{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T01:47:23Z","timestamp":1792547243307,"version":"4.5.0"},"reference-count":64,"publisher":"American Society of Hematology","issue":"17","content-domain":{"domain":["ashpublications.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,4,28]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Glanzmann thrombasthenia (GT) is a rare inherited platelet function disorder caused by a quantitative and\/or qualitative defect of the \u03b1IIb\u03b23 integrin. Pregnancy and delivery are recognized risk periods for bleeding in women with GT. The newborn may also be affected by fetal and neonatal immune thrombocytopenia induced by the transplacental passage of maternal anti-\u03b1IIb\u03b23 antibodies, which can lead to severe hemorrhage and fetal loss. Pregnancy in women with GT thus requires a multidisciplinary approach, including prepregnancy counseling and a treatment plan for delivery for both the mother and child. In this article, we summarize the current knowledge on pregnancy in women with GT and describe how we manage this severe platelet disorder in our clinical practice.<\/jats:p>","DOI":"10.1182\/blood.2021011595","type":"journal-article","created":{"date-parts":[[2022,3,14]],"date-time":"2022-03-14T20:09:34Z","timestamp":1647288574000},"page":"2632-2641","update-policy":"https:\/\/doi.org\/10.1182\/blood.2019cm0000","source":"Crossref","is-referenced-by-count":29,"title":["How I manage pregnancy in women with Glanzmann thrombasthenia"],"prefix":"10.1182","volume":"139","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2526-8826","authenticated-orcid":false,"given":"Mathieu","family":"Fiore","sequence":"first","affiliation":[{"name":"Hematology Laboratory, Reference Center for Inherited Platelet Disorders, University Hospital of Bordeaux, Pessac, France;"},{"name":"Biology of Cardiovascular Diseases, INSERM U1034, Pessac, France;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lo\u00efc","family":"Sentilhes","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, University Hospital of Bordeaux, Pellegrin Hospital, Bordeaux, France;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4843-7805","authenticated-orcid":false,"given":"Roseline","family":"d\u2019Oiron","sequence":"additional","affiliation":[{"name":"Reference Center for Hemophilia and Other Rare Inherited Bleeding Disorders, Bic\u00eatre Hospital APHP, Le Kremlin-Bic\u00eatre, France; and"},{"name":"Hemostasis, Inflammation, and Thrombosis (HITh), UMR_S1176, INSERM, Paris-Saclay University, Le Kremlin-Bic\u00eatre, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"234","reference":[{"issue":"1","key":"2022042815223656200_B1","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1186\/1750-1172-1-10","article-title":"Glanzmann thrombasthenia","volume":"1","author":"Nurden","year":"2006","journal-title":"Orphanet J Rare Dis."},{"issue":"10","key":"2022042815223656200_B2","first-page":"20","article-title":"Clinical utility gene card for: Glanzmann thrombasthenia","volume":"20","author":"Fiore","year":"2012","journal-title":"Eur J Hum Genet."},{"issue":"5","key":"2022042815223656200_B3","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1002\/humu.22776","article-title":"Expanding the mutation spectrum affecting \u03b1IIb\u03b23 integrin in Glanzmann thrombasthenia: screening of the ITGA2B and ITGB3 genes in a large international cohort","volume":"36","author":"Nurden","year":"2015","journal-title":"Hum Mutat."},{"issue":"7","key":"2022042815223656200_B4","doi-asserted-by":"crossref","first-page":"1383","DOI":"10.1182\/blood.V75.7.1383.1383","article-title":"Glanzmann\u2019s thrombasthenia: the spectrum of clinical disease","volume":"75","author":"George","year":"1990","journal-title":"Blood."},{"issue":"6","key":"2022042815223656200_B5","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1055\/s-0033-1353393","article-title":"Glanzmann thrombasthenia: state of the art and future directions","volume":"39","author":"Nurden","year":"2013","journal-title":"Semin Thromb Hemost."