{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,25]],"date-time":"2026-04-25T14:08:34Z","timestamp":1777126114586,"version":"3.51.4"},"reference-count":49,"publisher":"American Society of Hematology","issue":"2","license":[{"start":{"date-parts":[[2024,4,15]],"date-time":"2024-04-15T00:00:00Z","timestamp":1713139200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["ashpublications.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,7,11]]},"abstract":"<jats:sec>\n                  <jats:title>Abstract<\/jats:title>\n                  <jats:p>SRY-related HMG-box gene 11 (SOX11) is a transcription factor overexpressed in mantle cell lymphoma (MCL), a subset of Burkitt lymphomas (BL) and precursor lymphoid cell neoplasms but is absent in normal B cells and other B-cell lymphomas. SOX11 has an oncogenic role in MCL but its contribution to BL pathogenesis remains uncertain. Here, we observed that the presence of Epstein-Barr virus (EBV) and SOX11 expression were mutually exclusive in BL. SOX11 expression in EBV-negative (EVB-) BL was associated with an IG\u2237MYC translocation generated by aberrant class switch recombination, whereas in EBV-negative (EBV\u2212)\/SOX11-negative (SOX11\u2212) tumors the IG\u2237MYC translocation was mediated by mistaken somatic hypermutations. Interestingly, EBV\u2212 SOX11-expressing BL showed higher frequency of SMARCA4 and ID3 mutations than EBV\u2212\/SOX11\u2212 cases. By RNA sequencing, we identified a SOX11\u2013associated gene expression profile, with functional annotations showing partial overlap with the SOX11 transcriptional program of MCL. Contrary to MCL, no differences on cell migration or B-cell receptor signaling were found between SOX11\u2212 and SOX11-positive (SOX11+) BL cells. However, SOX11+ BL showed higher adhesion to vascular\u00a0cell adhesion molecule\u00a01\u00a0(VCAM-1) than SOX11\u2212 BL cell lines. Here, we demonstrate that EBV\u2212 BL comprises 2 subsets of cases based on SOX11 expression. The mutual exclusion of SOX11 and EBV, and the association of SOX11 with a specific genetic landscape suggest a role of SOX11 in the early pathogenesis of BL.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1182\/blood.2023023242","type":"journal-article","created":{"date-parts":[[2024,4,15]],"date-time":"2024-04-15T18:11:14Z","timestamp":1713204674000},"page":"187-200","update-policy":"https:\/\/doi.org\/10.1182\/blood.2019cm0000","source":"Crossref","is-referenced-by-count":17,"title":["SOX11 expression is restricted to EBV-negative Burkitt lymphoma and is associated with molecular genetic features"],"prefix":"10.1182","volume":"144","author":[{"given":"Marta","family":"Sureda-G\u00f3mez","sequence":"first","affiliation":[{"name":"1Institut d'Investigacions Biom\u00e8diques August Pi i Sunyer, Barcelona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7324-993X","authenticated-orcid":false,"given":"Ingram","family":"Iaccarino","sequence":"additional","affiliation":[{"name":"2Department of Pathology, Hematopathology Section and Lymph Node Registry, University of Kiel, Kiel, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3627-9926","authenticated-orcid":false,"given":"Anna","family":"De Bol\u00f2s","sequence":"additional","affiliation":[{"name":"1Institut d'Investigacions Biom\u00e8diques August Pi i Sunyer, Barcelona, Spain"},{"name":"3Centro de Investigaci\u00f3n Biom\u00e9dica en Red-Oncolog\u00eda, Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8458-9737","authenticated-orcid":false,"given":"Mieke","family":"Meyer","sequence":"additional","affiliation":[{"name":"2Department of Pathology, Hematopathology Section and Lymph Node Registry, University of Kiel, Kiel, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patricia","family":"Balsas","sequence":"additional","affiliation":[{"name":"1Institut d'Investigacions Biom\u00e8diques August Pi i Sunyer, Barcelona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julia","family":"Richter","sequence":"additional","affiliation":[{"name":"2Department of Pathology, Hematopathology Section and Lymph Node Registry, University of Kiel, Kiel, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marta-Leonor","family":"Rodr\u00edguez","sequence":"additional","affiliation":[{"name":"1Institut