{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,10]],"date-time":"2026-11-10T10:25:43Z","timestamp":1794306343377,"version":"4.9.0"},"reference-count":146,"publisher":"American Society of Hematology","issue":"7","content-domain":{"domain":["ashpublications.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2003,4,1]]},"abstract":"<jats:p>The POEMS syndrome (coined to refer to polyneuropathy, organomegaly, endocrinopathy, M protein, and skin changes) remains poorly understood. Ambiguity exists over the features necessary to establish the diagnosis, treatment efficacy, and prognosis. We identified 99 patients with POEMS syndrome. Minimal criteria were a sensorimotor peripheral neuropathy and evidence of a monoclonal plasmaproliferative disorder. To distinguish POEMS from neuropathy associated with monoclonal gammopathy of undetermined significance, additional criteria were included: a bone lesion, Castleman disease, organomegaly (or lymphadenopathy), endocrinopathy, edema (peripheral edema, ascites, or effusions), and skin changes. The median age at presentation was 51 years; 63% were men. Median survival was 165 months. With the exception of fingernail clubbing (P\u2009=\u2009.03) and extravascular volume overload (P\u2009=\u2009.04), no presenting feature, including the number of presenting features, was predictive of survival. Response to therapy (P\u2009&lt;\u2009.001) was predictive of survival. Pulmonary hypertension, renal failure, thrombotic events, and congestive heart failure were observed and appear to be part of the syndrome. In 18 patients (18%), new disease manifestations developed over time. More than 50% of patients had a response to radiation, and 22% to 50% had responses to prednisone and a combination of melphalan and prednisone, respectively. We conclude that the median survival of patients with POEMS syndrome is 165 months, independent of the number of syndrome features, bone lesions, or plasma cells at diagnosis. Additional features of the syndrome often develop, but the complications of classic multiple myeloma rarely develop.<\/jats:p>","DOI":"10.1182\/blood-2002-07-2299","type":"journal-article","created":{"date-parts":[[2003,3,17]],"date-time":"2003-03-17T15:22:55Z","timestamp":1047914575000},"page":"2496-2506","update-policy":"https:\/\/doi.org\/10.1182\/blood.2019cm0000","source":"Crossref","is-referenced-by-count":681,"title":["POEMS syndrome: definitions and long-term outcome"],"prefix":"10.1182","volume":"101","author":[{"given":"Angela","family":"Dispenzieri","sequence":"first","affiliation":[{"name":"From the Division of Hematology and Internal Medicine; Section of Biostatistics; Division of Endocrinology, Diabetes, Metabolism, Nutrition, and Internal Medicine; and Department of Neurology; Mayo Clinic, Rochester, MN."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert A.","family":"Kyle","sequence":"additional","affiliation":[{"name":"From the Division of Hematology and Internal Medicine; Section of Biostatistics; Division of Endocrinology, Diabetes, Metabolism, Nutrition, and Internal Medicine; and Department of Neurology; Mayo Clinic, Rochester, MN."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martha Q.","family":"Lacy","sequence":"additional","affiliation":[{"name":"From the Division of Hematology and Internal Medicine; Section of Biostatistics; Division of Endocrinology, Diabetes, Metabolism, Nutrition, and Internal Medicine; and Department of Neurology; Mayo Clinic, Rochester, MN."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S. Vincent","family":"Rajkumar","sequence":"additional","affiliation":[{"name":"From the Division of Hematology and Internal Medicine; Section of Biostatistics; Division of Endocrinology, Diabetes, Metabolism, Nutrition, and Internal Medicine; and Department of Neurology; Mayo Clinic, Rochester, MN."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Terry M.","family":"Therneau","sequence":"additional","affiliation":[{"name":"From the Division of Hematology and Internal Medicine; Section of Biostatistics; Division of Endocrinology, Diabetes, Metabolism, Nutrition, and Internal Medicine; and Department of Neurology; Mayo Clinic, Rochester, MN."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dirk R.","family":"Larson","sequence":"additional","affiliation":[{"name":"From the Division of Hematology and Internal Medicine; Section of Biostatistics; Division of Endocrinology, Diabetes, Metabolism, Nutrition, and Internal Medicine; and Department of Neurology; Mayo Clinic, Rochester, MN."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip R.","family":"Greipp","sequence":"additional","affiliation":[{"name":"From the Division of Hematology and Internal Medicine; Section of Biostatistics; Division of Endocrinology, Diabetes, Metabolism, Nutrition, and Internal Medicine; and Department of Neurology; Mayo Clinic, Rochester, MN."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas E.","family":"Witzig","sequence":"additional","affiliation":[{"name":"From the Division of Hematology and Internal Medicine; Section of Biostatistics; Division of Endocrinology, Diabetes, Metabolism, Nutrition, and Internal Medicine; and Department of Neurology; Mayo Clinic, Rochester, MN."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rita","family":"Basu","sequence":"additional","affiliation":[{"name":"From the Division of Hematology and Internal Medicine; Section of Biostatistics; Division of Endocrinology, Diabetes, Metabolism, Nutrition, and Internal Medicine; and Department of Neurology; Mayo Clinic, Rochester, MN."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guillermo A.","family":"Suarez","sequence":"additional","affiliation":[{"name":"From the Division of Hematology and Internal Medicine; Section of Biostatistics; Division of Endocrinology, Diabetes, Metabolism, Nutrition, and Internal Medicine; and Department of Neurology; Mayo Clinic, Rochester, MN."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rafael","family":"Fonseca","sequence":"additional","affiliation":[{"name":"From the Division of Hematology and Internal Medicine; Section of Biostatistics; Division of Endocrinology, Diabetes, Metabolism, Nutrition, and Internal Medicine; and Department of Neurology; Mayo Clinic, Rochester, MN."