},{"issue":"5","key":"2022042815223656200_B6","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1111\/bjh.15409","article-title":"How we treat the platelet glycoprotein defects: Glanzmann thrombasthenia and Bernard Soulier syndrome in children and adults","volume":"182","author":"Grainger","year":"2018","journal-title":"Br J Haematol."},{"issue":"2","key":"2022042815223656200_B7","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1111\/bjh.15087","article-title":"Anti-\u03b1IIb \u03b23 immunization in Glanzmann thrombasthenia: review of literature and treatment recommendations","volume":"181","author":"Fiore","year":"2018","journal-title":"Br J Haematol."},{"key":"2022042815223656200_B8","doi-asserted-by":"publisher","author":"Nurden","DOI":"10.1016\/j.tmrv.2018.05.002"},{"issue":"6","key":"2022042815223656200_B9","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1055\/s-0038-1648233","article-title":"Alloimmunization in congenital deficiencies of platelet surface glycoproteins: focus on Glanzmann\u2019s thrombasthenia and Bernard-Soulier\u2019s syndrome","volume":"44","author":"Poon","year":"2018","journal-title":"Semin Thromb Hemost."},{"key":"2022042815223656200_B10","author":"World-Federation-of-Haemophilia"},{"issue":"5","key":"2022042815223656200_B11","doi-asserted-by":"crossref","first-page":"e858","DOI":"10.1111\/j.1365-2516.2011.02516.x","article-title":"A systematic review of the management and outcomes of pregnancy in Glanzmann thrombasthenia","volume":"17","author":"Siddiq","year":"2011","journal-title":"Haemophilia."},{"issue":"4","key":"2022042815223656200_B12","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1111\/bjh.13458","article-title":"Analysis of 65 pregnancies in 34 women with five different forms of inherited platelet function disorders","volume":"170","author":"Civaschi","year":"2015","journal-title":"Br J Haematol."},{"issue":"6","key":"2022042815223656200_B13","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1586\/17474086.2014.980811","article-title":"NovoSeven (recombinant factor VIIa) for the treatment of bleeding episodes and perioperative management in patients with Glanzmann\u2019s thrombasthenia","volume":"7","author":"Franchini","year":"2014","journal-title":"Expert Rev Hematol."},{"issue":"2","key":"2022042815223656200_B14","doi-asserted-by":"crossref","first-page":"337","DOI":"10.3324\/haematol.2020.248153","article-title":"Inherited platelet diseases with normal platelet count: phenotypes, genotypes and diagnostic strategy","volume":"106","author":"Nurden","year":"2021","journal-title":"Haematologica."},{"issue":"1","key":"2022042815223656200_B15","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1046\/j.1365-2141.1996.d01-1888.x","article-title":"Autoantibodies and anti-mouse antibodies in thrombocytopenic patients as assessed by different MAIPA assays","volume":"95","author":"Clofent-Sanchez","year":"1996","journal-title":"Br J Haematol."},{"issue":"8","key":"2022042815223656200_B16","first-page":"1038","article-title":"The international, prospective Glanzmann Thrombasthenia Registry: treatment and outcomes in surgical intervention","volume":"100","author":"Poon","year":"2015","journal-title":"Haematologica."},{"issue":"3","key":"2022042815223656200_B17","doi-asserted-by":"crossref","first-page":"e201","DOI":"10.1111\/j.1365-2516.2011.02744.x","article-title":"Natural history of platelet antibody formation against \u03b1IIb\u03b23 in a French cohort of Glanzmann thrombasthenia patients","volume":"18","author":"Fiore","year":"2012","journal-title":"Haemophilia."},{"issue":"1","key":"2022042815223656200_B18","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1007\/s12185-010-0731-5","article-title":"Molecular analysis of a patient with type I Glanzmann thrombasthenia and clinical impact of the presence of anti-\u03b1IIb\u03b23 alloantibodies","volume":"93","author":"Kashiwagi","year":"2011","journal-title":"Int J Hematol."