d'Investigacions Biom\u00e8diques August Pi i Sunyer, Barcelona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cristina","family":"L\u00f3pez","sequence":"additional","affiliation":[{"name":"1Institut d'Investigacions Biom\u00e8diques August Pi i Sunyer, Barcelona, Spain"},{"name":"3Centro de Investigaci\u00f3n Biom\u00e9dica en Red-Oncolog\u00eda, Madrid, Spain"},{"name":"4Institute of Human Genetics, Ulm University and Ulm University Medical Center, Ulm, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-1182-9138","authenticated-orcid":false,"given":"Maria","family":"Carreras-Caball\u00e9","sequence":"additional","affiliation":[{"name":"1Institut d'Investigacions Biom\u00e8diques August Pi i Sunyer, Barcelona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Selina","family":"Glaser","sequence":"additional","affiliation":[{"name":"4Institute of Human Genetics, Ulm University and Ulm University Medical Center, Ulm, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2910-9440","authenticated-orcid":false,"given":"Ferran","family":"Nadeu","sequence":"additional","affiliation":[{"name":"1Institut d'Investigacions Biom\u00e8diques August Pi i Sunyer, Barcelona, Spain"},{"name":"3Centro de Investigaci\u00f3n Biom\u00e9dica en Red-Oncolog\u00eda, Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pedro","family":"Jares","sequence":"additional","affiliation":[{"name":"1Institut d'Investigacions Biom\u00e8diques August Pi i Sunyer, Barcelona, Spain"},{"name":"3Centro de Investigaci\u00f3n Biom\u00e9dica en Red-Oncolog\u00eda, Madrid, Spain"},{"name":"5Department of Hematology Hospital Clinic of Barcelona, Barcelona, Spain"},{"name":"6University of Barcelona, Barcelona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2588-7413","authenticated-orcid":false,"given":"Guillem","family":"Clot","sequence":"additional","affiliation":[{"name":"1Institut d'Investigacions Biom\u00e8diques August Pi i Sunyer, Barcelona, Spain"},{"name":"3Centro de Investigaci\u00f3n Biom\u00e9dica en Red-Oncolog\u00eda, Madrid, Spain"},{"name":"6University of Barcelona, Barcelona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Chiara","family":"Siciliano","sequence":"additional","affiliation":[{"name":"7Department of Medical Biotechnologies, Section of Pathological Anatomy, University of Siena, Siena, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6119-9007","authenticated-orcid":false,"given":"Cristiana","family":"Bellan","sequence":"additional","affiliation":[{"name":"7Department of Medical Biotechnologies, Section of Pathological Anatomy, University of Siena, Siena, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Salvatore","family":"Tornamb\u00e8","sequence":"additional","affiliation":[{"name":"7Department of Medical Biotechnologies, Section of Pathological Anatomy, University of Siena, Siena, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roberto","family":"Boccacci","sequence":"additional","affiliation":[{"name":"7Department of Medical Biotechnologies, Section of Pathological Anatomy, University of Siena, Siena, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lorenzo","family":"Leoncini","sequence":"additional","affiliation":[{"name":"7Department of Medical Biotechnologies, Section of Pathological Anatomy, University of Siena, Siena, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9850-9793","authenticated-orcid":false,"given":"Elias","family":"Campo","sequence":"additional","affiliation":[{"name":"1Institut d'Investigacions Biom\u00e8diques August Pi i Sunyer, Barcelona, Spain"},{"name":"3Centro de Investigaci\u00f3n Biom\u00e9dica en Red-Oncolog\u00eda, Madrid, Spain"},{"name":"5Department of Hematology Hospital Clinic of Barcelona, Barcelona, Spain"},{"name":"6University of Barcelona, Barcelona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reiner","family":"Siebert","sequence":"additional","affiliation":[{"name":"4Institute of Human Genetics, Ulm University and Ulm University Medical Center, Ulm, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Virginia","family":"Amador","sequence":"additional","affiliation":[{"name":"1Institut d'Investigacions Biom\u00e8diques August Pi i Sunyer, Barcelona, Spain"},{"name":"3Centro de Investigaci\u00f3n Biom\u00e9dica en Red-Oncolog\u00eda, Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7208-4117","authenticated-orcid":false,"given":"Wolfram","family":"Klapper","sequence":"additional","affiliation":[{"name":"2Department of Pathology, Hematopathology Section and Lymph Node Registry, University of Kiel, Kiel, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"234","reference":[{"key":"2024071115211573200_bib1","first-page":"285","volume-title":"WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues","author":"Swerdlow","year":"2017","edition":"4th ed."