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John A.","family":"Lust","sequence":"additional","affiliation":[{"name":"From the Division of Hematology and Internal Medicine; Section of Biostatistics; Division of Endocrinology, Diabetes, Metabolism, Nutrition, and Internal Medicine; and Department of Neurology; Mayo Clinic, Rochester, MN."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Morie A.","family":"Gertz","sequence":"additional","affiliation":[{"name":"From the Division of Hematology and Internal Medicine; Section of Biostatistics; Division of Endocrinology, Diabetes, Metabolism, Nutrition, and Internal Medicine; and Department of Neurology; Mayo Clinic, Rochester, MN."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"234","reference":[{"key":"2019111822324216400_B1","doi-asserted-by":"crossref","first-page":"802","DOI":"10.1136\/bmj.2.4996.802","article-title":"Peripheral neuritis in myelomatosis.","volume":"2","author":"Crow","year":"1956","journal-title":"Brit Med J."},{"key":"2019111822324216400_B2","doi-asserted-by":"crossref","first-page":"892","DOI":"10.1001\/archinte.1979.03630450038013","article-title":"Plasma cell neoplasia with osteosclerotic lesions: a study of five cases and a review of the literature.","volume":"139","author":"Driedger","year":"1979","journal-title":"Arch Intern Med."},{"key":"2019111822324216400_B3","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1212\/WNL.27.7.675","article-title":"Polyneuropathy, skin hyperpigmentation, edema, and hypertrichosis in localized osteosclerotic myeloma.","volume":"27","author":"Iwashita","year":"1977","journal-title":"Neurology."},{"key":"2019111822324216400_B4","doi-asserted-by":"crossref","first-page":"1040","DOI":"10.1002\/1097-0142(1971)28:4<1040::AID-CNCR2820280430>3.0.CO;2-A","article-title":"Osteosclerotic myeloma and peripheral neuropathy: a case report.","volume":"28","author":"Mangalik","year":"1971","journal-title":"Cancer."},{"key":"2019111822324216400_B5","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1212\/WNL.33.2.202","article-title":"Osteosclerotic myeloma and peripheral neuropathy.","volume":"33","author":"Kelly","year":"1983","journal-title":"Neurology."},{"key":"2019111822324216400_B6","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1259\/0007-1285-56-662-145-a","article-title":"Sclerotic bone deposits in multiple myeloma [letter].","volume":"56","author":"Evison","year":"1983","journal-title":"Br J Radiol."},{"key":"2019111822324216400_B7","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1111\/j.0954-6820.1980.tb01167.x","article-title":"Osteosclerotic myeloma with polyneuropathy.","volume":"208","author":"Reitan","year":"1980","journal-title":"Acta Med Scand."},{"key":"2019111822324216400_B8","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1212\/WNL.34.6.712","article-title":"The Crow-Fukase syndrome: a study of 102 cases in Japan.","volume":"34","author":"Nakanishi","year":"1984","journal-title":"Neurology."},{"key":"2019111822324216400_B9","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1097\/00005792-198007000-00005","article-title":"Plasma cell neoplasia with peripheral polyneuropathy: a study of five cases and a review of the literature.","volume":"59","author":"Driedger","year":"1980","journal-title":"Medicine."},{"key":"2019111822324216400_B10","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1007\/BF01762445","article-title":"Myelom und Nervensystem: U\u0308ber eine bisher nicht beschriebene mit eigentu\u0308mlichen Hautvera\u0308nderungen einhergehende Polyneuritis bei einem plasmazellula\u0308ren Myelom des Sternums.","volume":"147","author":"Scheinker","year":"1938","journal-title":"Deutsche Zeitschrift fu\u0308r Nervenheilkunde."},{"key":"2019111822324216400_B11","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1136\/jnnp.30.5.432","article-title":"The relation between chronic polyneuropathy and osteosclerotic myeloma.","volume":"30","author":"Morley","year":"1967","journal-title":"J Neurol Neurosurg Psychiatry."},{"key":"2019111822324216400_B12","first-page":"2444","article-title":"Solitary myeloma causing polyneuritis and endocrine disorders [in Japanese].","volume":"26","author":"Shimpo","year":"1968","journal-title":"Nippon Rinsho."},{"key":"2019111822324216400_B13","first-page":"240","article-title":"Polyneuropathy in the osteosclerotic form of multiple myeloma.","volume":"93","author":"Mayo","year":"1968","journal-title":"Trans Am Neurol Assoc."},{"key":"2019111822324216400_B14","first-page":"657","article-title":"Report of a case of solitary plasmacytoma in the abdomen presenting with polyneuropathy and endocrinological disorders [abstract].","volume":"9","author":"Fukase","year":"1969","journal-title":"Clin Neurol."},{"key":"2019111822324216400_B15","doi-asserted-by":"crossref","first-page":"490","DOI":"10.7326\/0003-4819-81-4-490","article-title":"Syndrome of plasma cell dyscrasia, polyneuropathy, and endocrine disturbances: report of a case.","volume":"81","author":"Imawari","year":"1974","journal-title":"Ann Intern Med."},{"key":"2019111822324216400_B16","first-page":"1246","article-title":"Osteosclerotic myeloma with peripheral neuropathy.","volume":"48","author":"Getaz","year":"1974","journal-title":"S Afr Med J."},{"key":"2019111822324216400_B17","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1111\/j.0954-6820.1978.tb14877.x","article-title":"Osteosclerotic \u201cplasmocytoma\u201d with polyneuropathy, hypertrichosis and diabetes.","volume":"203","author":"Waldenstro\u0308m","year":"1978","journal-title":"Acta Med Scand."},{"key":"2019111822324216400_B18","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1136\/pgmj.56.656.427","article-title":"Plasma cell dyscrasia with polyneuritis and dermato-endocrine alterations: report of a new case outside Japan.","volume":"56","author":"Moya-Mir","year":"1980","journal-title":"Postgrad Med J."},{"key":"2019111822324216400_B19","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1097\/00005792-198007000-00006","article-title":"Plasma cell dyscrasia with polyneuropathy, organomegaly, endocrinopathy, M protein, and skin changes: the POEMS syndrome: report on two cases and a review of the literature.","volume":"59","author":"Bardwick","year":"1980","journal-title":"Medicine."