},{"issue":"8","key":"2022042815223656200_B19","doi-asserted-by":"crossref","first-page":"1866","DOI":"10.1111\/j.1538-7836.2010.03920.x","article-title":"Mutation analysis for a patient with Glanzmann thrombasthenia who produced a landmark isoantibody to the \u03b1IIb\u03b23 integrin","volume":"8","author":"Nurden","year":"2010","journal-title":"J Thromb Haemost."},{"issue":"12","key":"2022042815223656200_B20","doi-asserted-by":"crossref","first-page":"e27376","DOI":"10.1002\/pbc.27376","article-title":"From thrombasthenia to next generation thrombocytopenia: neonatal alloimmune thrombocytopenia induced by maternal Glanzmann thrombasthenia","volume":"65","author":"Barg","year":"2018","journal-title":"Pediatr Blood Cancer."},{"issue":"4","key":"2022042815223656200_B21","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1177\/1753495X16655021","article-title":"Glanzmann thrombasthenia in pregnancy: optimising maternal and fetal outcomes","volume":"9","author":"Wijemanne","year":"2016","journal-title":"Obstet Med."},{"issue":"2","key":"2022042815223656200_B22","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1111\/hae.13927","article-title":"Menstrual and obstetrical bleeding in women with inherited platelet receptor defects: a systematic review","volume":"26","author":"Punt","year":"2020","journal-title":"Haemophilia."},{"issue":"4","key":"2022042815223656200_B23","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1111\/bjh.16419","article-title":"Maternal antibodies against paternal class I human leukocyte antigens are not associated with foetal and neonatal alloimmune thrombocytopenia","volume":"189","author":"Sachs","year":"2020","journal-title":"Br J Haematol."},{"issue":"6","key":"2022042815223656200_B24","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1007\/s12185-021-03092-z","article-title":"Down syndrome with neonatal alloimmune thrombocytopenia due to anti-HLA A31 and B61 antibodies","volume":"113","author":"Shima","year":"2021","journal-title":"Int J Hematol."},{"issue":"2","key":"2022042815223656200_B25","first-page":"262","article-title":"Immunisation against \u03b1IIb\u03b23 and \u03b1v\u03b23 in a type 1 variant of Glanzmann\u2019s thrombasthenia caused by a missense mutation Gly540Asp on \u03b23","volume":"116","author":"Wihadmadyatami","year":"2016","journal-title":"Thromb Haemost."},{"issue":"8","key":"2022042815223656200_B26","doi-asserted-by":"crossref","first-page":"1517","DOI":"10.1161\/ATVBAHA.116.307281","article-title":"Antiendothelial \u03b1v\u03b23 antibodies are a major cause of intracranial bleeding in fetal\/neonatal alloimmune thrombocytopenia","volume":"36","author":"Santoso","year":"2016","journal-title":"Arterioscler Thromb Vasc Biol."},{"issue":"1","key":"2022042815223656200_B27","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1111\/jth.15117","article-title":"Immunization against \u03b1IIb \u03b23 and \u03b1v \u03b23 in Glanzmann thrombasthenia patients carrying the French Gypsy mutation","volume":"19","author":"Fiore","year":"2021","journal-title":"J Thromb Haemost."},{"issue":"1","key":"2022042815223656200_B28","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1002\/rth2.12281","article-title":"Congenital platelet disorders and health status\u2013related quality of life","volume":"4","author":"Blaauwgeers","year":"2020","journal-title":"Res Pract Thromb Haemost"},{"issue":"6","key":"2022042815223656200_B29","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.1160\/TH09-04-0225","article-title":"Glanzmann\u2019s thrombasthenia (defective platelet integrin alphaIIb-beta3): proposals for management between evidence and open issues","volume":"102","author":"Di Minno","year":"2009","journal-title":"Thromb Haemost."