},{"issue":"1","key":"2024071115211573200_bib2","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1038\/leu.2010.245","article-title":"Non-Hodgkin\u2019s lymphoma in adolescents: experiences in 378 adolescent NHL patients\u00a0treated according to pediatric NHL-BFM protocols","volume":"25","author":"Burkhardt","year":"2011","journal-title":"Leukemia"},{"issue":"6","key":"2024071115211573200_bib3","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1111\/j.1365-2141.2011.09024.x","article-title":"Risk factors and treatment of childhood and adolescent Burkitt lymphoma\/leukaemia","volume":"156","author":"Miles","year":"2012","journal-title":"Br J Haematol"},{"issue":"6","key":"2024071115211573200_bib4","doi-asserted-by":"crossref","first-page":"345","DOI":"10.3322\/canjclin.22.6.349","article-title":"Classics in oncology. a sarcoma\u00a0involving the jaws in African children","volume":"22","author":"Burkitt","year":"1972","journal-title":"CA Cancer J Clin"},{"issue":"9","key":"2024071115211573200_bib5","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1016\/S0002-9343(01)01020-8","article-title":"Human immunodeficiency virus-related lymphoma: relation between clinical features and histologic subtypes","volume":"111","author":"Gabarre","year":"2001","journal-title":"Am J Med"},{"issue":"2","key":"2024071115211573200_bib6","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1097\/PAS.0000000000000332","article-title":"Epstein-Barr virus (EBV)-positive sporadic Burkitt lymphoma: an age-related lymphoproliferative disorder?","volume":"39","author":"Satou","year":"2015","journal-title":"Am J Surg Pathol"},{"issue":"3","key":"2024071115211573200_bib7","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1111\/bjh.17874","article-title":"Epstein\u2013Barr virus status of sporadic Burkitt lymphoma is associated with patient age and mutational features","volume":"196","author":"Richter","year":"2022","journal-title":"Br J Haematol"},{"issue":"1","key":"2024071115211573200_bib8","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1002\/ijc.2910170108","article-title":"Characteristic chromosomal abnormalities in biopsies and lymphoid-cell lines from patients with Burkitt and non-Burkitt lymphomas","volume":"17","author":"Zech","year":"1976","journal-title":"Int J Cancer"},{"issue":"2","key":"2024071115211573200_bib9","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1038\/leu.2008.281","article-title":"Translocations involving 8q24 in Burkitt lymphoma and other malignant lymphomas: a historical review of cytogenetics in the light of todays knowledge","volume":"23","author":"Boerma","year":"2009","journal-title":"Leukemia"},{"issue":"1","key":"2024071115211573200_bib10","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1111\/j.1749-6632.1987.tb36249.x","article-title":"Mechanism of activation and biological role of the c-myc oncogene in B-cell lymphomagenesis","volume":"511","author":"Dalla-Favera","year":"1987","journal-title":"Ann N Y Acad Sci"},{"issue":"2","key":"2024071115211573200_bib11","doi-asserted-by":"crossref","first-page":"a014282","DOI":"10.1101\/cshperspect.a014282","article-title":"Oncogenic mechanisms in Burkitt lymphoma","volume":"4","author":"Schmitz","year":"2014","journal-title":"Cold Spring Harb Perspect Med"},{"issue":"2","key":"2024071115211573200_bib12","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/j.ccr.2012.06.012","article-title":"Synergy between PI3K signaling and MYC in Burkitt lymphomagenesis","volume":"22","author":"Sander","year":"2012","journal-title":"Cancer