{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T18:32:40Z","timestamp":1792089160553,"version":"4.4.0"},"reference-count":35,"publisher":"European Respiratory Society (ERS)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur Respir J"],"accepted":{"date-parts":[[2009,11,4]]},"published-print":{"date-parts":[[2010,4]]},"abstract":"<jats:p>Controls for indoor air quality (IAQ) in schools are not usually performed throughout Europe. The aim of this study was to assess the effects of IAQ on respiratory health of schoolchildren living in Norway, Sweden, Denmark, France and Italy.<\/jats:p><jats:p>In the cross-sectional European Union-funded HESE (Health Effects of School Environment) Study, particulate matter with a 50% cut-off aerodynamic diameter of 10\u2005\u00b5m (PM<jats:sub>10<\/jats:sub>) and CO<jats:sub>2<\/jats:sub>levels in a day of normal activity (full classroom) were related to wheezing, dry cough at night and rhinitis in 654 children (10\u2005yrs) and to acoustic rhinometry in 193 children.<\/jats:p><jats:p>Schoolchildren exposed to PM<jats:sub>10<\/jats:sub>&gt;50\u2005\u03bcg\u00b7m<jats:sup>\u22123<\/jats:sup>and CO<jats:sub>2<\/jats:sub>&gt;1,000\u2005ppm (standards for good IAQ) were 78% and 66%, respectively. All disorders were more prevalent in children from poorly ventilated classrooms. Schoolchildren exposed to CO<jats:sub>2<\/jats:sub>levels &gt;1,000\u2005ppm showed a significantly higher risk for dry cough (OR 2.99, 95% CI 1.65\u20135.44) and rhinitis (OR 2.07, 95% CI 1.14\u20133.73). By two-level (child, classroom) hierarchical analyses, CO<jats:sub>2<\/jats:sub>was significantly associated with dry cough (OR 1.06, 95% CI 1.00\u20131.13 per 100\u2005ppm increment) and rhinitis (OR 1.06, 95% CI 1.00\u20131.11). Nasal patency was significantly lower in schoolchildren exposed to PM<jats:sub>10<\/jats:sub>&gt;50\u2005\u03bcg\u00b7m<jats:sup>\u22123<\/jats:sup>than in those exposed to lower levels.<\/jats:p><jats:p>A poor IAQ is frequent in European classrooms; it is related to respiratory disturbances and affects nasal patency.<\/jats:p>","DOI":"10.1183\/09031936.00016309","type":"journal-article","created":{"date-parts":[[2010,1,15]],"date-time":"2010-01-15T01:33:26Z","timestamp":1263519206000},"page":"742-749","source":"Crossref","is-referenced-by-count":192,"title":["School air quality related to dry cough, rhinitis and nasal patency in children"],"prefix":"10.1183","volume":"35","author":[{"given":"M.","family":"Simoni","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I.","family":"Annesi-Maesano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Sigsgaard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Norback","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Wieslander","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W.","family":"Nystad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Canciani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Sestini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Viegi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"81","published-online":{"date-parts":[[2010,1,14]]},"reference":[{"key":"2024102020102749000_35.4.742.1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jea.7500092"},{"key":"2024102020102749000_35.4.742.2","doi-asserted-by":"crossref","first-page":"1489","DOI":"10.2105\/AJPH.93.9.1489","volume":"93","year":"2003","journal-title":"AJPH"},{"key":"2024102020102749000_35.4.742.3","first-page":"214","volume":"4","year":"1999","journal-title":"Eur Respir Mon"},{"key":"2024102020102749000_35.4.742.4","first-page":"384","volume":"5","year":"2000","journal-title":"Eur Respir Mon"},{"key":"2024102020102749000_35.4.742.5","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jea.7500368"},{"key":"2024102020102749000_35.4.742.6","doi-asserted-by":"crossref","first-page":"1088","DOI":"10.1093\/oxfordjournals.aje.a116952","volume":"139","year":"1994","journal-title":"Am J Epidemiol"},{"key":"2024102020102749000_35.4.742.7","first-page":"1401","volume":"8","year":"2004","journal-title":"Int J Tuberc Lung Dis"},{"key":"2024102020102749000_35.4.742.8","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1289\/ehp.7881","volume":"114","year":"2006","journal-title":"Environ Health Perspect"},{"key":"2024102020102749000_35.4.742.9","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0668.2004.00263.x"},{"key":"2024102020102749000_35.4.742.10","doi-asserted-by":"publisher","DOI":"10.1088\/0952-4746\/26\/1\/005"},{"key":"2024102020102749000_35.4.742.11","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0668.2005.00381.x"},{"key":"2024102020102749000_35.4.742.12","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0668.2001.110207.x"},{"key":"2024102020102749000_35.4.742.13","doi-asserted-by":"publisher","DOI":"10.1034\/j.1398-9995.2000.00353.x"},{"key":"2024102020102749000_35.4.742.14","unstructured":"Carrer P, Bruinen de Bruin Y, Franchi M, et al. 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