{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T03:35:29Z","timestamp":1769571329829,"version":"3.49.0"},"reference-count":66,"publisher":"American Society of Hematology","issue":"2","content-domain":{"domain":["ashpublications.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,1,27]]},"abstract":"<jats:sec>\n                    <jats:title>Abstract<\/jats:title>\n                    <jats:p>Although obesity is an established modifiable risk factor for multiple myeloma (MM), the influence of obesity on survival among Black patients, among whom obesity and MM are more common, is less clear. We evaluated the association of body mass index (BMI) with progression free survival and overall survival among 834 histologically confirmed patients with newly diagnosed MM (NDMM) enrolled in the Integrative Molecular And Genetic Epidemiology study between 2009 and 2020. We estimated the association of BMI with the risk for progressed disease and all-cause and MM-specific mortality using hazard ratios (HR) and corresponding 95% confidence intervals (CI), calculated from multivariable Cox proportional hazard models adjusted for prognostic factors. When compared with NDMM patients with a normal BMI at diagnosis (18.5-24.9 kg\/m2) positive associations with all-cause mortality were observed at the extremes with a 52% and 147% increased risk for death in patients with underweight (BMI, &amp;lt;18.5 kg\/m2, HR, 1.52; 95% CI 0.48-4.84) and those with obesity (BMI, \u226530.0 kg\/m2, HR, 2.47; 95% CI, 1.26-4.85), respectively. Patients with severe obesity (BMI, \u226535kg\/m2) had the highest risk when compared with those with a normal BMI (HR, 3.14; 95% CI, 1.50-6.55), particularly among White (HR, 3.22; 95% CI, 1.30-7.94) and female (HR, 4.17; 95% CI, 1.20-14.47) patients with NDMM; however, the differences by race and sex were not statistically significant (Pinteraction \u2265.60). Severe obesity was also associated with an 83% elevated risk for progressed disease among patients with NDMM (HR, 1.83; 95% CI, 1.04-3.24). These findings were similar for MM-specific mortality and highlight weight management as a potential strategy to improve the prognosis of all patients with NDMM.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1182\/bloodadvances.2025018024","type":"journal-article","created":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T18:02:59Z","timestamp":1761674579000},"page":"439-451","update-policy":"https:\/\/doi.org\/10.1182\/blood.2019cm0000","source":"Crossref","is-referenced-by-count":0,"title":["Impact of body mass index on the prognosis of patients with newly diagnosed multiple myeloma"],"prefix":"10.1182","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-1730-9700","authenticated-orcid":false,"given":"Kevin D.","family":"Arnold","sequence":"first","affiliation":[{"name":"1Department of Pathology, Heersink School of Medicine, The University of Alabama at Birmingham, Birmingham, AL"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0207-4006","authenticated-orcid":false,"given":"Krystle L.","family":"Ong","sequence":"additional","affiliation":[{"name":"1Department of Pathology, Heersink School of Medicine, The University of Alabama at Birmingham, Birmingham, AL"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0467-1819","authenticated-orcid":false,"given":"Gayathri","family":"Ravi","sequence":"additional","affiliation":[{"name":"2Division of Hematology and Medical Oncology, Department of Medicine, Heersink School of Medicine, The University of Alabama at Birmingham, Birmingham, AL"},{"name":"3O\u2019Neal Comprehensive Cancer Center, The University of Alabama at Birmingham, Birmingham, AL"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meredith C.","family":"Wessel","sequence":"additional","affiliation":[{"name":"1Department of Pathology, Heersink School of Medicine, The University of Alabama at Birmingham, Birmingham, AL"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Faith E.","family":"Davies","sequence":"additional","affiliation":[{"name":"4Perlmutter Comprehensive Cancer Center, New York University Langone Health, New York, NY"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5362-2469","authenticated-orcid":false,"given":"Luciano J.","family":"Costa","sequence":"additional","affiliation":[{"name":"2Division of Hematology and Medical Oncology, Department of Medicine, Heersink School of Medicine, The University of Alabama at Birmingham, Birmingham, AL"},{"name":"3O\u2019Neal Comprehensive Cancer Center, The University of Alabama at