Cell"},{"issue":"7418","key":"2024071115211573200_bib13","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1038\/nature11378","article-title":"Burkitt lymphoma pathogenesis and therapeutic targets from structural and functional genomics","volume":"490","author":"Schmitz","year":"2012","journal-title":"Nature"},{"issue":"12","key":"2024071115211573200_bib14","doi-asserted-by":"crossref","first-page":"1321","DOI":"10.1038\/ng.2468","article-title":"The genetic landscape of mutations in Burkitt lymphoma","volume":"44","author":"Love","year":"2012","journal-title":"Nat Genet"},{"issue":"5","key":"2024071115211573200_bib15","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1158\/1541-7786.MCR-16-0305","article-title":"Comprehensive transcriptome and mutational profiling of endemic Burkitt lymphoma reveals EBV type-specific differences","volume":"15","author":"Kaymaz","year":"2017","journal-title":"Mol Cancer Res"},{"issue":"1","key":"2024071115211573200_bib16","doi-asserted-by":"crossref","first-page":"1459","DOI":"10.1038\/s41467-019-08578-3","article-title":"Genomic and transcriptomic changes complement each other in the pathogenesis of sporadic Burkitt lymphoma","volume":"10","author":"L\u00f3pez","year":"2019","journal-title":"Nat Commun"},{"issue":"19","key":"2024071115211573200_bib17","doi-asserted-by":"crossref","first-page":"1598","DOI":"10.1182\/blood.2019001880","article-title":"The whole-genome landscape of Burkitt lymphoma subtypes","volume":"134","author":"Panea","year":"2019","journal-title":"Blood"},{"issue":"3","key":"2024071115211573200_bib18","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.1182\/blood-2005-01-0168","article-title":"Immunoglobulin gene analysis reveals 2 distinct cells of origin for EBV-positive and EBV-negative Burkitt lymphomas","volume":"106","author":"Bellan","year":"2005","journal-title":"Blood"},{"issue":"10","key":"2024071115211573200_bib19","doi-asserted-by":"crossref","first-page":"e1005158","DOI":"10.1371\/journal.ppat.1005158","article-title":"Distinct viral and mutational spectrum of endemic Burkitt lymphoma","volume":"11","author":"Abate","year":"2015","journal-title":"PLoS Pathog"},{"issue":"8","key":"2024071115211573200_bib20","doi-asserted-by":"crossref","first-page":"904","DOI":"10.1182\/blood.2022016534","article-title":"Genetic subgroups inform on pathobiology in adult and pediatric Burkitt lymphoma","volume":"141","author":"Thomas","year":"2023","journal-title":"Blood"},{"issue":"12","key":"2024071115211573200_bib21","doi-asserted-by":"crossref","first-page":"1313","DOI":"10.1182\/blood-2018-09-871418","article-title":"Genome-wide discovery of somatic coding and noncoding mutations in pediatric endemic and sporadic Burkitt lymphoma","volume":"133","author":"Grande","year":"2019","journal-title":"Blood"},{"issue":"11","key":"2024071115211573200_bib22","doi-asserted-by":"crossref","first-page":"1563","DOI":"10.3324\/haematol.2009.008474","article-title":"Strong lymphoid nuclear expression of SOX11 transcription factor defines lymphoblastic neoplasms, mantle cell lymphoma and Burkitt\u2019s lymphoma","volume":"94","author":"Dictor","year":"2009","journal-title":"Haematologica"},{"issue":"11","key":"2024071115211573200_bib23","doi-asserted-by":"crossref","first-page":"1555","DOI":"10.3324\/haematol.2009.010264","article-title":"SOX11 expression is highly specific for mantle cell lymphoma and identifies the cyclin D1-negative subtype","volume":"94","author":"Mozos","year":"2009","journal-title":"Haematologica"},{"issue":"7","key":"2024071115211573200_bib24","doi-asserted-by":"crossref","first-page":"1760","DOI":"10.1080\/10428194.2016.1258701","article-title":"Frequency and clinical implications of SOX11 expression in Burkitt lymphoma","volume":"58","author":"W\u00e4sterlid","year":"2017","journal-title":"Leuk Lymphoma"},{"issue":"16","key":"2024071115211573200_bib25","doi-asserted-by":"crossref","first-page":"3757","DOI":"10.1182\/blood-2011-05-349662","article-title":"Molecular distinctions between pediatric and adult mature B-cell non-Hodgkin lymphomas identified through genomic profiling","volume":"119","author":"Deffenbacher","year":"2012","journal-title":"Blood"},{"issue":"23","key":"2024071115211573200_bib26","doi-asserted-by":"crossref","first-page":"2419","DOI":"10.1056\/NEJMoa055351","article-title":"A\u00a0biologic