{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T02:45:06Z","timestamp":1791341106067,"version":"4.3.1"},"reference-count":39,"publisher":"American Society of Hematology","issue":"1","content-domain":{"domain":["ashpublications.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2005,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Donation of hematopoietic stem cells, either through bone marrow or peripheral blood collection, is a generally safe procedure for healthy donors. Serious adverse events are uncommon and death is exceedingly rare. Nevertheless, all donors must be carefully evaluated and fully informed prior to donation. This should be done by clinicians having good understanding of the potential physical and psychological complications of donation and the factors that may increase these risks. Additionally, donors and graft products must be evaluated for the potential to transmit infections and other diseases to the recipient and to satisfy an increasing number of national and international regulatory requirements. Donors must be able to provide informed consent without coercion or pressure. Special attention to the clinical, psychological and social needs of pediatric donors is necessary.<\/jats:p>","DOI":"10.1182\/asheducation-2005.1.469","type":"journal-article","created":{"date-parts":[[2005,11,23]],"date-time":"2005-11-23T01:29:34Z","timestamp":1132709374000},"page":"469-475","update-policy":"https:\/\/doi.org\/10.1182\/blood.2019cm0000","source":"Crossref","is-referenced-by-count":61,"title":["Evaluation of Hematopoietic Stem Cell Donors"],"prefix":"10.1182","volume":"2005","author":[{"given":"Mary M.","family":"Horowitz","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dennis L.","family":"Confer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"234","reference":[{"key":"2019111703565972000_R1","doi-asserted-by":"crossref","unstructured":"Bakken R, van Walreaven A-M, Egeland T. Donor commitment and patient needs. 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Allogeneic blood progenitor cell collection in normal donors after mobilization with filgrastim: The M.D. Anderson Cancer Center experience. Transfusion. 1999;39:555\u2013560.","DOI":"10.1046\/j.1537-2995.1999.39060555.x"},{"key":"2019111703565972000_R12","doi-asserted-by":"crossref","unstructured":"Froberg MK, Garg UC, Stroncek DF, Geis M, McCullough J, Brown DM. Changes in serum osteocalcin and bone-specific alkaline phosphatase are associated with bone pain in donors receiving granulocyte-colony-stimulating factor for peripheral blood stem and progenitor cell collection. Transfusion. 1999;39:410\u2013414.","DOI":"10.1046\/j.1537-2995.1999.39499235675.x"},{"key":"2019111703565972000_R13","doi-asserted-by":"crossref","unstructured":"Stroncek D, McCullough J. Policies and procedures for the establishment of an allogeneic blood stem cell collection programme. 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Granulocyte colony-stimulating factor-induced sickle cell crisis and multiorgan dysfunction in a patient with compound heterozygous sickle cell\/B+ thalassemia. Blood. 2001;97:3998\u20133999.","DOI":"10.1182\/blood.V97.12.3998"},{"key":"2019111703565972000_R17","doi-asserted-by":"crossref","unstructured":"Kang E, Areman E, David-Ocampo V, et al. Mobilization, collection, and processing of peripheral blood stem cells in individuals with sickle cell trait. Blood. 2002;99:850\u2013855.","DOI":"10.1182\/blood.V99.3.850"},{"key":"2019111703565972000_R18","unstructured":"Becker PS, Wagle M, Matous S, et al. Spontaneous splenic rupture following administration of granulocyte colony-stimulating factor (G-CSF): Occurrence in an allogeneic donor of peripheral blood stem cells. Biol Blood Marrow Transplant. 1997;3:45\u201349."},{"key":"2019111703565972000_R19","doi-asserted-by":"crossref","unstructured":"Falzetti F, Aversa F, Minelli O, Tabilio A. 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