},{"key":"2019111822324216400_B20","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1017\/S0317167100048794","article-title":"Polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy and skin changes (POEMS) syndrome.","volume":"21","author":"Milanov","year":"1994","journal-title":"Can J Neurol Sci."},{"key":"2019111822324216400_B21","first-page":"86","article-title":"Skin changes in POEMS syndrome.","volume":"84","author":"Longo","year":"1999","journal-title":"Haematologica."},{"key":"2019111822324216400_B22","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1016\/0002-9343(94)90350-6","article-title":"POEMS syndrome: a study of 25 cases and a review of the literature. French Study Group on POEMS syndrome.","volume":"97","author":"Soubrier","year":"1994","journal-title":"Am J Med."},{"key":"2019111822324216400_B23","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1016\/S0140-6736(96)91261-1","article-title":"Greatly raised vascular endothelial growth factor (VEGF) in POEMS syndrome [letter].","volume":"347","author":"Watanabe","year":"1996","journal-title":"Lancet."},{"key":"2019111822324216400_B24","doi-asserted-by":"crossref","first-page":"1390","DOI":"10.1002\/(SICI)1097-4598(199811)21:11<1390::AID-MUS5>3.0.CO;2-4","article-title":"Overproduction of vascular endothelial growth factor\/vascular permeability factor is causative in Crow-Fukase (POEMS) syndrome.","volume":"21","author":"Watanabe","year":"1998","journal-title":"Muscle Nerve."},{"key":"2019111822324216400_B25","doi-asserted-by":"crossref","first-page":"786","DOI":"10.1002\/art.1780400430","article-title":"Growth factors in POEMS syndrome: evidence for a marked increase in circulating vascular endothelial growth factor.","volume":"40","author":"Soubrier","year":"1997","journal-title":"Arthritis Rheum."},{"key":"2019111822324216400_B26","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1097\/00005792-199607000-00005","article-title":"Acute arterial obliteration: a new feature of the POEMS syndrome?","volume":"75","author":"Lesprit","year":"1996","journal-title":"Medicine."},{"key":"2019111822324216400_B27","first-page":"813","article-title":"Arterial obliteration in POEMS syndrome: possible role of vascular endothelial growth factor.","volume":"25","author":"Soubrier","year":"1998","journal-title":"J Rheumatol."},{"key":"2019111822324216400_B28","first-page":"293","article-title":"Soluble immune mediators in POEMS syndrome with pulmonary hypertension: case report and review of the literature.","volume":"10","author":"Feinberg","year":"1999","journal-title":"Crit Rev Oncog."},{"key":"2019111822324216400_B29","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1016\/S0272-6386(99)70386-0","article-title":"Growth factors and proinflammatory cytokines in the renal involvement of POEMS syndrome.","volume":"34","author":"Soubrier","year":"1999","journal-title":"Am J Kidney Dis."},{"key":"2019111822324216400_B30","doi-asserted-by":"crossref","first-page":"1051","DOI":"10.1002\/1097-4598(200007)23:7<1051::AID-MUS7>3.0.CO;2-V","article-title":"Highly concentrated vascular endothelial growth factor in platelets in Crow-Fukase syndrome.","volume":"23","author":"Hashiguchi","year":"2000","journal-title":"Muscle Nerve."},{"key":"2019111822324216400_B31","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1080\/01621459.1958.10501452","article-title":"Nonparametric estimation from incomplete observations.","volume":"53","author":"Kaplan","year":"1958","journal-title":"J Am Stat Assoc."},{"key":"2019111822324216400_B32","doi-asserted-by":"crossref","first-page":"185","DOI":"10.2307\/2344317","article-title":"Asymptotically efficient rank in variant test procedures.","volume":"135","author":"Peto","year":"1972","journal-title":"J R Stat Soc A."},{"key":"2019111822324216400_B33","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1111\/j.2517-6161.1972.tb00899.x","article-title":"Regression models and life tables.","volume":"34","author":"Cox","year":"1972","journal-title":"J R Stat Soc B."},{"key":"2019111822324216400_B34","first-page":"543","article-title":"Plasma cell dyscrasia with polyneuropathy and endocrine disorder: clinical and laboratory features of 109 reported cases.","volume":"13","author":"Takatsuki","year":"1983","journal-title":"Jpn J Clin Oncol."},{"key":"2019111822324216400_B35","doi-asserted-by":"crossref","first-page":"50","DOI":"10.2169\/internalmedicine.31.50","article-title":"An autopsy case of Crow-Fukase syndrome which developed 18 years after the first manifestation of plasmacytoma.","volume":"31","author":"Sakemi","year":"1992","journal-title":"Intern Med."},{"key":"2019111822324216400_B36","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1016\/0002-9343(88)90277-X","article-title":"POEMS syndrome presenting as systemic sclerosis: clinical and pathologic study of a case with microangiopathic glomerular lesions.","volume":"84","author":"Viard","year":"1988","journal-title":"Am J Med."},{"key":"2019111822324216400_B37","doi-asserted-by":"crossref","first-page":"1318","DOI":"10.1038\/sj.leu.2400733","article-title":"POEMS syndrome: report on six patients with unusual clinical signs, elevated levels of cytokines, macrophage involvement and chromosomal aberrations of bone marrow plasma cells.","volume":"11","author":"Rose","year":"1997","journal-title":"Leukemia."},{"key":"2019111822324216400_B38","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/0039-6257(90)90091-9","article-title":"When do optic disc edema and peripheral neuropathy constitute poetry?","volume":"35","author":"Brazis","year":"1990","journal-title":"Surv Ophthalmol."},{"key":"2019111822324216400_B39","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1159\/000206876","article-title":"Melphalan-induced pulmonary fibrosis in osteosclerotic myeloma.","volume":"69","author":"Mufti","year":"1983","journal-title":"Acta Haematol."},{"key":"2019111822324216400_B40","doi-asserted-by":"crossref","first-page":"1760","DOI":"10.1183\/09031936.96.09081760","article-title":"Pulmonary hypertension associated with POEMS syndrome.","volume":"9","author":"Ribadeau-Dumas","year":"1996","journal-title":"Eur Respir J."},{"key":"2019111822324216400_B41","doi-asserted-by":"crossref","first-page":"674","DOI":"10.2169\/internalmedicine.34.674","article-title":"Thiamine deficiency and pulmonary hypertension in Crow-Fukase syndrome.","volume":"34","author":"Okura","year":"1995","journal-title":"Intern Med."