{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T06:12:55Z","timestamp":1774937575436,"version":"3.50.1"},"reference-count":14,"publisher":"American Society of Hematology","issue":"4","content-domain":{"domain":["ashpublications.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2002,8,15]]},"abstract":"<jats:p>We describe a woman with severe neutropenia and dependency on red blood cell transfusions who had previously undergone Billroth II surgery and whose bone marrow (BM) showed morphologic characteristics typical of myelodysplastic syndrome (MDS) with ringed sideroblasts. She had transient reversal of anemia and severe neutropenia after therapy with erythropoietin and granulocyte colony-stimulating factor. Because of relapse while receiving growth factors, the patient was referred for allogeneic BM transplantation. A pretransplantation nutritional evaluation revealed severe copper deficiency, and her hematologic abnormalities resolved fully with copper therapy. This case shows that copper deficiency should be an integral part of the differential diagnosis of sideroblastic MDS, even in patients not requiring parenteral nutrition.<\/jats:p>","DOI":"10.1182\/blood-2002-01-0256","type":"journal-article","created":{"date-parts":[[2002,10,1]],"date-time":"2002-10-01T17:48:18Z","timestamp":1033494498000},"page":"1493-1495","update-policy":"https:\/\/doi.org\/10.1182\/blood.2019cm0000","source":"Crossref","is-referenced-by-count":187,"title":["Copper deficiency masquerading as myelodysplastic syndrome"],"prefix":"10.1182","volume":"100","author":[{"given":"Xylina T.","family":"Gregg","sequence":"first","affiliation":[{"name":"From Baylor College of Medicine, Houston, TX; and the Department of Pathology, University of Alabama at Birmingham."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vishnu","family":"Reddy","sequence":"additional","affiliation":[{"name":"From Baylor College of Medicine, Houston, TX; and the Department of Pathology, University of Alabama at Birmingham."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Josef T.","family":"Prchal","sequence":"additional","affiliation":[{"name":"From Baylor College of Medicine, Houston, TX; and the Department of Pathology, University of Alabama at Birmingham."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"234","reference":[{"key":"2020021221524640800_B1","doi-asserted-by":"crossref","first-page":"470","DOI":"10.7326\/0003-4819-80-4-470","article-title":"Anemia and neutropenia caused by copper deficiency.","volume":"80","author":"Dunlap","year":"1974","journal-title":"Ann Intern Med."},{"key":"2020021221524640800_B2","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1177\/0148607194018002190","article-title":"Copper deficiency with pancytopenia during total parenteral nutrition.","volume":"18","author":"Wasa","year":"1994","journal-title":"JPEN J Parenter Enteral 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