{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T12:11:38Z","timestamp":1789042298518,"version":"build-2803163510"},"reference-count":10,"publisher":"American Society of Hematology","issue":"11","content-domain":{"domain":["ashpublications.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,9,10]]},"DOI":"10.1182\/blood.2026034640","type":"journal-article","created":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T11:32:08Z","timestamp":1789039928000},"page":"1372-1373","update-policy":"https:\/\/doi.org\/10.1182\/blood.2019cm0000","source":"Crossref","is-referenced-by-count":0,"title":["When membranes fail: FAP-1 and the mega roots of MF"],"prefix":"10.1182","volume":"148","author":[{"given":"Siobhan","family":"Branfield","sequence":"first","affiliation":[{"name":"Boston Children's Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6547-9663","authenticated-orcid":false,"given":"Joseph","family":"Italiano","sequence":"additional","affiliation":[{"name":"Boston Children's Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"234","reference":[{"issue":"11","key":"2026091007320121100_bib1","doi-asserted-by":"crossref","first-page":"1440","DOI":"10.1182\/blood.2025031490","article-title":"FAP-1 loss impairs megakaryocyte demarcation membrane system and platelet function with myelofibrosis-like features","volume":"148","author":"Chiu","year":"2026","journal-title":"Blood"},{"issue":"22","key":"2026091007320121100_bib2","doi-asserted-by":"crossref","first-page":"2168","DOI":"10.1056\/NEJMra1406186","article-title":"Myeloproliferative neoplasms","volume":"376","author":"Spivak","year":"2017","journal-title":"N Engl J Med"},{"issue":"6","key":"2026091007320121100_bib3","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1182\/blood-2016-10-695940","article-title":"Genetic basis and molecular pathophysiology of classical myeloproliferative neoplasms","volume":"129","author":"Vainchenker","year":"2017","journal-title":"Blood"},{"issue":"10","key":"2026091007320121100_bib4","doi-asserted-by":"crossref","first-page":"1767","DOI":"10.1182\/blood-2010-03-274340","article-title":"ADF\/n-cofilin-dependent actin turnover determines platelet formation and sizing","volume":"116","author":"Bender","year":"2010","journal-title":"Blood"},{"issue":"6","key":"2026091007320121100_bib5","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1182\/blood-2013-03-492330","article-title":"Biogenesis of the demarcation membrane system (DMS) in megakaryocytes","volume":"123","author":"Eckly","year":"2014","journal-title":"Blood"},{"issue":"6","key":"2026091007320121100_bib6","doi-asserted-by":"crossref","first-page":"1268","DOI":"10.1111\/jth.13318","article-title":"Cdc42-dependent F-actin dynamics drive structuration of the demarcation membrane system in megakaryocytes","volume":"14","author":"Antkowiak","year":"2016","journal-title":"J Thromb Haemost"},{"issue":"23","key":"2026091007320121100_bib7","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1182\/blood.V126.23.419.419","article-title":"Dynamin 2 (DNM2) and PACSIN2 regulate megakaryocyte demarcation membrane system formation and platelet production in concert","volume":"126","author":"Giannini","year":"2015","journal-title":"Blood"},{"key":"2026091007320121100_bib8","first-page":"5","article-title":"Bone marrow fibrosis in primary myelofibrosis: pathogenic mechanisms and the role of TGF-\u03b2","volume":"3","author":"Agarwal","year":"2016","journal-title":"Stem Cell Investig"},{"issue":"6","key":"2026091007320121100_bib9","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1016\/j.ctrv.2010.02.015","article-title":"Dasatinib: a potent SRC inhibitor in clinical development for the treatment of solid tumors","volume":"36","author":"Araujo","year":"2010","journal-title":"Cancer Treat Rev"},{"issue":"6","key":"2026091007320121100_bib10","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1038\/sj.leu.2404193","article-title":"Epigenetic disruption of two proapoptotic genes MAPK10\/JNK3 and PTPN13\/FAP-1 in multiple lymphomas and carcinomas through hypermethylation of a common bidirectional promoter","volume":"20","author":"Ying","year":"2006","journal-title":"Leukemia"}],"container-title":["Blood"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/ashpublications.org\/blood\/article-pdf\/148\/11\/1372\/2588051\/blood_bld-2026-034640-c-main.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/ashpublications.org\/blood\/article-pdf\/148\/11\/1372\/2588051\/blood_bld-2026-034640-c-main.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T11:32:09Z","timestamp":1789039929000},"score":1,"resource":{"primary":{"URL":"https:\/\/ashpublications.org\/blood\/article\/148\/11\/1372\/570694\/When-membranes-fail-FAP-1-and-the-mega-roots-of-MF"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,10]]},"references-count":10,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2026,9,10]]}},"URL":"https:\/\/doi.org\/10.1182\/blood.2026034640","relation":{},"ISSN":["0006-4971","1528-0020"],"issn-type":[{"value":"0006-4971","type":"print"},{"value":"1528-0020","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026,9,10]]},"published":{"date-parts":[[2026,9,10]]}}}