},{"key":"2019111822324216400_B42","doi-asserted-by":"crossref","first-page":"556","DOI":"10.2169\/internalmedicine.32.556","article-title":"Crow-Fukase syndrome associated with pulmonary hypertension.","volume":"32","author":"Iwasaki","year":"1993","journal-title":"Intern Med."},{"key":"2019111822324216400_B43","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1164\/ajrccm.157.3.9707095","article-title":"Pulmonary hypertension in POEMS syndrome: a new feature mediated by cytokines.","volume":"157","author":"Lesprit","year":"1998","journal-title":"Am J Respir Crit Care Med."},{"key":"2019111822324216400_B44","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1034\/j.1600-0560.2000.027002087.x","article-title":"Glomeruloid hemangioma in POEMS syndrome shows two different immunophenotypic endothelial cells.","volume":"27","author":"Kishimoto","year":"2000","journal-title":"J Cutan Pathol."},{"key":"2019111822324216400_B45","first-page":"1007","article-title":"Reversible pulmonary hypertension in POEMS syndrome: another etiology of triggered pulmonary vasculopathy?","volume":"16","author":"Paciocco","year":"2000","journal-title":"Can J Cardiol."},{"key":"2019111822324216400_B46","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1536\/ihj.38.877","article-title":"Cardiomyopathy in a case of Crow-Fukase syndrome.","volume":"38","author":"Shimizu","year":"1997","journal-title":"Jpn Heart J."},{"key":"2019111822324216400_B47","first-page":"1059","article-title":"Recurrent cerebrovascular insult\u2014manifestation of POEMS syndrome? [in German].","volume":"128","author":"Forster","year":"1998","journal-title":"Schweiz Med Wochenschr."},{"key":"2019111822324216400_B48","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1177\/003693308903400504","article-title":"The endocrinopathy of POEMS syndrome.","volume":"34","author":"Stewart","year":"1989","journal-title":"Scott Med J."},{"key":"2019111822324216400_B49","first-page":"456","article-title":"Crow-Fukase syndrome associated with Castleman disease showing hypertrophic cranial pachymeningitis and bilateral internal carotid artery occlusion [in Japanese].","volume":"39","author":"Hori","year":"1999","journal-title":"Rinsho Shinkeigaku."},{"key":"2019111822324216400_B50","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/0049-0172(92)90015-6","article-title":"POEMS syndrome with myocardial infarction: observations concerning pathogenesis and review of the literature.","volume":"22","author":"Manning","year":"1992","journal-title":"Semin Arthritis Rheum."},{"key":"2019111822324216400_B51","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1177\/014107688207500714","article-title":"Plasma cell dyscrasia with polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy and skin changes: the POEMS syndrome.","volume":"75","author":"Solomons","year":"1982","journal-title":"J R Soc Med."},{"key":"2019111822324216400_B52","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1002\/art.1780290218","article-title":"Light and electron microscopic findings in POEMS, or Japanese multisystem syndrome.","volume":"29","author":"Semble","year":"1986","journal-title":"Arthritis Rheum."},{"key":"2019111822324216400_B53","doi-asserted-by":"crossref","first-page":"786","DOI":"10.1136\/pgmj.58.686.786","article-title":"The Japanese plasma cell dyscrasia syndrome: case report and theory of pathogenesis.","volume":"58","author":"Tobin","year":"1982","journal-title":"Postgrad Med J."},{"key":"2019111822324216400_B54","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1136\/bmj.2.5455.203","article-title":"Peripheral sensorimotor neuropathy associated with a localized myeloma.","volume":"2","author":"Rushton","year":"1965","journal-title":"Br Med J."},{"key":"2019111822324216400_B55","first-page":"745","article-title":"Plasma cell dyscrasia with arteriopathy, polyneuropathy, and endocrine syndrome: a Japanese disease in an Italian patient [in French].","volume":"126","author":"Amiel","year":"1975","journal-title":"Ann Med Interne."},{"key":"2019111822324216400_B56","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1016\/S0894-7317(14)80451-3","article-title":"Aortic valvular fibroma as a source of systemic emboli in POEMS syndrome.","volume":"4","author":"Huth","year":"1991","journal-title":"J Am Soc Echocardiogr."},{"key":"2019111822324216400_B57","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1056\/NEJM198703053161008","article-title":"Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 10-1987. A 59-year-old woman with progressive polyneuropathy and monoclonal gammopathy.","volume":"316","year":"1987","journal-title":"N Engl J Med."},{"key":"2019111822324216400_B58","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1016\/0002-9343(79)90800-3","article-title":"Thrombocytosis, coronary thrombosis and acute myocardial infarction.","volume":"67","author":"Virmani","year":"1979","journal-title":"Am J Med."},{"key":"2019111822324216400_B59","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1046\/j.1365-2796.1996.498839000.x","article-title":"POEMS syndrome, arterial thrombosis and thrombocythaemia.","volume":"240","author":"Zenone","year":"1996","journal-title":"J Intern Med."},{"key":"2019111822324216400_B60","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1177\/000331979804901110","article-title":"POEMS syndrome with vascular lesions: a role for interleukin-1\u03b2 and interleukin-6 increase\u2014a case report.","volume":"49","author":"Bova","year":"1998","journal-title":"Angiology."},{"key":"2019111822324216400_B61","first-page":"170","article-title":"Crow-Fukase syndrome: a case associated with vasospastic angina.","volume":"16","author":"Mochizuki","year":"1994","journal-title":"Acta Neurol."},{"key":"2019111822324216400_B62","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1016\/0002-8703(92)90619-7","article-title":"Vasospastic angina in Crow-Fukase syndrome.","volume":"124","author":"Kato","year":"1992","journal-title":"Am Heart J."},{"key":"2019111822324216400_B63","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1136\/jnnp.63.3.385","article-title":"Long term melphalan-prednisolone chemotherapy for POEMS syndrome.","volume":"63","author":"Kuwabara","year":"1997","journal-title":"J Neurol Neurosurg Psychiatry."