{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T11:24:49Z","timestamp":1787311489500,"version":"build-2736575974"},"reference-count":39,"publisher":"European Respiratory Society (ERS)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur Respir J"],"accepted":{"date-parts":[[2007,9,10]]},"published-print":{"date-parts":[[2008,2]]},"abstract":"<jats:p>The aim of the present study was to explore morbidity and healthcare utilisation among young adult males with obstructive sleep apnoea (OSA) compared with middle-aged OSA patients over the 5-yr period preceding diagnosis.<\/jats:p>\n                  <jats:p>A prospective case\u2013control study was performed; 117 young (22\u201339-yr-old) males with OSA were matched with 117 middle-aged (40\u201364-yr-old) OSA males for body mass index, apnoea\/hypopnoea index, arterial oxygen saturation, arousal and awakening index, and Epworth Sleepiness Scale score. Each OSA patient was matched with controls by age, geographic area and physician.<\/jats:p>\n                  <jats:p>\n                    Young adult males with OSA showed no increase in specific comorbidity compared with controls. Middle-aged OSA patients exhibited increased risk of cardiovascular disease. Healthcare utilisation for the 5-yr period was \u22651.9 times higher among young and middle-aged male OSA patients than among controls. Multiple logistic regression analysis revealed that hyperlipidaemia in young adults and a body mass index of &gt;37\u2005kg\u00b7m\n                    <jats:sup>\u22122<\/jats:sup>\n                    and cardiovascular disease in middle-aged adults are the only independent determinants of the upper third, most costly, OSA patients.\n                  <\/jats:p>\n                  <jats:p>Compared with middle-aged males with obstructive sleep apnoea, in whom increased expenditure was related to cardiovascular disease and body mass index, utilisation was not related to any specific disease in younger cases.<\/jats:p>","DOI":"10.1183\/09031936.00097907","type":"journal-article","created":{"date-parts":[[2007,9,26]],"date-time":"2007-09-26T20:25:54Z","timestamp":1190838354000},"page":"273-279","source":"Crossref","is-referenced-by-count":30,"title":["Elevated healthcare utilisation in young adult males with obstructive sleep apnoea"],"prefix":"10.1183","volume":"31","author":[{"given":"H.","family":"Reuveni","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Greenberg-Dotan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Simon-Tuval","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Oksenberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Tarasiuk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"81","published-online":{"date-parts":[[2007,9,26]]},"reference":[{"key":"2024102019244062000_31.2.273.1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.121.1.164"},{"key":"2024102019244062000_31.2.273.2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.130.3.766"},{"key":"2024102019244062000_31.2.273.3","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200005113421901"},{"key":"2024102019244062000_31.2.273.4","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000154540.62381.CF"},{"key":"2024102019244062000_31.2.273.5","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.163.1.2001008"},{"key":"2024102019244062000_31.2.273.6","doi-asserted-by":"publisher","DOI":"10.1001\/jama.283.14.1829"},{"key":"2024102019244062000_31.2.273.7","doi-asserted-by":"crossref","first-page":"740","DOI":"10.1093\/sleep\/22.6.740","volume":"22","year":"1999","journal-title":"Sleep"},{"key":"2024102019244062000_31.2.273.8","doi-asserted-by":"crossref","first-page":"1306","DOI":"10.1093\/sleep\/28.10.1306","volume":"28","year":"2005","journal-title":"Sleep"},{"key":"2024102019244062000_31.2.273.9","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1093\/sleep\/22.6.749","volume":"22","year":"1999","journal-title":"Sleep"},{"key":"2024102019244062000_31.2.273.10","doi-asserted-by":"publisher","DOI":"10.1136\/thorax.57.5.417"},{"key":"2024102019244062000_31.2.273.11","doi-asserted-by":"publisher","DOI":"10.1378\/chest.128.3.1310"},{"key":"2024102019244062000_31.2.273.12","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1093\/sleep\/22.2.225","volume":"22","year":"1999","journal-title":"Sleep"},{"key":"2024102019244062000_31.2.273.13","doi-asserted-by":"crossref","first-page":"207","DOI":"10.5664\/jcsm.26517","volume":"2","year":"2006","journal-title":"J Clin Sleep Med"},{"key":"2024102019244062000_31.2.273.14","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1093\/sleep\/14.6.540","volume":"14","year":"1991","journal-title":"Sleep"},{"key":"2024102019244062000_31.2.273.15","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1093\/sleep\/26.6.747","volume":"26","year":"2003","journal-title":"Sleep"},{"key":"2024102019244062000_31.2.273.16","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.01.00038101"},{"key":"2024102019244062000_31.2.273.17","first-page":"835","volume":"20","year":"1997","journal-title":"Sleep"},{"key":"2024102019244062000_31.2.273.18","unstructured":"Central Bureau of Statistics. 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