},{"issue":"3","key":"2022042815223656200_B30","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1055\/s-0040-1718373","article-title":"The use of recombinant activated factor VII in patients with Glanzmann\u2019s thrombasthenia","volume":"121","author":"Poon","year":"2021","journal-title":"Thromb Haemost."},{"issue":"6","key":"2022042815223656200_B31","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1111\/j.1365-2141.2010.08191.x","article-title":"Modern management of severe platelet function disorders","volume":"149","author":"Alamelu","year":"2010","journal-title":"Br J Haematol."},{"issue":"8","key":"2022042815223656200_B32","first-page":"1031","article-title":"The international, prospective Glanzmann Thrombasthenia Registry: treatment modalities and outcomes of non-surgical bleeding episodes in patients with Glanzmann thrombasthenia","volume":"100","author":"Di Minno","year":"2015","journal-title":"Haematologica."},{"issue":"2","key":"2022042815223656200_B33","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/j.tmrv.2016.01.001","article-title":"New insights into the treatment of Glanzmann thrombasthenia","volume":"30","author":"Poon","year":"2016","journal-title":"Transfus Med Rev."},{"issue":"5","key":"2022042815223656200_B34","doi-asserted-by":"crossref","first-page":"e380","DOI":"10.1111\/j.1365-2516.2012.02873.x","article-title":"Successful in\u00a0vitro fertilization and pregnancy in Glanzmann thrombasthenia","volume":"18","author":"Domschke","year":"2012","journal-title":"Haemophilia."},{"issue":"6","key":"2022042815223656200_B35","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1016\/j.jogoh.2019.03.014","article-title":"Intraventricular hemorrhage in ICSI twin pregnant woman with thrombasthenia: a rare case report","volume":"48","author":"Ali","year":"2019","journal-title":"J Gynecol Obstet Hum Reprod."},{"issue":"2","key":"2022042815223656200_B36","doi-asserted-by":"crossref","first-page":"273","DOI":"10.3109\/01443615.2015.1060198","article-title":"Live birth following an intracytoplasmic sperm injection in a patient with Glanzmann thrombasthenia","volume":"36","author":"Bozkurt","year":"2016","journal-title":"J Obstet Gynaecol."},{"key":"2022042815223656200_B37","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/hae.12269","article-title":"Pregnancy complications and obstetric care in women with inherited bleeding disorders","volume":"19","author":"Kadir","year":"2013","journal-title":"Haemophilia."},{"issue":"1","key":"2022042815223656200_B38","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.bpobgyn.2011.10.005","article-title":"Inherited bleeding disorders in pregnancy","volume":"26","author":"Chi","year":"2012","journal-title":"Best Pract Res Clin Obstet Gynaecol."},{"issue":"1","key":"2022042815223656200_B39","first-page":"40","article-title":"Antibody removal therapy used successfully at delivery of a pregnant patient with Glanzmann\u2019s thrombasthenia and multiple anti-platelet antibodies","volume":"61","author":"Ito","year":"1991","journal-title":"Vox Sang."},{"issue":"4","key":"2022042815223656200_B40","first-page":"507","article-title":"Glanzmann\u2019s thrombasthenia and pregnancy. Contribution of plasma exchange before scheduled cesarean section","volume":"18","author":"Vivier","year":"1989","journal-title":"J Gynecol Obstet Biol Reprod (Paris)."},{"key":"2022042815223656200_B41","first-page":"1154","article-title":"Glanzmann thrombasthenia and pregnancy: clinical observations and management of four affected women [abstract]","author":"Boval","year":"2001","journal-title":"Thromb Haemost."},{"issue":"3","key":"2022042815223656200_B42","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1111\/j.1447-0756.1997.tb00839.x","article-title":"Pregnancy in a patient of Glanzmann\u2019s thrombasthenia with antiplatelet antibodies","volume":"23","author":"Kashyap","year":"1997","journal-title":"J Obstet Gynaecol Res."