},{"key":"2019111822324216400_B64","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1016\/S0002-9394(98)00106-8","article-title":"POEMS syndrome: an unusual cause of bilateral optic disk swelling.","volume":"126","author":"Wong","year":"1998","journal-title":"Am J Ophthalmol."},{"key":"2019111822324216400_B65","first-page":"651","article-title":"An autopsy case of Crow-Fukase (POEMS) syndrome with a high level of IL-6 in the ascites: special reference to glomerular lesions.","volume":"42","author":"Nakazawa","year":"1992","journal-title":"Acta Pathol Jpn."},{"key":"2019111822324216400_B66","first-page":"1477","article-title":"Renal disease in POEMS syndrome: report on a case and review of the literature.","volume":"9","author":"Navis","year":"1994","journal-title":"Nephrol Dial Transplant."},{"key":"2019111822324216400_B67","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/0046-8177(89)90131-7","article-title":"Mesangiolytic glomerulonephritis associated with Takatsuki's syndrome: an analysis of five renal biopsy specimens.","volume":"20","author":"Nakamoto","year":"1989","journal-title":"Hum Pathol."},{"key":"2019111822324216400_B68","doi-asserted-by":"crossref","first-page":"2370","DOI":"10.1093\/ndt\/14.10.2370","article-title":"A spectrum of clinicopathological features of nephropathy associated with POEMS syndrome.","volume":"14","author":"Nakamoto","year":"1999","journal-title":"Nephrol Dial Transplant."},{"key":"2019111822324216400_B69","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1159\/000186994","article-title":"A case of POEMS syndrome showing elevated serum interleukin 6 and abnormal expression of interleukin 6 in the kidney.","volume":"62","author":"Fukatsu","year":"1992","journal-title":"Nephron."},{"key":"2019111822324216400_B70","first-page":"76","article-title":"The kidney disease of Crow-Fukase (POEMS) syndrome: a clinico-pathological study of four cases.","volume":"36","author":"Fukatsu","year":"1991","journal-title":"Clin Nephrol."},{"key":"2019111822324216400_B71","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1007\/BF00705402","article-title":"Glomerular lesions associated with the Crow-Fukase syndrome.","volume":"409","author":"Sano","year":"1986","journal-title":"Virchows Arch A Pathol Anat Histopathol."},{"key":"2019111822324216400_B72","first-page":"66","article-title":"Possible mechanism of progressive renal failure in Crow-Fukase syndrome.","volume":"47","author":"Takazoe","year":"1997","journal-title":"Clin Nephrol."},{"key":"2019111822324216400_B73","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1159\/000186536","article-title":"Renal involvement in POEMS syndrome.","volume":"59","author":"Mizuiri","year":"1991","journal-title":"Nephron."},{"key":"2019111822324216400_B74","first-page":"115","article-title":"Microangiopathic hypothesis of POEMS tissue lesions.","volume":"38","author":"Kubota","year":"1992","journal-title":"Clin Nephrol."},{"key":"2019111822324216400_B75","first-page":"342","article-title":"Renal involvement in POEMS syndrome.","volume":"43","author":"Modesto-Segonds","year":"1995","journal-title":"Clin Nephrol."},{"key":"2019111822324216400_B76","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1002\/art.1780290212","article-title":"POEMS syndrome: study of a patient with proteinuria, microangiopathic glomerulopathy, and renal enlargement.","volume":"29","author":"Fam","year":"1986","journal-title":"Arthritis Rheum."},{"key":"2019111822324216400_B77","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1159\/000116152","article-title":"Uncompacted lamellae in three patients with POEMS syndrome.","volume":"27","author":"Bergouignan","year":"1987","journal-title":"Eur Neurol."},{"key":"2019111822324216400_B78","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1136\/jnnp.64.6.809","article-title":"Ultrastructural characterisation of the M protein in nerve biopsy of patients with POEMS syndrome.","volume":"64","author":"Adams","year":"1998","journal-title":"J Neurol Neurosurg Psychiatry."},{"key":"2019111822324216400_B79","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/0303-8467(91)90061-S","article-title":"P.O.E.M.S. syndrome with complete recovery after treatment of a solitary plasmocytoma.","volume":"93","author":"Broussolle","year":"1991","journal-title":"Clin Neurol Neurosurg."},{"key":"2019111822324216400_B80","doi-asserted-by":"crossref","first-page":"64","DOI":"10.2169\/internalmedicine1962.30.64","article-title":"Crow-Fukase syndrome associated with extramedullary plasmacytoma.","volume":"30","author":"Shirabe","year":"1991","journal-title":"Jpn J Med."},{"key":"2019111822324216400_B81","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1111\/j.1600-0404.1989.tb03916.x","article-title":"The POEMS syndrome among Chinese: association with Castleman's disease and some immunological abnormalities.","volume":"80","author":"Thajeb","year":"1989","journal-title":"Acta Neurol Scand."},{"key":"2019111822324216400_B82","doi-asserted-by":"crossref","first-page":"932","DOI":"10.1046\/j.1365-2141.1999.1331e.x","article-title":"Human herpesvirus 8 infection, Castleman's disease and POEMS syndrome.","volume":"104","author":"Papo","year":"1999","journal-title":"Br J Haematol."},{"key":"2019111822324216400_B83","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1007\/BF00296746","article-title":"Uncompacted myelin lamellae in polyneuropathy, organomegaly, endocrinopathy, M-protein and skin changes syndrome: ultrastructural study of peripheral nerve biopsy from 22 patients.","volume":"87","author":"Vital","year":"1994","journal-title":"Acta Neuropathol."},{"key":"2019111822324216400_B84","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1097\/00000372-199806000-00008","article-title":"A case of glomeruloid hemangioma associated with multicentric Castleman's disease.","volume":"20","author":"Yang","year":"1998","journal-title":"Am J Dermatopathol."},{"key":"2019111822324216400_B85","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1097\/00000478-198510000-00008","article-title":"Plasma-cell dyscrasia with polyneuropathy and endocrine disorders associated with dysfunction of salivary glands.","volume":"9","author":"Kobayashi","year":"1985","journal-title":"Am J Surg Pathol."