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DVT and PE treatment in pregnancy is also challenging due to this lack of validated diagnostic approaches, changes in maternal physiology, and the need for intact hemostasis at the time of delivery\/epidural analgesia. Prevention requires an optimal balancing of absolute increased bleeding risk from pharmacologic thromboprophylaxis and the absolute benefit of reduced DVT and PE, which, while serious, are relatively uncommon.<\/jats:p>","DOI":"10.1182\/asheducation-2010.1.173","type":"journal-article","created":{"date-parts":[[2011,1,16]],"date-time":"2011-01-16T19:08:48Z","timestamp":1295204928000},"page":"173-180","update-policy":"https:\/\/doi.org\/10.1182\/blood.2019cm0000","source":"Crossref","is-referenced-by-count":26,"title":["Evidence Base for the Management of Venous Thromboembolism in Pregnancy"],"prefix":"10.1182","volume":"2010","author":[{"given":"Marc","family":"Rodger","sequence":"first","affiliation":[{"name":"Ottawa Hospital, Ottawa Hospital Research Institute, and University of Ottawa, Ottawa, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"234","reference":[{"key":"2019111716294485400_B1","first-page":"1055","article-title":"Maternal mortality in the United States, 1979\u20131986","volume":"76","author":"Atrash","year":"1990","journal-title":"Obstet Gynecol"},{"key":"2019111716294485400_B2","volume-title":"Why mothers die. 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