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Time trends in prevalence were estimated using Poisson regression models in the centres that repeated the survey at different points in time.<\/jats:p><jats:p>From 1991 to 2010, the median prevalence of current asthma, wheezing and allergic rhinitis increased from 4.1% to 6.6%, from 10.1% to 13.9% and from 16.8% to 25.8%, respectively. The prevalence of current asthma was stable during the 1990s and increased (relative risk 1.38, 95% CI 1.19\u20131.59) from 1998\u20132000 to 2007\u20132010, mainly in subjects who did not report allergic rhinitis. The prevalence of allergic rhinitis has increased continuously since 1991.<\/jats:p><jats:p>The asthma epidemic is not over in Italy. 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