{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T22:10:42Z","timestamp":1777414242261,"version":"3.51.4"},"reference-count":25,"publisher":"American Society of Hematology","issue":"10","content-domain":{"domain":["ashpublications.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2003,11,15]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The development of extranodal lymphomas is thought to be initiated by the transformation event in peripheral organs. Lymphomatoid papulosis (LyP) is a low-grade cutaneous lymphoma and may progress into the cutaneous anaplastic lymphoma. We identified 2 patients who 3 and 4 years before the development of LyP were treated for an unrelated malignancy (Burkitt lymphoma and small-cell B-cell lymphoma). We analyzed the T-cell receptor (TCR) gene rearrangement pattern in their skin, blood, and bone marrow, including the archival bone marrow sampled years before the development of clinically evident LyP. In all samples we detected the unique monoclonal TCR rearrangements. This observation suggests that the initial malignant transformation in LyP occurred in bone marrow and not, as could be supposed, in the skin. (Blood. 2003;102:3797-3799)<\/jats:p>","DOI":"10.1182\/blood-2003-03-0899","type":"journal-article","created":{"date-parts":[[2003,7,8]],"date-time":"2003-07-08T00:23:14Z","timestamp":1057623794000},"page":"3797-3799","update-policy":"https:\/\/doi.org\/10.1182\/blood.2019cm0000","source":"Crossref","is-referenced-by-count":34,"title":["Bone marrow precursor of extranodal T-cell lymphoma"],"prefix":"10.1182","volume":"102","author":[{"given":"Robert","family":"Gniadecki","sequence":"first","affiliation":[{"name":"From the Department of Dermatology, University of Copenhagen, Bispebjerg Hospital, Copenhagen, Denmark; Department of Dermatology, Humboldt University Charite\u0301, Berlin, Germany; Department of Pathology, University of Copenhagen, Bispebjerg Hospital, Copenhagen, Denmark; and Department of Clinical Immunology, The National University Hospital (Rigshospitalet), Copenhagen, Denmark."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ansgar","family":"Lukowsky","sequence":"additional","affiliation":[{"name":"From the Department of Dermatology, University of Copenhagen, Bispebjerg Hospital, Copenhagen, Denmark; Department of Dermatology, Humboldt University Charite\u0301, Berlin, Germany; Department of Pathology, University of Copenhagen, Bispebjerg Hospital, Copenhagen, Denmark; and Department of Clinical Immunology, The National University Hospital (Rigshospitalet), Copenhagen, Denmark."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kristian","family":"Rossen","sequence":"additional","affiliation":[{"name":"From the Department of Dermatology, University of Copenhagen, Bispebjerg Hospital, Copenhagen, Denmark; Department of Dermatology, Humboldt University Charite\u0301, Berlin, Germany; Department of Pathology, University of Copenhagen, Bispebjerg Hospital, Copenhagen, Denmark; and Department of Clinical Immunology, The National University Hospital (Rigshospitalet), Copenhagen, Denmark."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hans O.","family":"Madsen","sequence":"additional","affiliation":[{"name":"From the Department of Dermatology, University of Copenhagen, Bispebjerg Hospital, Copenhagen, Denmark; Department of Dermatology, Humboldt University Charite\u0301, Berlin, Germany; Department of Pathology, University of Copenhagen, Bispebjerg Hospital, Copenhagen, Denmark; and Department of Clinical Immunology, The National University Hospital (Rigshospitalet), Copenhagen, Denmark."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kristian","family":"Thomsen","sequence":"additional","affiliation":[{"name":"From the Department of Dermatology, University of Copenhagen, Bispebjerg Hospital, Copenhagen, Denmark; Department of Dermatology, Humboldt University Charite\u0301, Berlin, Germany; Department of Pathology, University of Copenhagen, Bispebjerg Hospital, Copenhagen, Denmark; and Department of Clinical Immunology, The National University Hospital (Rigshospitalet), Copenhagen, Denmark."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hans Christian","family":"Wulf","sequence":"additional","affiliation":[{"name":"From the Department of Dermatology, University of Copenhagen, Bispebjerg Hospital, Copenhagen, Denmark; Department of Dermatology, Humboldt University Charite\u0301, Berlin, Germany; Department of Pathology, University of Copenhagen, Bispebjerg Hospital, Copenhagen, Denmark; and Department of Clinical Immunology, The National University Hospital (Rigshospitalet), Copenhagen, Denmark."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"234","reference":[{"key":"2020021221591930700_REF1","doi-asserted-by":"crossref","unstructured":"Haase D, Feuring-Buske M, Konemann S, et al. 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