{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T12:15:24Z","timestamp":1780920924820,"version":"3.54.1"},"reference-count":24,"publisher":"American Society of Hematology","issue":"20","content-domain":{"domain":["ashpublications.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,10,25]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>We conducted one of the first prospective studies to test the hypothesis that the clinical history of priapism underestimates priapism incidence compared with a priapism pain diary. Eligibility criteria were men with sickle cell anemia (SCA) between 18 and 40 years of age who have had at least 3 episodes of priapism in the past 12 months. Seventy-one men with SCA completed the diary for at least 3 months. The first 3 months of the priapism diary were included in the analysis. A total of 298 priapism episodes were recorded, and 80% (57 of 71) of the participants had at least 1 priapism event. Priapism severity was reported in the range of moderate to the worst imaginable pain in 81.5% (263 of 298), and a total 57 participants (80%) had a median pain rating of 6 (interquartile range: 5-8) on a scale from 1 to 10. The monthly incidence rate of priapism per participant based on history versus self-report pain diary was 2.0 (95% confidence interval, 1.9-2.1) and 1.4 (95% confidence interval, 1.2-1.6), respectively (P\u00a0&amp;lt; .001). For participants that had a prior priapism episode, 80% had another episode during the 3-month interval follow-up. The median time to that second episode was 27.5 days. Major priapism occurred in 9.9% of episodes and was associated with the sum of all prospective priapism events. Men with SCA and at least 3 priapism episodes in the past 12 months are at significant risk for recurrent priapism in the following 3 months.<\/jats:p>","DOI":"10.1182\/bloodadvances.2022007285","type":"journal-article","created":{"date-parts":[[2022,7,11]],"date-time":"2022-07-11T19:26:27Z","timestamp":1657567587000},"page":"5676-5683","update-policy":"https:\/\/doi.org\/10.1182\/blood.2019cm0000","source":"Crossref","is-referenced-by-count":14,"title":["Incidence and predictors of priapism events in sickle cell anemia: a\u00a0diary-based analysis"],"prefix":"10.1182","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8363-3094","authenticated-orcid":false,"given":"Ibrahim M.","family":"Idris","sequence":"first","affiliation":[{"name":"1Department of Haematology, Aminu Kano Teaching Hospital\/Bayero University, Kano, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akib","family":"Abba","sequence":"additional","affiliation":[{"name":"1Department of Haematology, Aminu Kano Teaching Hospital\/Bayero University, Kano, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jamil A.","family":"Galadanci","sequence":"additional","affiliation":[{"name":"2Department of Computer Science, Bayero University, Kano, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sani A.","family":"Aji","sequence":"additional","affiliation":[{"name":"3Department of Surgery, Aminu Kano Teaching Hospital, Kano, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atiku U.","family":"Jibrilla","sequence":"additional","affiliation":[{"name":"3Department of Surgery, Aminu Kano Teaching Hospital, Kano, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7258-0073","authenticated-orcid":false,"given":"Mark","family":"Rodeghier","sequence":"additional","affiliation":[{"name":"4Mark Consulting, Chicago, IL"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adetola","family":"Kassim","sequence":"additional","affiliation":[{"name":"5Department of Medicine, Vanderbilt University Medical Center, Nashville, TN"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arthur L.","family":"Burnett","sequence":"additional","affiliation":[{"name":"6School of Medicine, Johns Hopkins University, Baltimore, MD"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0574-1604","authenticated-orcid":false,"given":"Michael R.","family":"DeBaun","sequence":"additional","affiliation":[{"name":"7Vanderbilt-Meharry Sickle Cell Disease Center of Excellence, Vanderbilt University Medical Center, Nashville, 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