{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,13]],"date-time":"2026-11-13T15:15:07Z","timestamp":1794582907038,"version":"4.9.1"},"reference-count":25,"publisher":"American Society of Hematology","issue":"9","content-domain":{"domain":["ashpublications.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,2,26]]},"abstract":"<jats:sec>\n                    <jats:title>Abstract<\/jats:title>\n                    <jats:p>A single, universally used tumor classification system is critical to ensure precision in patient care, clinical trial enrollment, and advancing therapy. Since the publication of the third edition of the World Health Organization (WHO) classification in 2001, the hematology and hematopathology community has benefited from a single, widely accepted classification system. However, in 2022, 2 separate classification systems of hematologic and lymphoid neoplasms emerged, namely the fifth edition of the WHO Classification of Haematolymphoid Tumours and the International Consensus Classification. This has created confusion and has led to a global call to action to return to a single classification system. In 2024, leaders of the Society for Hematopathology (SH) and the European Association for Haematopathology (EA4HP), together with the leadership of the WHO Classification of Tumours, developed a plan to bridge the division and unite around the next edition of the WHO Classification of Haematologic and Lymphoid Tumours (WHO6). This plan entails convening a classification advancement meeting (CAM), organized by the SH and EA4HP, with broad participation by pathologists, clinicians, and geneticists to discuss and debate updates and changes to the existing classifications. Published conclusions of the CAM meeting will be available for independent consideration by the editorial board of WHO6. We are convinced that engagement with the broader community and the leveraging of global expertise to unite around WHO6 will critically benefit patients, medicine, and science.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1182\/blood.2025030689","type":"journal-article","created":{"date-parts":[[2026,1,2]],"date-time":"2026-01-02T17:15:57Z","timestamp":1767374157000},"page":"915-919","update-policy":"https:\/\/doi.org\/10.1182\/blood.2019cm0000","source":"Crossref","is-referenced-by-count":10,"title":["Advancing the classification of hematolymphoid neoplasms together: for patients, medicine, and science"],"prefix":"10.1182","volume":"147","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7753-0697","authenticated-orcid":false,"given":"Robert P.","family":"Hasserjian","sequence":"first","affiliation":[{"name":"1Department of Pathology, Massachusetts General Hospital, Boston, MA"},{"name":"2Department of Pathology, Harvard Medical School, Boston, MA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2621-3584","authenticated-orcid":false,"given":"Joseph D.","family":"Khoury","sequence":"additional","affiliation":[{"name":"3Department of Pathology, Microbiology, and Immunology, University of Nebraska Medical Center, Omaha, NE"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos","family":"Bueso-Ramos","sequence":"additional","affiliation":[{"name":"4Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan","family":"Dirnhofer","sequence":"additional","affiliation":[{"name":"5Institute of Medical Genetics and Pathology, University Hospital Basel, University of Basel, Basel, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dilani","family":"Lokuhetty","sequence":"additional","affiliation":[{"name":"6International Agency for Research on Cancer and World Health Organization, Evidence Synthesis and Classification Branch, Lyon, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maurilio","family":"Ponzoni","sequence":"additional","affiliation":[{"name":"7Hematopathology Diagnostic Area, Pathology Unit, IRCCS San Raffaele Scientific Institute, University Vita-Salute San Raffaele, Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"234","reference":[{"issue":"12","key":"2026022611211577600_bib1","doi-asserted-by":"crossref","first-page":"4384","DOI":"10.1182\/blood-2008-07-077982","article-title":"Classification of lymphoid neoplasms: the microscope as a tool for disease