Birmingham, Birmingham, AL"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ananya","family":"Deshpande","sequence":"additional","affiliation":[{"name":"1Department of Pathology, Heersink School of Medicine, The University of Alabama at Birmingham, Birmingham, AL"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gareth J.","family":"Morgan","sequence":"additional","affiliation":[{"name":"4Perlmutter Comprehensive Cancer Center, New York University Langone Health, New York, NY"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brenda M.","family":"Birmann","sequence":"additional","affiliation":[{"name":"5Channing Division of Network Medicine, Department of Medicine, Brigham and Women\u2019s Hospital and Harvard Medical School, Boston, MA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4498-7858","authenticated-orcid":false,"given":"Elizabeth E.","family":"Brown","sequence":"additional","affiliation":[{"name":"1Department of Pathology, Heersink School of Medicine, The University of Alabama at Birmingham, Birmingham, AL"},{"name":"3O\u2019Neal Comprehensive Cancer Center, The University of Alabama at Birmingham, Birmingham, AL"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"234","published-online":{"date-parts":[[2026,1,16]]},"reference":[{"issue":"1","key":"2026012710065918800_bib1","first-page":"10","article-title":"Cancer statistics, 2025","volume":"75","author":"Siegel","year":"2025","journal-title":"CA Cancer J Clin"},{"key":"2026012710065918800_bib2","unstructured":"American Cancer Center\n          . Survival Rates for Multiple Myeloma. Accessed 3 November 2025. https:\/\/www.cancer.org\/cancer\/types\/multiple-myeloma\/detection-diagnosis-staging\/survival-rates.html."},{"issue":"5","key":"2026012710065918800_bib3","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1002\/ajh.25791","article-title":"Multiple myeloma: 2020 update on diagnosis, risk-stratification and management","volume":"95","author":"Rajkumar","year":"2020","journal-title":"Am J Hematol"},{"issue":"2","key":"2026012710065918800_bib4","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1038\/s41416-024-02723-6","article-title":"Anthropometric traits and risk of multiple myeloma: differences by race, sex and diagnostic clinical features","volume":"131","author":"Arnold","year":"2024","journal-title":"Br J Cancer"},{"issue":"7","key":"2026012710065918800_bib5","doi-asserted-by":"crossref","first-page":"1296","DOI":"10.1038\/s41416-022-01907-2","article-title":"Anthropometric traits and risk of multiple myeloma: a pooled prospective analysis","volume":"127","author":"Bertrand","year":"2022","journal-title":"Br J Cancer"},{"issue":"6","key":"2026012710065918800_bib6","doi-asserted-by":"crossref","first-page":"876","DOI":"10.1158\/1055-9965.EPI-16-0762-T","article-title":"Young adult and usual adult body mass index and multiple myeloma risk: a pooled analysis in the International Multiple Myeloma Consortium (IMMC)","volume":"26","author":"Birmann","year":"2017","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"issue":"8","key":"2026012710065918800_bib7","doi-asserted-by":"crossref","first-page":"794","DOI":"10.1056\/NEJMsr1606602","article-title":"Body fatness and cancer--viewpoint of the IARC Working Group","volume":"375","author":"Lauby-Secretan","year":"2016","journal-title":"N Engl J Med"},{"issue":"11","key":"2026012710065918800_bib8","doi-asserted-by":"crossref","first-page":"1606","DOI":"10.1016\/j.ejca.2011.01.020","article-title":"Body mass index and risk of multiple myeloma: a meta-analysis of prospective studies","volume":"47","author":"Wallin","year":"2011","journal-title":"Eur J Cancer"},{"key":"2026012710065918800_bib9","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.2025.287724","article-title":"Racial differences in the proportion of myeloma cases attributable to excess body weight and diabetes mellitus in the United States","author":"Anuraj","year":"21  2025","journal-title":"Haematol"},{"key":"2026012710065918800_bib10","unstructured":"National Center for Health Statistics\n          . National Health Interview Survey. Accessed 3 November 2025. https:\/\/www.cdc.gov\/nchs\/nhis\/index.htm."