{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T09:48:51Z","timestamp":1761126531937,"version":"3.37.3"},"reference-count":23,"publisher":"European Respiratory Society (ERS)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur Respir J"],"accepted":{"date-parts":[[2007,4,17]]},"published-print":{"date-parts":[[2007,9]]},"abstract":"<jats:p>Allergic occupational asthma is frequent in farming populations. As educational interventions can improve disease management, the short-term effect of an educational intervention in asthmatic farmers was evaluated on the basis of spirometric indices and exhaled nitric oxide fraction (<jats:italic>F<\/jats:italic><jats:sub>eNO<\/jats:sub>).<\/jats:p><jats:p>Farmers with occupational asthma (n\u200a=\u200a81), mostly sensitised against cow dander and storage mites, participated in a 1-day educational programme. Outcome measures were assessed at baseline and after 4\u20136\u2005weeks, using<jats:italic>F<\/jats:italic><jats:sub>eNO<\/jats:sub>, lung function and a questionnaire. Results were compared with those of a control group without intervention (n\u200a=\u200a24).<\/jats:p><jats:p>In the educational group, the proportion of subjects reporting work-related symptoms was reduced after the intervention. The<jats:italic>F<\/jats:italic><jats:sub>eNO<\/jats:sub>decreased from a geometric mean of 28.2 to 25.7\u2005ppb, and, in subjects with an elevated (&gt;35\u2005ppb) baseline<jats:italic>F<\/jats:italic><jats:sub>eNO<\/jats:sub>(n\u200a=\u200a32), from 59.7 to 49.2\u2005ppb. The corresponding changes in the control group were 25.6<jats:italic>versus<\/jats:italic>27.7\u2005ppb and 49.5<jats:italic>versus<\/jats:italic>48.1\u2005ppb. Spirometric results were unaltered in the two groups.<\/jats:p><jats:p>Thus exhaled nitric oxide fraction, a marker of allergic airway inflammation, indicated a beneficial effect of a short-term educational intervention in farmers with occupational asthma. This suggests a potential for exhaled nitric oxide fraction in assessing the efficacy of preventive measures within a short time with higher sensitivity than spirometry.<\/jats:p>","DOI":"10.1183\/09031936.00023807","type":"journal-article","created":{"date-parts":[[2007,8,31]],"date-time":"2007-08-31T17:28:28Z","timestamp":1188581308000},"page":"545-548","source":"Crossref","is-referenced-by-count":33,"title":["Educational intervention decreases exhaled nitric oxide in farmers with occupational asthma"],"prefix":"10.1183","volume":"30","author":[{"given":"H.","family":"Dressel","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Gross","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"de la Motte","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"S\u00fcltz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. 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