{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T19:05:05Z","timestamp":1793387105150,"version":"4.5.0"},"reference-count":45,"publisher":"European Respiratory Society (ERS)","issue":"3","funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["HL65270"],"award-info":[{"award-number":["HL65270"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Spanish Respiratory Society"}],"content-domain":{"domain":["publications.ersnet.org"],"crossmark-restriction":true},"short-container-title":["Eur Respir J"],"accepted":{"date-parts":[[2015,3,15]]},"published-print":{"date-parts":[[2015,9]]},"abstract":"<jats:p>The first line of treatment of obstructive sleep apnoea syndrome (OSAS) in children consists of adenotonsillectomy (T&amp;A). The aim of the present study was to evaluate treatment outcomes of OSAS among obese children recruited from the community.<\/jats:p><jats:p>A cross-sectional, prospective, multicentre study of Spanish obese children aged 3\u201314\u2005years, with four groups available for follow-up: group 1: non-OSAS with no treatment; group 2: dietary treatment; group 3: surgical treatment; and group 4: continuous positive airway pressure treatment.<\/jats:p><jats:p>117 obese children (60 boys, 57 girls) with a mean age of 11.3\u00b12.9\u2005years completed the initial (T<jats:sub>0<\/jats:sub>) and follow-up (T<jats:sub>1)<\/jats:sub>assessments. Their mean body mass index (BMI) at T<jats:sub>1<\/jats:sub>was 27.6\u00b14.7\u2005kg\u00b7m<jats:sup>\u22122<\/jats:sup>, corresponding to a BMI Z-score of 1.34\u00b10.59. Mean respiratory disturbance index (RDI) at follow-up was 3.3\u00b13.9\u2005events\u00b7h<jats:sup>\u22121<\/jats:sup>. Among group 1 children, 21.2% had an RDI \u22653\u2005events\u00b7h<jats:sup>\u22121<\/jats:sup>at T<jats:sub>1<\/jats:sub>, the latter being present in 50% of group 2, and 43.5% in group 3. In the binary logistic regression model, age emerged as a significant risk factor for residual OSAS (odds ratio 1.49, 95% confidence interval 1.01\u20132.23; p&lt;0.05) in obese children surgically treated, and RDI at T<jats:sub>0<\/jats:sub>as well as an increase in BMI emerged as significant risk factors for persistent OSAS in obese children with dietary treatment (OR 1.82, 95% CI 1.09\u20133.02 (p&lt;0.03) and OR 8.71, 95% CI 1.24\u201361.17 (p=0.03)).<\/jats:p><jats:p>Age, RDI at diagnosis and obesity are risk factors for relatively unfavourable OSAS treatment outcomes at follow-up.<\/jats:p>","DOI":"10.1183\/09031936.00013815","type":"journal-article","created":{"date-parts":[[2015,6,12]],"date-time":"2015-06-12T03:06:55Z","timestamp":1434078415000},"page":"717-727","update-policy":"https:\/\/doi.org\/10.1183\/ers-crossmark-policy","source":"Crossref","is-referenced-by-count":42,"title":["Treatment outcomes of obstructive sleep apnoea in obese community-dwelling children: the NANOS study"],"prefix":"10.1183","volume":"46","author":[{"given":"Mar\u00eda Luz","family":"Alonso-\u00c1lvarez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joaquin","family":"Ter\u00e1n-Santos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana Isabel","family":"Navazo-Eg\u00fcia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u00f3nica Gonzalez","family":"Martinez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda Jos\u00e9","family":"Jurado-Luque","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaime","family":"Corral-Pe\u00f1afiel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joaquin","family":"Duran-Cantolla","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Aurelio","family":"Cordero-Guevara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leila","family":"Kheirandish-Gozal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Gozal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"81","published-online":{"date-parts":[[2015,6,11]]},"reference":[{"key":"2024102023332405000_46.3.717.1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200711-1670OC"},{"key":"2024102023332405000_46.3.717.2","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.21370"},{"key":"2024102023332405000_46.3.717.3","doi-asserted-by":"publisher","DOI":"10.1378\/chest.11-1777"},{"key":"2024102023332405000_46.3.717.4","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201104-0721OC"},{"key":"2024102023332405000_46.3.717.5","doi-asserted-by":"crossref","first-page":"605280","DOI":"10.1155\/2014\/605280","article-title":"Inflammatory markers and obstructive sleep apnea in obese children: the NANOS study","volume":"2014","author":"Gileles-Hillel","year":"2014","journal-title":"Mediators Inflamm"},{"key":"2024102023332405000_46.3.717.6","doi-asserted-by":"publisher","DOI":"10.1136\/adc.2006.101089"},{"key":"2024102023332405000_46.3.717.7","doi-asserted-by":"crossref","first-page":"1178","DOI":"10.1038\/oby.2008.673","article-title":"The effect of weight loss on sleep-disordered breathing in obese teenagers","volume":"17","author":"Verhulst","year":"2009","journal-title":"Obesity (Silver Spring)"},{"key":"2024102023332405000_46.3.717.8","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2014.03.024"},{"key":"2024102023332405000_46.3.717.9","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00689.2009"},{"key":"2024102023332405000_46.3.717.10","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201008-1249OC"},{"key":"2024102023332405000_46.3.717.11","doi-asserted-by":"crossref","first-page":"841","DOI":"10.5665\/sleep.2708","article-title":"Adenotonsillectomy in obese children with obstructive sleep apnea syndrome: magnetic resonance imaging findings and considerations","volume":"36","author":"Nandalike","year":"2013","journal-title":"Sleep"},{"key":"2024102023332405000_46.3.717.12","doi-asserted-by":"crossref","first-page":"943","DOI":"10.5665\/sleep.3666","article-title":"Obstructive sleep apnea in obese community-dwelling children: the NANOS study","volume":"37","author":"Alonso-\u00c1lvarez","year":"2014","journal-title":"Sleep"},{"key":"2024102023332405000_46.3.717.13","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2012-1672"},{"key":"2024102023332405000_46.3.717.14","unstructured":"Luz Alonso-\u00c1lvarez M , Canet T , Cubell-Alarco M , et al. 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