},{"issue":"8","key":"2026012710065918800_bib11","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1056\/NEJMoa055643","article-title":"Overweight, obesity, and mortality in a large prospective cohort of persons 50 to 71 years old","volume":"355","author":"Adams","year":"2006","journal-title":"N Engl J Med"},{"issue":"17","key":"2026012710065918800_bib12","doi-asserted-by":"crossref","first-page":"1625","DOI":"10.1056\/NEJMoa021423","article-title":"Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults","volume":"348","author":"Calle","year":"2003","journal-title":"N Engl J Med"},{"issue":"8","key":"2026012710065918800_bib13","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1016\/0021-9681(79)90119-X","article-title":"Variations in mortality by weight among 750,000 men and women","volume":"32","author":"Lew","year":"1979","journal-title":"J Chronic Dis"},{"issue":"10","key":"2026012710065918800_bib14","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1634\/theoncologist.2010-0206","article-title":"Obesity and the risk for a hematological malignancy: leukemia, lymphoma, or myeloma","volume":"15","author":"Lichtman","year":"2010","journal-title":"Oncologist"},{"issue":"8","key":"2026012710065918800_bib15","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1016\/S1470-2045(10)70141-8","article-title":"Body-mass index and cancer mortality in the Asia-Pacific cohort studies collaboration: pooled analyses of 424,519 participants","volume":"11","author":"Parr","year":"2010","journal-title":"Lancet Oncol"},{"issue":"7630","key":"2026012710065918800_bib16","doi-asserted-by":"crossref","first-page":"1134","DOI":"10.1136\/bmj.39367.495995.AE","article-title":"Cancer incidence and mortality in relation to body mass index in the Million Women Study: cohort study","volume":"335","author":"Reeves","year":"2007","journal-title":"BMJ"},{"issue":"2","key":"2026012710065918800_bib17","doi-asserted-by":"crossref","first-page":"273","DOI":"10.4081\/gh.2012.145","article-title":"A multi-stage approach to maximizing geocoding success in a large population-based cohort study through automated and interactive processes","volume":"6","author":"Sonderman","year":"2012","journal-title":"Geospat Health"},{"issue":"5","key":"2026012710065918800_bib18","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1111\/bjh.12935","article-title":"Body size and multiple myeloma mortality: a pooled analysis of 20 prospective studies","volume":"166","author":"Teras","year":"2014","journal-title":"Br J Haematol"},{"issue":"11","key":"2026012710065918800_bib19","doi-asserted-by":"crossref","first-page":"1861","DOI":"10.1158\/1055-9965.EPI-19-0389","article-title":"Association of BMI, smoking, and alcohol with multiple myeloma mortality in Asians: a pooled analysis of more than 800,000 participants in the Asia Cohort Consortium","volume":"28","author":"Ugai","year":"2019","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"issue":"10","key":"2026012710065918800_bib20","doi-asserted-by":"crossref","first-page":"1074","DOI":"10.1634\/theoncologist.2013-0015","article-title":"Influence of body mass index on survival in veterans with multiple myeloma","volume":"18","author":"Beason","year":"2013","journal-title":"Oncologist"},{"issue":"5","key":"2026012710065918800_bib21","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1007\/s00277-013-1977-9","article-title":"Decreased body mass index is associated with poor prognosis in patients with multiple myeloma","volume":"93","author":"Jung","year":"2014","journal-title":"Ann Hematol"},{"issue":"1","key":"2026012710065918800_bib22","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1038\/s41408-022-00782-7","article-title":"Extreme body mass index and survival in newly diagnosed multiple myeloma patients","volume":"13","author":"Shah","year":"2023","journal-title":"Blood Cancer J"},{"issue":"7","key":"2026012710065918800_bib23","first-page":"3991","article-title":"Underweight as a risk factor of mortality in patients with newly diagnosed multiple myeloma","volume":"29","author":"Tsai","year":"2021","journal-title":"Support Care Cancer"},{"issue":"12","key":"2026012710065918800_bib24","doi-asserted-by":"crossref","first-page":"2348","DOI":"10.1158\/1055-9965.EPI-06-0007","article-title":"Body mass index, abnormal glucose metabolism, and mortality from hematopoietic cancer","volume":"15","author":"Chiu","year":"2006","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"issue":"21","key":"2026012710065918800_bib25","doi-asserted-by":"crossref","first-page":"5331","DOI":"10.3390\/cancers14215331","article-title":"Body mass index and overall survival of patients with newly diagnosed multiple myeloma","volume":"14","author":"Wang","year":"2022","journal-title":"Cancers (Basel)"},{"key":"2026012710065918800_bib26","unstructured":"National Center for Health Statistics\n          . Interactive Data Visualizations. Accessed 1 November 2025. https:\/\/www.cdc.gov\/places\/tools\/interactive-map-tool.html."