discovery","volume":"112","author":"Jaffe","year":"2008","journal-title":"Blood"},{"issue":"10","key":"2026022611211577600_bib2","doi-asserted-by":"crossref","first-page":"2112","DOI":"10.1002\/1097-0142(19820515)49:10<2112::AID-CNCR2820491024>3.0.CO;2-2","article-title":"National Cancer Institute sponsored study of classifications of non-Hodgkin's lymphomas: summary and description of a working formulation for clinical usage. The Non-Hodgkin's Lymphoma Pathologic Classification Project","volume":"49","year":"1982","journal-title":"Cancer"},{"issue":"1","key":"2026022611211577600_bib3","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1002\/1097-0142(19850101)55:1<91::AID-CNCR2820550115>3.0.CO;2-K","article-title":"Classification of non-Hodgkin's lymphomas. Reproducibility of major classification systems. NCI non-Hodgkin's Classification Project Writing Committee","volume":"55","year":"1985","journal-title":"Cancer"},{"issue":"5","key":"2026022611211577600_bib4","doi-asserted-by":"crossref","first-page":"1361","DOI":"10.1182\/blood.V84.5.1361.1361","article-title":"A revised European-American classification of lymphoid neoplasms: a proposal from the International Lymphoma Study Group","volume":"84","author":"Harris","year":"1994","journal-title":"Blood"},{"key":"2026022611211577600_bib5","volume-title":"World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of Haematopoietic and Lymphoid Tissues","year":"2001","edition":"ed 3rd"},{"key":"2026022611211577600_bib6","volume-title":"WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues","year":"2008","edition":"ed 4th"},{"key":"2026022611211577600_bib7","volume-title":"WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues","year":"2017","edition":"ed Revised 4th"},{"issue":"7","key":"2026022611211577600_bib8","doi-asserted-by":"crossref","first-page":"1703","DOI":"10.1038\/s41375-022-01613-1","article-title":"The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours: myeloid and histiocytic\/dendritic neoplasms","volume":"36","author":"Khoury","year":"2022","journal-title":"Leukemia"},{"issue":"7","key":"2026022611211577600_bib9","doi-asserted-by":"crossref","first-page":"1720","DOI":"10.1038\/s41375-022-01620-2","article-title":"The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours: lymphoid neoplasms","volume":"36","author":"Alaggio","year":"2022","journal-title":"Leukemia"},{"issue":"11","key":"2026022611211577600_bib10","doi-asserted-by":"crossref","first-page":"1229","DOI":"10.1182\/blood.2022015851","article-title":"The International Consensus Classification of Mature Lymphoid Neoplasms: a report from the Clinical Advisory Committee","volume":"140","author":"Campo","year":"2022","journal-title":"Blood"},{"issue":"11","key":"2026022611211577600_bib11","doi-asserted-by":"crossref","first-page":"1200","DOI":"10.1182\/blood.2022015850","article-title":"International Consensus Classification of Myeloid Neoplasms and Acute Leukemias: integrating morphologic, clinical, and genomic data","volume":"140","author":"Arber","year":"2022","journal-title":"Blood"},{"issue":"3","key":"2026022611211577600_bib12","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1002\/ajh.26812","article-title":"Comparison of the International Consensus and 5th WHO edition classifications of adult myelodysplastic syndromes and acute myeloid leukemia","volume":"98","author":"Falini","year":"2023","journal-title":"Am J Hematol"},{"issue":"7","key":"2026022611211577600_bib13","doi-asserted-by":"crossref","first-page":"1413","DOI":"10.1038\/s41375-023-01909-w","article-title":"AML classification in the year 2023: how to avoid a Babylonian confusion of languages","volume":"37","author":"Huber","year":"2023","journal-title":"Leukemia"},{"issue":"9","key":"2026022611211577600_bib14","doi-asserted-by":"crossref","first-page":"e767","DOI":"10.1016\/S2352-3026(23)00159-X","article-title":"Standardising acute myeloid leukaemia classification systems: a perspective from a panel of international experts","volume":"10","author":"Shallis","year":"2023","journal-title":"Lancet Haematol"},{"issue":"12","key":"2026022611211577600_bib15","doi-asserted-by":"crossref","first-page":"2939","DOI":"10.1038\/s41375-022-01724-9","article-title":"Finding consistency in classifications of myeloid neoplasms: a perspective on behalf of the International Workshop for Myelodysplastic