{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,21]],"date-time":"2026-03-21T00:32:45Z","timestamp":1774053165529,"version":"3.50.1"},"reference-count":20,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,9,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>We assessed best available data on access and delivery of acute stroke unit (SU) care, intravenous thrombolysis (IVT) and endovascular treatment (EVT) in the European region in 2019 and 2020.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and methods:<\/jats:title>\n                    <jats:p>We compared national data per number of inhabitants and per 100 annual incident first-ever ischaemic strokes (AIIS) in 46 countries. Population estimates and ischaemic stroke incidence were based on United Nations data and the Global Burden of Disease Report 2019, respectively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>The estimated mean number of acute SUs in 2019 was 3.68 (95% CI: 2.90\u20134.45) per one million inhabitants (MIH) with 7\/44 countries having less than one SU per one MIH. The estimated mean annual number of IVTs was 21.03 (95% CI: 15.63\u201326.43) per 100,000 and 17.14% (95% CI: 12.98\u201321.30) of the AIIS in 2019, with highest country rates at 79.19 and 52.66%, respectively, and 15 countries delivering less than 10 IVT per 100,000. The estimated mean annual number of EVTs in 2019 was 7.87 (95% CI: 5.96\u20139.77) per 100,000 and 6.91% (95% CI: 5.15\u20138.67) of AIIS, with 11 countries delivering less than 1.5 EVT per 100,000. Rates of SUs, IVT and EVT were stable in 2020. There was an increase in mean rates of SUs, IVT and EVT compared to similar data from 2016.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Although there was an increase in reperfusion treatment rates in many countries between 2016 and 2019, this was halted in 2020. There are persistent major inequalities in acute stroke treatment in the European region. Tailored strategies directed to the most vulnerable regions should be prioritised.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/23969873231186042","type":"journal-article","created":{"date-parts":[[2023,7,11]],"date-time":"2023-07-11T05:57:12Z","timestamp":1689055032000},"page":"618-628","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":31,"title":["Delivery of acute ischaemic stroke treatments in the European region in 2019 and 2020"],"prefix":"10.1093","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6702-7924","authenticated-orcid":false,"given":"Diana","family":"Aguiar de Sousa","sequence":"first","affiliation":[{"name":"Stroke Center, Lisbon Central University Hospital and Faculty of Medicine, University of Lisbon, Lisbon, Portugal 1"}]},{"given":"Arlene","family":"Wilkie","sequence":"additional","affiliation":[{"name":"Stroke Alliance for Europe, Brussels, Belgium 2"}]},{"given":"Bo","family":"Norrving","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences, Section of Neurology, Lund University, Sk\u00e5ne University Hospital, Lund, Sweden 3"}]},{"given":"Chris","family":"Macey","sequence":"additional","affiliation":[{"name":"Irish Heart Foundation, Dublin, Ireland 4"}]},{"given":"Claudio","family":"Bassetti","sequence":"additional","affiliation":[{"name":"Department of Neurology, Inselspital Bern and Medical Faculty, University of Bern, Bern, Switzerland 5"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8532-6218","authenticated-orcid":false,"given":"Cristina","family":"Tiu","sequence":"additional","affiliation":[{"name":"Department of Clinical Neurosciences, University of Medicine and Pharmacy \u2018Carol Davila\u2019 Bucharest, and Department of Neurology, University Hospital Bucharest, Romania 6"}]},{"given":"Greg","family":"Roth","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Medicine, University of Washington, Seattle, WA, USA 7"}]},{"given":"Grethe","family":"Lunde","sequence":"additional","affiliation":[{"name":"Stroke Alliance for Europe, Brussels, Belgium 2"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7472-3194","authenticated-orcid":false,"given":"Hanne","family":"Christensen","sequence":"additional","affiliation":[{"name":"Department of Neurology, Copenhagen University Hospital, Bispebjerg, Copenhagen, Denmark 8"}]},{"given":"Jens","family":"Fiehler","sequence":"additional","affiliation":[{"name":"Department of Diagnostic and Interventional Neuroradiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany 9"}]},{"given":"Francesca Romana","family":"Pezzella","sequence":"additional","affiliation":[{"name":"Stroke Unit, Department of Neuroscience, San Camillo Forlanini Hospital, Rome, Italy 10"}]},{"given":"Martin","family":"Dichgans","sequence":"additional","affiliation":[{"name":"Institute for Stroke and Dementia Research, University Hospital, Ludwig Maximilian University, Munich and German Center for Neurodegenerative Diseases (DZNE), Munich, Germany 11"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4848-9063","authenticated-orcid":false,"given":"Melinda B","family":"Roaldsen","sequence":"additional","affiliation":[{"name":"Center for Research and Education, University Hospital of North Norway and Department of Clinical Medicine, UiT The Arctic University of Norway, Troms\u00f8, Norway 12"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4772-6565","authenticated-orcid":false,"given":"Peter","family":"Kelly","sequence":"additional","affiliation":[{"name":"Stroke and Neurology Department, Mater University Hospital and Stroke Clinical Trials Network Ireland, University College Dublin, Dublin, Ireland 13"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7458-5166","authenticated-orcid":false,"given":"Robert","family":"Mikulik","sequence":"additional","affiliation":[{"name":"International Clinical Research Center and Department of Neurology, St. Anne\u2019s University Hospital in Brno and Faculty of Medicine at Masaryk University, Brno, Czech Republic 14"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0651-1939","authenticated-orcid":false,"given":"Simona","family":"Sacco","sequence":"additional","affiliation":[{"name":"Department of Biotechnological and Applied Clinical Sciences University of L\u2019Aquila, L\u2019Aquila, Italy 15"}]},{"given":"Valeria","family":"Caso","sequence":"additional","affiliation":[{"name":"Stroke Unit, Santa Maria della Misericordia Hospital, University of Perugia, Perugia, Italy 16"}]},{"given":"Urs","family":"Fischer","sequence":"additional","affiliation":[{"name":"Department of Neurology, University Hospital Basel, University of Basel, Basel, Switzerland 17"}]},{"name":"on behalf of the Steering Committee for the Implementation of the Stroke Action Plan in 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