},{"issue":"12","key":"2026012710065918800_bib27","doi-asserted-by":"crossref","first-page":"e538","DOI":"10.1016\/S1470-2045(14)70442-5","article-title":"International Myeloma Working Group updated criteria for the diagnosis of multiple myeloma","volume":"15","author":"Rajkumar","year":"2014","journal-title":"Lancet Oncol"},{"issue":"8","key":"2026012710065918800_bib28","doi-asserted-by":"crossref","first-page":"e328","DOI":"10.1016\/S1470-2045(16)30206-6","article-title":"International Myeloma Working Group consensus criteria for response and minimal residual disease assessment in multiple myeloma","volume":"17","author":"Kumar","year":"2016","journal-title":"Lancet Oncol"},{"issue":"17","key":"2026012710065918800_bib29","doi-asserted-by":"crossref","first-page":"1855","DOI":"10.1001\/archinte.158.17.1855","article-title":"Executive summary of the clinical guidelines on the identification, evaluation, and treatment of overweight and obesity in adults","volume":"158","author":"Sj\u00f6str\u00f6m","year":"1998","journal-title":"Arch Intern Med"},{"issue":"4","key":"2026012710065918800_bib30","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1093\/ajcn\/68.4.899","article-title":"Clinical guidelines on the identification, evaluation, and treatment of overweight and obesity in adults: executive summary. Expert panel on the identification, evaluation, and treatment of overweight in adults","volume":"68","year":"1998","journal-title":"Am J Clin Nutr"},{"issue":"19","key":"2026012710065918800_bib31","doi-asserted-by":"crossref","first-page":"1737","DOI":"10.1056\/NEJMoa2102953","article-title":"New creatinine- and cystatin C-based equations to estimate GFR without race","volume":"385","author":"Inker","year":"2021","journal-title":"N Engl J Med"},{"issue":"2","key":"2026012710065918800_bib32","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1038\/leu.2011.204","article-title":"A novel prognostic model in myeloma based on co-segregating adverse FISH lesions and the ISS: analysis of patients treated in the MRC Myeloma IX trial","volume":"26","author":"Boyd","year":"2012","journal-title":"Leukemia"},{"issue":"1","key":"2026012710065918800_bib33","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/S1470-2045(18)30687-9","article-title":"Lenalidomide maintenance versus observation for patients with newly diagnosed multiple myeloma (Myeloma XI): a multicentre, open-label, randomised, phase 3 trial","volume":"20","author":"Jackson","year":"2019","journal-title":"Lancet Oncol"},{"issue":"5","key":"2026012710065918800_bib34","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/0021-9681(87)90171-8","article-title":"A new method of classifying prognostic comorbidity in longitudinal studies: development and validation","volume":"40","author":"Charlson","year":"1987","journal-title":"J Chronic Dis"},{"issue":"4","key":"2026012710065918800_bib35","first-page":"575","article-title":"Risk factors for multiple myeloma: evidence from the Japan Collaborative Cohort (JACC) study","volume":"7","author":"Khan","year":"2006","journal-title":"Asian Pac J Cancer Prev"},{"issue":"7630","key":"2026012710065918800_bib36","doi-asserted-by":"crossref","first-page":"1134","DOI":"10.1136\/bmj.39367.495995.AE","article-title":"Cancer incidence and mortality in relation to body mass index in the Million Women Study: cohort study","volume":"335","author":"Reeves","year":"2007","journal-title":"BMJ"},{"issue":"10","key":"2026012710065918800_bib37","doi-asserted-by":"crossref","first-page":"djw120","DOI":"10.1093\/jnci\/djw120","article-title":"Multiple myeloma mortality in relation to obesity among African Americans","volume":"108","author":"Sonderman","year":"2016","journal-title":"J Natl Cancer Inst"},{"issue":"11","key":"2026012710065918800_bib38","doi-asserted-by":"crossref","first-page":"e111980","DOI":"10.1371\/journal.pone.0111980","article-title":"A pooled analysis of body mass index and mortality among African Americans","volume":"9","author":"Cohen","year":"2014","journal-title":"PLoS One"},{"issue":"24","key":"2026012710065918800_bib39","doi-asserted-by":"crossref","first-page":"2615","DOI":"10.1182\/blood.2019000406","article-title":"With equal access, African American patients have superior survival compared to white patients with multiple myeloma: a VA study","volume":"133","author":"Fillmore","year":"2019","journal-title":"Blood"},{"issue":"1","key":"2026012710065918800_bib40","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1002\/cncr.33208","article-title":"African Americans with translocation t(11;14) have superior survival after autologous hematopoietic cell transplantation