},{"key":"2019111822324216400_B86","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1002\/1097-0142(19850701)56:1<188::AID-CNCR2820560132>3.0.CO;2-Z","article-title":"Giant lymph node hyperplasia with osteoblastic bone lesions and the POEMS (Takatsuki's) syndrome.","volume":"56","author":"Bitter","year":"1985","journal-title":"Cancer."},{"key":"2019111822324216400_B87","first-page":"731","article-title":"Crow-Fukase syndrome (POEMS syndrome) and osseous mastocytosis secondary to Castleman's angiofollicular lymphoid hyperplasia [in French].","volume":"142","author":"Lapresle","year":"1986","journal-title":"Rev Neurol."},{"key":"2019111822324216400_B88","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1007\/BF00783029","article-title":"Pathological findings in three non-Japanese patients with the POEMS syndrome.","volume":"413","author":"Gherardi","year":"1988","journal-title":"Virchows Arch A Pathol Anat Histopathol."},{"key":"2019111822324216400_B89","first-page":"591","article-title":"Angiofollicular lymphatic hyperplasia with plasmacytoma and polyneuropathy: a case report with immunohistochemical study [in German].","volume":"66","author":"Dworak","year":"1988","journal-title":"Klin Wochenschr."},{"key":"2019111822324216400_B90","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1016\/S0344-0338(89)80064-0","article-title":"Multicentric angiofollicular lymph node hyperplasia associated with a solitary osteolytic costal IgG \u03bb myeloma. POEMS syndrome in a South American (Paraguayan) patient.","volume":"185","author":"Rolon","year":"1989","journal-title":"Pathol Res Pract."},{"key":"2019111822324216400_B91","first-page":"97","article-title":"Crow-Fukase syndrome (POEMS syndrome): the first Italian presentation of a case and review of the literature [in Italian].","volume":"125","author":"Carcaterra","year":"1990","journal-title":"G Ital Dermatol Venereol."},{"key":"2019111822324216400_B92","doi-asserted-by":"crossref","first-page":"1036","DOI":"10.1097\/00000478-199011000-00005","article-title":"Glomeruloid hemangioma: a distinctive cutaneous lesion of multicentric Castleman's disease associated with POEMS syndrome.","volume":"14","author":"Chan","year":"1990","journal-title":"Am J Surg Pathol."},{"key":"2019111822324216400_B93","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1111\/j.1365-2559.1990.tb00692.x","article-title":"Plasmacellular Castleman's disease and POEMS syndrome.","volume":"17","author":"Munoz","year":"1990","journal-title":"Histopathology."},{"key":"2019111822324216400_B94","doi-asserted-by":"crossref","first-page":"520","DOI":"10.7326\/0003-4819-114-6-520","article-title":"Castleman disease-POEMS syndrome overlap.","volume":"114","author":"Gherardi","year":"1991","journal-title":"Ann Intern Med."},{"key":"2019111822324216400_B95","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1016\/0002-9343(91)90644-D","article-title":"POEMS syndrome with idiopathic flushing mimicking carcinoid syndrome.","volume":"90","author":"Myers","year":"1991","journal-title":"Am J Med."},{"key":"2019111822324216400_B96","first-page":"416","article-title":"POEMS syndrome: an Italian case with diagnostic and therapeutic implications.","volume":"6","author":"Coto","year":"1991","journal-title":"Ann Ital Med Int."},{"key":"2019111822324216400_B97","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1111\/j.1445-5994.1991.tb01353.x","article-title":"POEMS syndrome, osteosclerotic myeloma and Castleman's disease: a case report.","volume":"21","author":"Bosco","year":"1991","journal-title":"Aust N Z J Med."},{"key":"2019111822324216400_B98","doi-asserted-by":"crossref","first-page":"2697","DOI":"10.1002\/1097-0142(19920601)69:11<2697::AID-CNCR2820691112>3.0.CO;2-3","article-title":"Castleman's disease in POEMS syndrome with elevated interleukin-6.","volume":"69","author":"Mandler","year":"1992","journal-title":"Cancer."},{"key":"2019111822324216400_B99","doi-asserted-by":"crossref","first-page":"874","DOI":"10.1002\/1097-0142(19930201)71:3<874::AID-CNCR2820710335>3.0.CO;2-#","article-title":"Castleman disease in POEMS syndrome with elevated interleukin-6 [letter].","volume":"71","author":"Emile","year":"1993","journal-title":"Cancer."},{"key":"2019111822324216400_B100","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1111\/j.1365-2230.1993.tb02218.x","article-title":"Angioendotheliomatosis associated with Castleman's lymphoma and POEMS syndrome.","volume":"18","author":"Judge","year":"1993","journal-title":"Clin Exp Dermatol."},{"key":"2019111822324216400_B101","doi-asserted-by":"crossref","first-page":"388","DOI":"10.2340\/0001555574388390","article-title":"POEMS syndrome and multiple angioproliferative lesions mimicking generalized histiocytomas.","volume":"74","author":"Del Rio","year":"1994","journal-title":"Acta Derm Venereol."},{"key":"2019111822324216400_B102","first-page":"751","article-title":"Angiofollicular lymphoid hyperplasia presenting as POEMS syndrome.","volume":"42","author":"Bhatia","year":"1994","journal-title":"J Assoc Physicians India."},{"key":"2019111822324216400_B103","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1097\/00000441-199402000-00008","article-title":"Case report: Castleman disease in association with POEMS.","volume":"307","author":"Adelman","year":"1994","journal-title":"Am J Med Sci."},{"key":"2019111822324216400_B104","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1007\/BF02339932","article-title":"The POEMS syndrome: report of six cases.","volume":"15","author":"Pareyson","year":"1994","journal-title":"Ital J Neurol Sci."},{"key":"2019111822324216400_B105","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1016\/S0003-9993(95)80643-1","article-title":"Severe polyneuropathy: initial manifestation of Castleman's disease associated with POEMS syndrome.","volume":"76","author":"Ku","year":"1995","journal-title":"Arch Phys Med Rehabil."},{"key":"2019111822324216400_B106","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1007\/BF00873980","article-title":"Poor response to intravenous immunoglobulin therapy in patients with Castleman's disease and the POEMS syndrome.","volume":"243","author":"Huang","year":"1996","journal-title":"J Neurol."},{"key":"2019111822324216400_B107","first-page":"366","article-title":"Intravenous immunoglobulin therapy in POEMS syndrome: a case report.","volume":"58","author":"Chang","year":"1996","journal-title":"Zhonghua Yi Xue Za Zhi."