},{"issue":"5","key":"2022042815223656200_B43","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1093\/bja\/88.5.734","article-title":"Peripartum management of a patient with Glanzmann\u2019s thrombasthenia using Thrombelastograph","volume":"88","author":"Monte","year":"2002","journal-title":"Br J Anaesth."},{"issue":"4","key":"2022042815223656200_B44","first-page":"256","article-title":"Glanzmann\u2019s thrombasthenia and pregnancy","volume":"39","author":"Walters","year":"1990","journal-title":"West Indian Med J."},{"issue":"3","key":"2022042815223656200_B45","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1111\/bjh.15813","article-title":"Fetal and neonatal alloimmune thrombocytopenia: recommendations for evidence-based practice, an international approach","volume":"185","author":"Lieberman","year":"2019","journal-title":"Br J Haematol."},{"issue":"3","key":"2022042815223656200_B46","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1055\/s-0038-1661184","article-title":"A Glanzmann\u2019s thrombasthenia cluster among Iraqi Jews in Israel","volume":"52","author":"Seligsohn","year":"1984","journal-title":"Thromb Haemost."},{"issue":"3","key":"2022042815223656200_B47","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1111\/j.1600-0609.1983.tb01477.x","article-title":"Increased incidence of Glanzmann\u2019s thrombasthenia in Jordan as compared with Scandinavia","volume":"30","author":"Awidi","year":"1983","journal-title":"Scand J Haematol."},{"issue":"4","key":"2022042815223656200_B48","first-page":"207","article-title":"Prenatal diagnosis of Glanzmann thrombasthenia","volume":"16","author":"Srivastava","year":"2003","journal-title":"Natl Med J India."},{"issue":"3","key":"2022042815223656200_B49","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1016\/S0950-3536(89)80034-4","article-title":"Prenatal diagnosis of platelet disorders","volume":"2","author":"Wautier","year":"1989","journal-title":"Baillieres Clin Haematol."},{"issue":"8469-70","key":"2022042815223656200_B50","doi-asserted-by":"crossref","first-page":"1419","DOI":"10.1016\/S0140-6736(85)92579-6","article-title":"Prenatal diagnosis of Glanzmann\u2019s thrombasthenia","volume":"2","author":"Seligsohn","year":"1985","journal-title":"Lancet."},{"issue":"2","key":"2022042815223656200_B51","doi-asserted-by":"crossref","first-page":"e99","DOI":"10.1111\/hae.12865","article-title":"Second trimester prenatal diagnosis in Glanzmann\u2019s thrombasthenia","volume":"22","author":"Kulkarni","year":"2016","journal-title":"Haemophilia."},{"issue":"3","key":"2022042815223656200_B52","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1097\/AOG.0000000000001000","article-title":"Maternal and neonatal morbidity after attempted operative vaginal delivery according to fetal head station","volume":"126","author":"Ducarme","year":"2015","journal-title":"Obstet Gynecol."},{"issue":"1","key":"2022042815223656200_B53","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.ejogrb.2011.06.043","article-title":"Instrumental delivery: clinical practice guidelines from the French College of Gynaecologists and Obstetricians","volume":"159","author":"Vayssi\u00e8re","year":"2011","journal-title":"Eur J Obstet Gynecol Reprod Biol."},{"issue":"11","key":"2022042815223656200_B54","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1080\/17474086.2016.1245135","article-title":"Postpartum haemorrhage: prevention and treatment","volume":"9","author":"Sentilhes","year":"2016","journal-title":"Expert Rev Hematol."},{"issue":"5","key":"2022042815223656200_B55","doi-asserted-by":"crossref","first-page":"718","DOI":"10.1111\/1471-0528.14305","article-title":"Comparison of postpartum haemorrhage guidelines: discrepancies underline our lack of knowledge","volume":"124","author":"Sentilhes","year":"2017","journal-title":"BJOG."