definition of Burkitt\u2019s lymphoma from transcriptional and genomic profiling","volume":"354","author":"Hummel","year":"2006","journal-title":"N\u00a0Engl J Med"},{"issue":"4","key":"2024071115211573200_bib27","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1097\/MOH.0000000000000434","article-title":"SOX11, a key oncogenic factor in mantle cell lymphoma","volume":"25","author":"Beekman","year":"2018","journal-title":"Curr Opin Hematol"},{"issue":"12","key":"2024071115211573200_bib28","doi-asserted-by":"crossref","first-page":"2175","DOI":"10.1182\/blood-2012-06-438937","article-title":"SOX11 regulates PAX5 expression and blocks terminal B-cell differentiation in aggressive mantle cell lymphoma","volume":"121","author":"Vegliante","year":"2013","journal-title":"Blood"},{"issue":"7","key":"2024071115211573200_bib29","doi-asserted-by":"crossref","first-page":"1596","DOI":"10.1038\/leu.2015.355","article-title":"SOX11 defines two different subtypes of mantle cell lymphoma through transcriptional regulation of BCL6","volume":"30","author":"Palomero","year":"2016","journal-title":"Leukemia"},{"issue":"20","key":"2024071115211573200_bib30","doi-asserted-by":"crossref","first-page":"2247","DOI":"10.1182\/blood-2018-02-832535","article-title":"SOX11 augments BCR signaling to drive MCL-like tumor development","volume":"131","author":"Kuo","year":"2018","journal-title":"Blood"},{"issue":"14","key":"2024071115211573200_bib31","doi-asserted-by":"crossref","first-page":"2235","DOI":"10.1182\/blood-2014-04-569566","article-title":"SOX11 promotes tumor angiogenesis through transcriptional regulation of PDGFA in mantle cell lymphoma","volume":"124","author":"Palomero","year":"2014","journal-title":"Blood"},{"issue":"4","key":"2024071115211573200_bib32","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1182\/blood-2017-04-776740","article-title":"SOX11 promotes tumor protective microenvironment interactions through CXCR4 and FAK regulation in mantle cell lymphoma","volume":"130","author":"Balsas","year":"2017","journal-title":"Blood"},{"issue":"22","key":"2024071115211573200_bib33","doi-asserted-by":"crossref","first-page":"2202","DOI":"10.1182\/blood.2020010527","article-title":"SOX11, CD70, and Treg cells configure the tumor immune microenvironment of aggressive mantle cell lymphoma","volume":"138","author":"Balsas","year":"2021","journal-title":"Blood"},{"issue":"2","key":"2024071115211573200_bib34","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1038\/s41375-022-01776-x","article-title":"Tumorigenic role of Musashi-2 in aggressive mantle cell lymphoma","volume":"37","author":"Sureda-G\u00f3mez","year":"2023","journal-title":"Leukemia"},{"issue":"1","key":"2024071115211573200_bib35","doi-asserted-by":"crossref","first-page":"3881","DOI":"10.1038\/s41467-022-31355-8","article-title":"Clinical relevance of molecular characteristics in Burkitt lymphoma differs according to age","volume":"13","author":"Burkhardt","year":"2022","journal-title":"Nat Commun"},{"issue":"4","key":"2024071115211573200_bib36","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1182\/blood-2017-07-797019","article-title":"Expression of TP53 is associated with the outcome of MCL independent of MIPI and Ki-67 in trials of the European MCL Network","volume":"131","author":"Aukema","year":"2018","journal-title":"Blood"},{"issue":"2","key":"2024071115211573200_bib37","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1007\/s00428-020-02750-7","article-title":"Reproducibility of histologic prognostic parameters for mantle cell lymphoma: cytology, Ki67, p53 and SOX11","volume":"477","author":"Croci","year":"2020","journal-title":"Virchows Arch"},{"issue":"12","key":"2024071115211573200_bib38","doi-asserted-by":"crossref","first-page":"2407","DOI":"10.1038\/s41379-020-0575-3","article-title":"Frequent traces of EBV infection in Hodgkin and non-Hodgkin lymphomas classified as EBV-negative by routine methods: expanding the landscape of EBV-related lymphomas","volume":"33","author":"Mundo","year":"2020","journal-title":"Mod Pathol"},{"issue":"1","key":"2024071115211573200_bib39","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1186\/s13027-022-00469-5","article-title":"EBV