{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T00:50:17Z","timestamp":1790038217667,"version":"4.0.1"},"reference-count":23,"publisher":"European Respiratory Society (ERS)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur Respir J"],"accepted":{"date-parts":[[2006,9,20]]},"published-print":{"date-parts":[[2007,2]]},"abstract":"<jats:p>The production of indium-tin oxide has increased, owing to the increased manufacture of liquid-crystal panels. It has been reported that interstitial pneumonia occurred in two indium-processing workers; therefore, the present study aimed to evaluate whether interstitial pulmonary disorders were prevalent among indium workers.<\/jats:p><jats:p>The study was carried out in 108 male workers in the indium plant where the two interstitial pneumonia patients mentioned above were employed, and included high-resolution computed tomography (HRCT) of the lungs, pulmonary function tests and analysis of serum sialylated carbohydrate antigen KL-6 and the serum indium concentration.<\/jats:p><jats:p>Significant interstitial changes were observed in 23 indium workers on HRCT and serum KL-6 was abnormally high (&gt;500 U\u00b7mL<jats:sup>-1<\/jats:sup>) in 40 workers. Workers with serum indium concentrations in the highest quartile had significantly longer exposure periods, greater HRCT changes, lower diffusing capacity of the lung for carbon monoxide and higher KL-6 levels compared with those in the lowest quartile. The serum indium concentration was positively correlated with the KL-6 level and with the degree of HRCT changes.<\/jats:p><jats:p>In conclusion, the results of the present study indicated that serum KL-6 and high-resolution computed tomography abnormalities were prevalent among indium workers and that these abnormalities increased with the indium burden, suggesting that inhaled indium could be a potential cause of occupational lung disease.<\/jats:p>","DOI":"10.1183\/09031936.00020306","type":"journal-article","created":{"date-parts":[[2006,10,19]],"date-time":"2006-10-19T00:13:38Z","timestamp":1161216818000},"page":"317-324","source":"Crossref","is-referenced-by-count":110,"title":["Interstitial pulmonary disorders in indium-processing workers"],"prefix":"10.1183","volume":"29","author":[{"given":"T.","family":"Chonan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"O.","family":"Taguchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Omae","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"81","published-online":{"date-parts":[[2006,10,18]]},"reference":[{"key":"2024102019094908000_29.2.317.1","doi-asserted-by":"publisher","DOI":"10.1006\/faat.1994.1027"},{"key":"2024102019094908000_29.2.317.2","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1006\/enrs.1994.1065","volume":"67","year":"1994","journal-title":"Environ Res"},{"key":"2024102019094908000_29.2.317.3","doi-asserted-by":"publisher","DOI":"10.1539\/joh.44.99"},{"key":"2024102019094908000_29.2.317.4","unstructured":"National Toxicology Program. 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