for multiple myeloma in comparison with Whites in the United States","volume":"127","author":"Badar","year":"2021","journal-title":"Cancer"},{"issue":"9","key":"2026012710065918800_bib41","doi-asserted-by":"crossref","first-page":"1590","DOI":"10.1002\/cncr.30526","article-title":"Racial disparities in treatment use for multiple myeloma","volume":"123","author":"Fiala","year":"2017","journal-title":"Cancer"},{"issue":"20","key":"2026012710065918800_bib42","doi-asserted-by":"crossref","first-page":"3183","DOI":"10.1002\/cncr.30183","article-title":"Impact of marital status, insurance status, income, and race\/ethnicity on the survival of younger patients diagnosed with multiple myeloma in the United States","volume":"122","author":"Costa","year":"2016","journal-title":"Cancer"},{"issue":"5","key":"2026012710065918800_bib43","doi-asserted-by":"crossref","first-page":"djw264","DOI":"10.1093\/jnci\/djw264","article-title":"Obesity and the transformation of monoclonal gammopathy of undetermined significance to multiple myeloma: a population-based cohort study","volume":"109","author":"Chang","year":"2017","journal-title":"J Natl Cancer Inst"},{"issue":"4","key":"2026012710065918800_bib44","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1038\/s41408-022-00642-4","article-title":"Body mass index and risk of progression from monoclonal gammopathy of undetermined significance to multiple myeloma: results from the prostate, lung, colorectal and ovarian cancer screening trial","volume":"12","author":"Chang","year":"2022","journal-title":"Blood Cancer J"},{"issue":"4","key":"2026012710065918800_bib45","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1038\/s41408-022-00659-9","article-title":"Body mass index associated with monoclonal gammopathy of undetermined significance (MGUS) progression in Olmsted County, Minnesota","volume":"12","author":"Kleinstern","year":"2022","journal-title":"Blood Cancer J"},{"issue":"24","key":"2026012710065918800_bib46","doi-asserted-by":"crossref","first-page":"2186","DOI":"10.1182\/bloodadvances.2017007609","article-title":"Obesity and risk of monoclonal gammopathy of undetermined significance and progression to multiple myeloma: a population-based study","volume":"1","author":"Thordardottir","year":"2017","journal-title":"Blood Adv"},{"key":"2026012710065918800_bib47","doi-asserted-by":"crossref","first-page":"17105","DOI":"10.1038\/nrdp.2017.105","article-title":"Cancer-associated cachexia","volume":"4","author":"Baracos","year":"2018","journal-title":"Nat Rev Dis Primers"},{"issue":"9868","key":"2026012710065918800_bib48","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1016\/S0140-6736(12)62167-9","article-title":"Frailty in elderly people","volume":"381","author":"Clegg","year":"2013","journal-title":"Lancet"},{"issue":"5","key":"2026012710065918800_bib49","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1038\/nrc3257","article-title":"The genetic architecture of multiple myeloma","volume":"12","author":"Morgan","year":"2012","journal-title":"Nat Rev Cancer"},{"issue":"suppl 1","key":"2026012710065918800_bib50","doi-asserted-by":"crossref","first-page":"S5","DOI":"10.1016\/S0268-960X(10)70003-5","article-title":"Multiple myeloma: biology of the disease","volume":"24","author":"Mahindra","year":"2010","journal-title":"Blood Rev"},{"issue":"11","key":"2026012710065918800_bib51","doi-asserted-by":"crossref","first-page":"1046","DOI":"10.1056\/NEJMra1011442","article-title":"Multiple myeloma","volume":"364","author":"Palumbo","year":"2011","journal-title":"N Engl J Med"},{"issue":"36","key":"2026012710065918800_bib52","doi-asserted-by":"crossref","first-page":"4673","DOI":"10.1038\/onc.2014.403","article-title":"The tumor microenvironment shapes hallmarks of mature B-cell malignancies","volume":"34","author":"Shain","year":"2015","journal-title":"Oncogene"},{"issue":"5","key":"2026012710065918800_bib53","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1016\/S8756-3282(96)00258-X","article-title":"The function of adipocytes in the bone marrow stroma: an update","volume":"19","author":"Gimble","year":"1996","journal-title":"Bone"},{"issue":"10","key":"2026012710065918800_bib54","doi-asserted-by":"crossref","first-page":"1533","DOI":"10.1016\/j.bbalip.2013.02.010","article-title":"Adipose tissue and adipocytes support tumorigenesis and metastasis","volume":"1831","author":"Nieman","year":"2013","journal-title":"Biochim Biophys Acta"},{"issue":"3","key":"2026012710065918800_bib55","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1038\/s42255-019-0041-z","article-title":"Metabolic