persistence in gastric cancer cases conventionally classified as EBER-ISH negative","volume":"17","author":"Siciliano","year":"2022","journal-title":"Infect Agent Cancer"},{"issue":"W1","key":"2024071115211573200_bib40","doi-asserted-by":"crossref","first-page":"W537","DOI":"10.1093\/nar\/gky379","article-title":"The Galaxy platform for accessible, reproducible and collaborative biomedical analyses: 2018 update","volume":"46","author":"Afgan","year":"2018","journal-title":"Nucleic Acids Res"},{"issue":"2","key":"2024071115211573200_bib41","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1016\/j.immuni.2019.07.001","article-title":"Class-switch recombination occurs infrequently in germinal centers","volume":"51","author":"Roco","year":"2019","journal-title":"Immunity"},{"issue":"12","key":"2024071115211573200_bib42","doi-asserted-by":"crossref","first-page":"1419","DOI":"10.1182\/blood.2020005289","article-title":"Genomic and epigenomic insights into the origin, pathogenesis, and clinical behavior of mantle cell lymphoma subtypes","volume":"136","author":"Nadeu","year":"2020","journal-title":"Blood"},{"key":"2024071115211573200_bib43","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1186\/1471-2407-10-611","article-title":"Plexin-B1 silencing inhibits ovarian cancer cell migration and invasion","volume":"10","author":"Ye","year":"2010","journal-title":"BMC Cancer"},{"issue":"3","key":"2024071115211573200_bib44","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1002\/ijc.33249","article-title":"Novel insights into the function of CD24: a driving force in cancer","volume":"148","author":"Altevogt","year":"2021","journal-title":"Int J Cancer"},{"issue":"9","key":"2024071115211573200_bib45","doi-asserted-by":"crossref","first-page":"1052","DOI":"10.1038\/s43018-022-00402-0","article-title":"Mex3a marks drug-tolerant persister colorectal cancer cells that mediate relapse after chemotherapy","volume":"3","author":"\u00c1lvarez-Varela","year":"2022","journal-title":"Nat Cancer"},{"issue":"1","key":"2024071115211573200_bib46","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1083\/jcb.117.1.179","article-title":"Role of integrin alpha 4 beta 7\/alpha 4 beta P in lymphocyte adherence to fibronectin and VCAM-1 and in homotypic cell clustering","volume":"117","author":"Ruegg","year":"1992","journal-title":"J\u00a0Cell Biol"},{"issue":"1","key":"2024071115211573200_bib47","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/0092-8674(93)90305-A","article-title":"Alpha 4 beta 7 integrin mediates lymphocyte binding to the mucosal vascular addressin MAdCAM-1","author":"Berlin","year":"1993","journal-title":"Cell"},{"issue":"1","key":"2024071115211573200_bib48","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1038\/s41572-022-00404-3","article-title":"Burkitt\u00a0lymphoma","volume":"8","author":"L\u00f3pez","year":"2022","journal-title":"Nat Rev Dis Primers"},{"issue":"6","key":"2024071115211573200_bib49","doi-asserted-by":"crossref","first-page":"740","DOI":"10.1016\/j.immuni.2008.05.001","article-title":"The biology of intestinal immunoglobulin A responses","volume":"28","author":"Cerutti","year":"2008","journal-title":"Immunity"}],"container-title":["Blood"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/ashpublications.org\/blood\/article-pdf\/144\/2\/187\/2234109\/blood_bld-2023-023242-main.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/ashpublications.org\/blood\/article-pdf\/144\/2\/187\/2234109\/blood_bld-2023-023242-main.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,11]],"date-time":"2024-07-11T15:49:03Z","timestamp":1720712943000},"score":1,"resource":{"primary":{"URL":"https:\/\/ashpublications.org\/blood\/article\/144\/2\/187\/515748\/SOX11-expression-is-restricted-to-EBV-negative"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7,11]]},"references-count":49,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2024,7,11]]}},"URL":"https:\/\/doi.org\/10.1182\/blood.2023023242","relation":{},"ISSN":["0006-4971","1528-0020"],"issn-type":[{"value":"0006-4971","type":"print"},{"value":"1528-0020","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,7,11]]}}}