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However, we conclusively demonstrate late relapse can evolve from a pre-leukemic subclone harbouring a non-coding mutation that evades initial chemotherapy.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1182\/blood.2023021906","type":"journal-article","created":{"date-parts":[[2024,1,9]],"date-time":"2024-01-09T22:07:41Z","timestamp":1704838061000},"page":"933-937","update-policy":"https:\/\/doi.org\/10.1182\/blood.2019cm0000","source":"Crossref","is-referenced-by-count":9,"title":["Noncoding mutations drive persistence of a founder preleukemic clone which initiates late relapse in T-ALL"],"prefix":"10.1182","volume":"143","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3542-5976","authenticated-orcid":false,"given":"David","family":"O\u2019Connor","sequence":"first","affiliation":[{"name":"1UCL Cancer Institute, University College London, London, United Kingdom"},{"name":"2Department of Haematology, Great Ormond Street Hospital for Children, London, United 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