messengers: adiponectin","volume":"1","author":"Straub","year":"2019","journal-title":"Nat Metab"},{"issue":"10","key":"2026012710065918800_bib56","doi-asserted-by":"crossref","first-page":"2519","DOI":"10.3390\/ijms20102519","article-title":"Adiponectin, obesity, and cancer: clash of the bigwigs in health and disease","volume":"20","author":"Parida","year":"2019","journal-title":"Int J Mol Sci"},{"issue":"suppl","key":"2026012710065918800_bib57","doi-asserted-by":"crossref","first-page":"S395","DOI":"10.1194\/jlr.R800057-JLR200","article-title":"Adipocyte metabolism and obesity","volume":"50","author":"Attie","year":"2009","journal-title":"J Lipid Res"},{"issue":"3","key":"2026012710065918800_bib58","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1007\/s10555-022-10063-1","article-title":"The effect of obesity on adipose-derived stromal cells and adipose tissue and their impact on cancer","volume":"41","author":"Bunnell","year":"2022","journal-title":"Cancer Metastasis Rev"},{"issue":"7","key":"2026012710065918800_bib59","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.1093\/carcin\/bgp127","article-title":"Cancer-related inflammation, the seventh hallmark of cancer: links to genetic instability","volume":"30","author":"Colotta","year":"2009","journal-title":"Carcinogenesis"},{"issue":"2","key":"2026012710065918800_bib60","doi-asserted-by":"crossref","first-page":"116","DOI":"10.3109\/10409238.2013.875514","article-title":"Interplay between DNA repair and inflammation, and the link to cancer","volume":"49","author":"Kidane","year":"2014","journal-title":"Crit Rev Biochem Mol Biol"},{"issue":"1","key":"2026012710065918800_bib61","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1515\/hmbci-2014-0037","article-title":"Adipose tissue, obesity and adipokines: role in cancer promotion","volume":"21","author":"Booth","year":"2015","journal-title":"Horm Mol Biol Clin Investig"},{"issue":"1","key":"2026012710065918800_bib62","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.canlet.2016.06.010","article-title":"Adipocytes contribute to the growth and progression of multiple myeloma: unraveling obesity related differences in adipocyte signaling","volume":"380","author":"Bullwinkle","year":"2016","journal-title":"Cancer Lett"},{"issue":"17","key":"2026012710065918800_bib63","doi-asserted-by":"crossref","first-page":"4347","DOI":"10.3390\/cancers15174347","article-title":"Unlocking drug resistance in multiple myeloma: adipocytes as modulators of treatment response","volume":"15","author":"Ochiai","year":"2023","journal-title":"Cancers (Basel)"},{"key":"2026012710065918800_bib64","unstructured":"Centers for Disease Control and Prevention\n          . Adult Obesity Prevalence Maps. Accessed 17 September 2025. https:\/\/www.cdc.gov\/obesity\/data-and-statistics\/adult-obesity-prevalence-maps.html."},{"issue":"7","key":"2026012710065918800_bib65","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1038\/s41416-018-0010-4","article-title":"Body mass index throughout adulthood, physical activity, and risk of multiple myeloma: a prospective analysis in three large cohorts","volume":"118","author":"Marinac","year":"2018","journal-title":"Br J Cancer"},{"issue":"8","key":"2026012710065918800_bib66","doi-asserted-by":"crossref","first-page":"1906","DOI":"10.1158\/0008-5472.CAN-17-3287","article-title":"The importance of body composition in explaining the overweight paradox in cancer-counterpoint","volume":"78","author":"Caan","year":"2018","journal-title":"Cancer Res"}],"container-title":["Blood Advances"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/ashpublications.org\/bloodadvances\/article-pdf\/10\/2\/439\/2498281\/blooda_adv-2025-018024-main.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/ashpublications.org\/bloodadvances\/article-pdf\/10\/2\/439\/2498281\/blooda_adv-2025-018024-main.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,27]],"date-time":"2026-01-27T15:24:10Z","timestamp":1769527450000},"score":1,"resource":{"primary":{"URL":"https:\/\/ashpublications.org\/bloodadvances\/article\/10\/2\/439\/547953\/Impact-of-body-mass-index-on-the-prognosis-of"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,16]]},"references-count":66,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,1,27]]}},"URL":"https:\/\/doi.org\/10.1182\/bloodadvances.2025018024","relation":{},"ISSN":["2473-9529","2473-9537"],"issn-type":[{"value":"2473-9529","type":"print"},{"value":"2473-9537","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026,1,27]]},"published":{"date-parts":[[2026,1,16]]}}}