Syndromes","volume":"36","author":"Zeidan","year":"2022","journal-title":"Leukemia"},{"issue":"8","key":"2026022611211577600_bib16","doi-asserted-by":"crossref","first-page":"1523","DOI":"10.1200\/JCO.22.02680","article-title":"What is in a name? Consequences of the classification schism in hematopathology","volume":"41","author":"Aster","year":"2023","journal-title":"J Clin Oncol"},{"issue":"1","key":"2026022611211577600_bib17","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1186\/s13045-024-01571-4","article-title":"A practical approach on the classifications of myeloid neoplasms and acute leukemia: WHO and ICC","volume":"17","author":"Xiao","year":"2024","journal-title":"J Hematol Oncol"},{"issue":"12","key":"2026022611211577600_bib18","doi-asserted-by":"crossref","first-page":"2709","DOI":"10.1182\/bloodadvances.2022008747","article-title":"An agenda to advance research in myelodysplastic syndromes: a TOP 10 priority list from the first international workshop in MDS","volume":"7","author":"Stahl","year":"2023","journal-title":"Blood Adv"},{"issue":"12","key":"2026022611211577600_bib19","doi-asserted-by":"crossref","first-page":"2934","DOI":"10.1038\/s41375-022-01754-3","article-title":"Differences in classification schemata for myelodysplastic\/myeloproliferative overlap neoplasms","volume":"36","author":"Patnaik","year":"2022","journal-title":"Leukemia"},{"issue":"7","key":"2026022611211577600_bib20","doi-asserted-by":"crossref","first-page":"1701","DOI":"10.1038\/s41375-022-01625-x","article-title":"The WHO classification of haematolymphoid tumours","volume":"36","author":"Cree","year":"2022","journal-title":"Leukemia"},{"issue":"11","key":"2026022611211577600_bib21","doi-asserted-by":"crossref","first-page":"e862","DOI":"10.1016\/S2352-3026(24)00251-5","article-title":"Data-driven, harmonised classification system for myelodysplastic syndromes: a consensus paper from the International Consortium for Myelodysplastic Syndromes","volume":"11","author":"Komrokji","year":"2024","journal-title":"Lancet Haematol"},{"issue":"27","key":"2026022611211577600_bib22","doi-asserted-by":"crossref","first-page":"3177","DOI":"10.1200\/JCO.24.00070","article-title":"Lymphoma classifications, how to develop a future unified taxonomy","volume":"42","author":"Campo","year":"2024","journal-title":"J Clin Oncol"},{"issue":"6","key":"2026022611211577600_bib23","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1111\/his.15325","article-title":"WHO classification of tumours: moving towards the sixth edition","volume":"86","author":"Giesen","year":"2025","journal-title":"Histopathology"},{"issue":"12","key":"2026022611211577600_bib24","doi-asserted-by":"crossref","first-page":"3835","DOI":"10.1200\/JCO.1999.17.12.3835","article-title":"World Health Organization classification of neoplastic diseases of the hematopoietic and lymphoid tissues: report of the Clinical Advisory Committee meeting-Airlie House, Virginia, November 1997","volume":"17","author":"Harris","year":"1999","journal-title":"J Clin Oncol"},{"issue":"suppl 1","key":"2026022611211577600_bib25","first-page":"S8","article-title":"World Health Organization classification of neoplastic diseases of the hematopoietic and lymphoid tissues. A progress report","volume":"111","author":"Jaffe","year":"1999","journal-title":"Am J Clin Pathol"}],"container-title":["Blood"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/ashpublications.org\/blood\/article-pdf\/doi\/10.1182\/blood.2025030689\/2504462\/blood_bld-2025-030689-c-main.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/ashpublications.org\/blood\/article-pdf\/doi\/10.1182\/blood.2025030689\/2504462\/blood_bld-2025-030689-c-main.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T16:21:24Z","timestamp":1772122884000},"score":1,"resource":{"primary":{"URL":"https:\/\/ashpublications.org\/blood\/article\/147\/9\/915\/557589\/Advancing-the-classification-of-hematolymphoid"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,26]]},"references-count":25,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2026,2,26]]}},"URL":"https:\/\/doi.org\/10.1182\/blood.2025030689","relation":{},"ISSN":["0006-4971","1528-0020"],"issn-type":[{"value":"0006-4971","type":"print"},{"value":"1528-0020","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026,2,26]]},"published":{"date-parts":[[2026,2,26]]}}}