},{"issue":"8","key":"2022042815223656200_B56","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1056\/NEJMoa1800942","article-title":"Tranexamic acid for the prevention of blood loss after vaginal delivery","volume":"379","author":"Sentilhes","year":"2018","journal-title":"N Engl J Med."},{"issue":"9","key":"2022042815223656200_B57","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1080\/17474086.2019.1642744","article-title":"Tranexamic acid for childbirth: why, when, and for whom","volume":"12","author":"Sentilhes","year":"2019","journal-title":"Expert Rev Hematol."},{"issue":"4","key":"2022042815223656200_B58","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1093\/bja\/aeu448","article-title":"Tranexamic acid for the prevention and treatment of postpartum haemorrhage","volume":"114","author":"Sentilhes","year":"2015","journal-title":"Br J Anaesth."},{"issue":"17","key":"2022042815223656200_B59","doi-asserted-by":"crossref","first-page":"1623","DOI":"10.1056\/NEJMoa2028788","article-title":"Tranexamic acid for the prevention of blood loss after cesarean delivery","volume":"384","author":"Sentilhes","year":"2021","journal-title":"N Engl J Med."},{"issue":"6","key":"2022042815223656200_B60","doi-asserted-by":"crossref","first-page":"906","DOI":"10.1111\/hae.13067","article-title":"Obstetric bleeding among women with inherited bleeding disorders: a retrospective study","volume":"22","author":"Hawke","year":"2016","journal-title":"Haemophilia."},{"issue":"10084","key":"2022042815223656200_B61","doi-asserted-by":"crossref","first-page":"2105","DOI":"10.1016\/S0140-6736(17)30638-4","article-title":"Effect of early tranexamic acid administration on mortality, hysterectomy, and other morbidities in women with post-partum haemorrhage (WOMAN): an international, randomised, double-blind, placebo-controlled trial","volume":"389","author":"WOMAN Trial Collaborators","year":"2017","journal-title":"Lancet."},{"key":"2022042815223656200_B62","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.ejogrb.2015.12.012","article-title":"Postpartum hemorrhage: guidelines for clinical practice from the French College of Gynaecologists and Obstetricians (CNGOF): in collaboration with the French Society of Anesthesiology and Intensive Care (SFAR)","volume":"198","author":"Sentilhes","year":"2016","journal-title":"Eur J Obstet Gynecol Reprod Biol."},{"issue":"6","key":"2022042815223656200_B63","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1097\/MOH.0000000000000608","article-title":"Platelet transfusion for patients with platelet dysfunction: effectiveness, mechanisms, and unanswered questions","volume":"27","author":"Lee","year":"2020","journal-title":"Curr Opin Hematol."},{"issue":"522","key":"2022042815223656200_B64","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1126\/scitranslmed.aay0203","article-title":"Impaired hemostatic activity of healthy transfused platelets in inherited and acquired platelet disorders: mechanisms and implications","volume":"11","author":"Lee","year":"2019","journal-title":"Sci Transl Med."}],"container-title":["Blood"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/ashpublications.org\/blood\/article-pdf\/139\/17\/2632\/1894741\/bloodbld2021011595c.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/ashpublications.org\/blood\/article-pdf\/139\/17\/2632\/1894741\/bloodbld2021011595c.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,18]],"date-time":"2023-11-18T20:43:40Z","timestamp":1700340220000},"score":1,"resource":{"primary":{"URL":"https:\/\/ashpublications.org\/blood\/article\/139\/17\/2632\/484395\/How-I-manage-pregnancy-in-women-with-Glanzmann"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4,28]]},"references-count":64,"journal-issue":{"issue":"17","published-print":{"date-parts":[[2022,4,28]]}},"URL":"https:\/\/doi.org\/10.1182\/blood.2021011595","relation":{},"ISSN":["0006-4971","1528-0020"],"issn-type":[{"value":"0006-4971","type":"print"},{"value":"1528-0020","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,4,28]]}}}