},{"key":"2019111822324216400_B108","first-page":"373","article-title":"POEMS syndrome (polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, skin changes), multicentric Castleman disease, renal chromophobe carcinoma and herpes virus type 8 infection [in French].","volume":"19","author":"Belec","year":"1999","journal-title":"Ann Pathol."},{"key":"2019111822324216400_B109","doi-asserted-by":"crossref","first-page":"3643","DOI":"10.1182\/blood.V93.11.3643","article-title":"Human herpesvirus 8 infection in patients with POEMS syndrome-associated multicentric Castleman's disease.","volume":"93","author":"Belec","year":"1999","journal-title":"Blood."},{"key":"2019111822324216400_B110","doi-asserted-by":"crossref","first-page":"678","DOI":"10.1086\/515169","article-title":"Antibodies to human herpesvirus 8 in POEMS (polyneuropathy, organomegaly, endocrinopathy, M protein, skin changes) syndrome with multicentric Castleman's disease.","volume":"28","author":"Belec","year":"1999","journal-title":"Clin Infect Dis."},{"key":"2019111822324216400_B111","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1093\/ajcp\/69.1.86","article-title":"Multicentric giant lymph node hyperplasia.","volume":"69","author":"Gaba","year":"1978","journal-title":"Am J Clin Pathol."},{"key":"2019111822324216400_B112","first-page":"379","article-title":"Angiofollicular lymph node hyperplasia and peripheral neuropathy: association with monoclonal gammopathy.","volume":"57","author":"Hineman","year":"1982","journal-title":"Mayo Clin Proc."},{"key":"2019111822324216400_B113","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1136\/pgmj.64.749.217","article-title":"Pseudotumour cerebri in a patient with Castleman's disease.","volume":"64","author":"Black","year":"1988","journal-title":"Postgrad Med J."},{"key":"2019111822324216400_B114","doi-asserted-by":"crossref","first-page":"362","DOI":"10.7326\/0003-4819-113-5-362","article-title":"Multicentric angiofollicular lymph node hyperplasia with peripheral neuropathy, pseudotumor cerebri, IgA dysproteinemia, and thrombocytosis in women: a distinct syndrome.","volume":"113","author":"Feigert","year":"1990","journal-title":"Ann Intern Med."},{"key":"2019111822324216400_B115","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1507\/endocrj.45.413","article-title":"Improvement in gonadotropin secretion after corticosteroid therapy in a case of POEMS syndrome.","volume":"45","author":"Sasano","year":"1998","journal-title":"Endocr J."},{"key":"2019111822324216400_B116","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1507\/endocrj.45.131","article-title":"Abnormal FSH hypersecretion as an endocrinological manifestation of POEMS syndrome.","volume":"45","author":"Shichiri","year":"1998","journal-title":"Endocr J."},{"key":"2019111822324216400_B117","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1007\/BF00320775","article-title":"Osteosclerotic myeloma with polyneuropathy and hypocalcemia.","volume":"58","author":"Ludescher","year":"1989","journal-title":"Blut."},{"key":"2019111822324216400_B118","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1016\/S0140-6736(96)91260-X","article-title":"Hypoparathyroidism in POEMS syndrome.","volume":"347","author":"Cabezas-Agricola","year":"1996","journal-title":"Lancet."},{"key":"2019111822324216400_B119","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1016\/S0002-9394(14)70678-6","article-title":"Optic disk swelling with peripheral neuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes (POEMS syndrome).","volume":"109","author":"Bolling","year":"1990","journal-title":"Am J Ophthalmol."},{"key":"2019111822324216400_B120","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1001\/archneur.1972.00490180043010","article-title":"Myeloma neuropathy: successful treatment of two patients and review of cases.","volume":"27","author":"Davis","year":"1972","journal-title":"Arch Neurol."},{"key":"2019111822324216400_B121","first-page":"2267","article-title":"Features of hypertrophic osteoarthropathy in patients with POEMS syndrome: a metaanalysis.","volume":"24","author":"Martinez-Lavin","year":"1997","journal-title":"J Rheumatol."},{"key":"2019111822324216400_B122","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/0303-8467(92)90122-J","article-title":"POEMS syndrome: follow-up study of a case.","volume":"94","author":"Crisci","year":"1992","journal-title":"Clin Neurol Neurosurg."},{"key":"2019111822324216400_B123","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1097\/00000372-199404000-00013","article-title":"Glomeruloid hemangioma: a cutaneous marker of POEMS syndrome.","volume":"16","author":"Rongioletti","year":"1994","journal-title":"Am J Dermatopathol."},{"key":"2019111822324216400_B124","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.1002\/mus.880170913","article-title":"The natural history of a \u201cbenign\u201d rib lesion in a patient with a demyelinating polyneuropathy and an unusual variant of POEMS syndrome.","volume":"17","author":"Simmons","year":"1994","journal-title":"Muscle Nerve."},{"key":"2019111822324216400_B125","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1002\/jca.2920020309","article-title":"Therapeutic trial of plasma exchange in osteosclerotic myeloma associated with the POEMS syndrome.","volume":"2","author":"Silberstein","year":"1985","journal-title":"J Clin Apheresis."},{"key":"2019111822324216400_B126","doi-asserted-by":"crossref","first-page":"1458","DOI":"10.1182\/blood.V87.4.1458.bloodjournal8741458","article-title":"Overproduction of proinflammatory cytokines imbalanced by their antagonists in POEMS syndrome.","volume":"87","author":"Gherardi","year":"1996","journal-title":"Blood."},{"key":"2019111822324216400_B127","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1002\/(SICI)1097-4598(199704)20:4<486::AID-MUS12>3.0.CO;2-X","article-title":"Coagulation and vascular abnormalities in Crow-Fukase syndrome.","volume":"20","author":"Saida","year":"1997","journal-title":"Muscle Nerve."},{"key":"2019111822324216400_B128","doi-asserted-by":"crossref","first-page":"1919","DOI":"10.1056\/NEJM199212313272705","article-title":"Plasma-cell dyscrasia with polyneuropathy: the spectrum of POEMS syndrome.","volume":"327","author":"Miralles","year":"1992","journal-title":"N Engl J Med."