Organization","year":"2016"},{"key":"bibr55-17571774211066762","unstructured":"World Health Organization (2016b) Health Care Without Avoidable Infections - the Critical Role of Infection Prevention and Control. Geneva: World Health Organization, 1\u201316. Available at: https:\/\/apps.who.int\/iris\/bitstream\/handle\/10665\/246235\/WHO-HIS-SDS-2016.10-eng.pdf;jsessionid=FA6EBED75EF07BC1244C8115DD5FBE3B?sequence=1."},{"key":"bibr56-17571774211066762","unstructured":"World Health Organization (2019)\n                      Implementation Manual to Prevent and Control the Spread of Carbapenem-Resistant Organisms at the National and Health Care Facility Level\n                      . Geneva, 98. Available at: http:\/\/apps.who.int\/iris."},{"key":"bibr57-17571774211066762","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhin.2018.11.019"},{"key":"bibr58-17571774211066762","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhin.2020.03.031"},{"key":"bibr59-17571774211066762","doi-asserted-by":"publisher","DOI":"10.1186\/s13756-019-0528-0"}],"container-title":["Journal of Infection Prevention"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/17571774211066762","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/17571774211066762","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/17571774211066762","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T13:07:28Z","timestamp":1777381648000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/17571774211066762"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,2,28]]},"references-count":60,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2022,7]]}},"alternative-id":["10.1177\/17571774211066762"],"URL":"https:\/\/doi.org\/10.1177\/17571774211066762","relation":{},"ISSN":["1757-1774","1757-1782"],"issn-type":[{"value":"1757-1774","type":"print"},{"value":"1757-1782","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,2,28]]}}}