{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,8,29]],"date-time":"2024-08-29T15:05:56Z","timestamp":1724943956412},"reference-count":17,"publisher":"American Society of Hematology","issue":"1","content-domain":{"domain":["ashpublications.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2010,12,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>An 18-year-old African-American male with sickle cell disease (SCD) is admitted to the hospital with a vaso-occlusive pain crisis affecting his chest and right upper extremity. He has a history of asthma but does not have a fever or respiratory symptoms, and a chest X-ray is negative for an infiltrate. He is treated with intravenous fluids and morphine. You are asked about the potential efficacy of systemic corticosteroids as an adjunctive treatment for pain control.<\/jats:p>","DOI":"10.1182\/asheducation-2010.1.416","type":"journal-article","created":{"date-parts":[[2011,1,16]],"date-time":"2011-01-16T19:08:48Z","timestamp":1295204928000},"page":"416-417","update-policy":"http:\/\/dx.doi.org\/10.1182\/blood.2019cm0000","source":"Crossref","is-referenced-by-count":8,"title":["Evidence-Based Mini-Review: Are Systemic Corticosteroids an Effective Treatment for Acute Pain in Sickle Cell Disease?"],"prefix":"10.1182","volume":"2010","author":[{"given":"L. 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ClinicalTrials.gov website\n          Steroid treatment for sickle cell pain crises\n          Accessed October 10, 2010\n          Available from: http:\/\/clinicaltrials.gov\/ct2\/show\/NCT00263562?term=sickle+cell+and+steroids&rank=1"},{"issue":"11","key":"2019111717112753900_B13","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1056\/NEJM199403173301101","article-title":"High-dose intravenous methylprednisolone therapy for pain in children and adolescents with sickle cell disease","volume":"330","author":"Griffin","year":"1994","journal-title":"N Engl J Med"},{"issue":"9","key":"2019111717112753900_B14","doi-asserted-by":"crossref","first-page":"3082","DOI":"10.1182\/blood.V92.9.3082","article-title":"Beneficial effect of intravenous dexamethasone in children with mild to moderately severe acute chest syndrome complicating sickle cell 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