},{"key":"2019111822324216400_B129","doi-asserted-by":"crossref","first-page":"583","DOI":"10.2169\/internalmedicine.33.583","article-title":"Elevated serum interleukin-6 in POEMS syndrome reflects the activity of the disease.","volume":"33","author":"Hitoshi","year":"1994","journal-title":"Intern Med."},{"key":"2019111822324216400_B130","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1080\/01616412.1994.11740278","article-title":"POEMS syndrome: clinical, pathological and immunological study of a case.","volume":"16","author":"Orefice","year":"1994","journal-title":"Neurol Res."},{"key":"2019111822324216400_B131","doi-asserted-by":"crossref","first-page":"1620","DOI":"10.1002\/(SICI)1097-4598(199612)19:12<1620::AID-MUS16>3.0.CO;2-V","article-title":"Cytokines and myelin antibodies in Crow-Fukase syndrome.","volume":"19","author":"Saida","year":"1996","journal-title":"Muscle Nerve."},{"key":"2019111822324216400_B132","first-page":"103","article-title":"The effect of the radiation treatment on the polyneuropathy of multiple myeloma.","volume":"23","author":"Philips","year":"1972","journal-title":"J Can Assoc Radiol."},{"key":"2019111822324216400_B133","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1093\/ndt\/14.2.419","article-title":"Crow-Fukase syndrome: immunoadsorption plasmapheresis effectively lowers elevated interleukin-6 concentration.","volume":"14","author":"Ako","year":"1999","journal-title":"Nephrol Dial Transplant."},{"key":"2019111822324216400_B134","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1159\/000203980","article-title":"A case of Crow-Fukase syndrome with elevated soluble interleukin-6 receptor in cerebrospinal fluid: response to double-filtration plasmapheresis and corticosteroids.","volume":"94","author":"Atsumi","year":"1995","journal-title":"Acta Haematol."},{"key":"2019111822324216400_B135","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/S0022-510X(98)00107-5","article-title":"Rapidly deteriorating polyneuropathy associated with osteosclerotic myeloma responsive to intravenous immunoglobulin and radiotherapy.","volume":"158","author":"Benito-Leon","year":"1998","journal-title":"J Neurol Sci."},{"key":"2019111822324216400_B136","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1007\/BF00873555","article-title":"Combined high-dose 7S-IgG and dexamethasone is effective in severe polyneuropathy of the POEMS syndrome.","volume":"242","author":"Henze","year":"1995","journal-title":"J Neurol."},{"key":"2019111822324216400_B137","doi-asserted-by":"crossref","first-page":"1035","DOI":"10.1002\/(SICI)1097-4598(199708)20:8<1035::AID-MUS16>3.0.CO;2-U","article-title":"Marked improvement of severe polyneuropathy associated with multifocal osteosclerotic myeloma following surgery, radiation, and chemotherapy.","volume":"20","author":"Rotta","year":"1997","journal-title":"Muscle Nerve."},{"key":"2019111822324216400_B138","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1002\/mus.880070209","article-title":"Peripheral neuropathy in osteosclerotic myeloma: clinical and electrodiagnostic improvement with chemotherapy.","volume":"7","author":"Donofrio","year":"1984","journal-title":"Muscle Nerve."},{"key":"2019111822324216400_B139","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1007\/BF00618263","article-title":"Successful treatment of peripheral neuropathy with chemotherapy in osteosclerotic myeloma.","volume":"234","author":"Parra","year":"1987","journal-title":"J Neurol."},{"key":"2019111822324216400_B140","first-page":"102","article-title":"Polyneuropathy associated with osteosclerotic myeloma: excellent response to chemotherapy [in Spanish].","volume":"5","author":"Antela Lopez","year":"1990","journal-title":"Neurologia."},{"key":"2019111822324216400_B141","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/0014-2964(78)90171-8","article-title":"Osteosclerotic myeloma with polyneuropathy and ectopic secretion of calcitonin.","volume":"14","author":"Rousseau","year":"1978","journal-title":"Eur J Cancer."},{"key":"2019111822324216400_B142","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1212\/WNL.38.4.614","article-title":"Specific antibody activity against neuroendocrine tissue in a case of POEMS syndrome with IgG gammopathy.","volume":"38","author":"Reulecke","year":"1988","journal-title":"Neurology."},{"key":"2019111822324216400_B143","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1046\/j.1365-2141.2001.03040.x","article-title":"Dramatic improvement of POEMS syndrome following autologous haematopoietic cell transplantation.","volume":"115","author":"Rovira","year":"2001","journal-title":"Br J Haematol."},{"key":"2019111822324216400_B144","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1038\/sj.bmt.1703108","article-title":"Successful treatment of POEMS syndrome with autologous hematopoietic progenitor cell transplantation.","volume":"28","author":"Hogan","year":"2001","journal-title":"Bone Marrow Transplant."},{"key":"2019111822324216400_B145","first-page":"391b","article-title":"Peripheral blood stem cell transplant (PBSCT) in patients with POEMS syndrome [abstract].","volume":"98","author":"Dispenzieri","year":"2001","journal-title":"Blood."},{"key":"2019111822324216400_B146","doi-asserted-by":"crossref","first-page":"3057","DOI":"10.1182\/blood.V99.8.3057","article-title":"High-dose therapy and autologous blood stem cell transplantation in POEMS syndrome.","volume":"99","author":"Jaccard","year":"2002","journal-title":"Blood."}],"container-title":["Blood"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/ashpublications.org\/blood\/article-pdf\/101\/7\/2496\/1266372\/h80703002496.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/ashpublications.org\/blood\/article-pdf\/101\/7\/2496\/1266372\/h80703002496.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,11]],"date-time":"2024-12-11T06:13:17Z","timestamp":1733897597000},"score":1,"resource":{"primary":{"URL":"https:\/\/ashpublications.org\/blood\/article\/101\/7\/2496\/106657\/POEMS-syndrome-definitions-and-longterm"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,4,1]]},"references-count":146,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2003,4,1]]}},"URL":"https:\/\/doi.org\/10.1182\/blood-2002-07-2299","relation":{},"ISSN":["1528-0020","0006-4971"],"issn-type":[{"value":"1528-0020","type":"electronic"},{"value":"0006-4971","type":"print"}],"subject":[],"published":{"date-parts":[[2003,4,1]]}}}