{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T21:03:06Z","timestamp":1783976586083,"version":"3.55.0"},"reference-count":33,"publisher":"European Respiratory Society (ERS)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur Respir J"],"accepted":{"date-parts":[[2010,8,19]]},"published-print":{"date-parts":[[2011,5]]},"abstract":"<jats:p>The aim of the present study was to estimate slow-wave activity (SWA), a marker of sleep homeostasis, in children with obstructive sleep apnoea (OSA) before and after adenotonsillectomy (AT) compared with untreated OSA children (comparison group).<\/jats:p><jats:p>14 children with OSA (mean\u00b1<jats:sc>sd<\/jats:sc>age 6.4\u00b12.5 yrs; apnoea\u2013hypopnoea index (AHI) 10.0\u00b110.3 events\u00b7h<jats:sup>\u22121<\/jats:sup>) who underwent AT were consecutively recruited to the study. The comparison group comprised six retrospectively recruited children (age 5.4\u00b12.2 yrs; AHI 9.4\u00b17.6 events\u00b7h<jats:sup>\u22121<\/jats:sup>) with OSA that did not undergo treatment. Electroencephalogram (derivation C3\/A2) was analysed using spectral and waveform analysis to determine SWA energy and slow-wave slope. The same procedure was repeated 5.4 and 19 months later for the AT and comparison groups, respectively.<\/jats:p><jats:p>AT improved respiration without a change in duration of sleep stages. Following AT, &gt;50% elevation of SWA during the first two sleep cycles (p&lt;0.01) and a more physiological decay of SWA across the night (p&lt;0.0001) were noted. The slow-wave slope increased by &gt;30% following AT (p&lt;0.03). No significant changes were found in SWA in the comparison group.<\/jats:p><jats:p>Sleep homeostasis is considerably impaired in pre-pubescent children with OSA. AT restores more physiological sleep homeostasis in children with OSA. SWA analysis may provide a useful addition to standard sleep-stage analyses in children with OSA.<\/jats:p>","DOI":"10.1183\/09031936.00106710","type":"journal-article","created":{"date-parts":[[2010,9,4]],"date-time":"2010-09-04T00:46:18Z","timestamp":1283561178000},"page":"1144-1150","source":"Crossref","is-referenced-by-count":29,"title":["Adenotonsillectomy improves slow-wave activity in children with obstructive sleep apnoea"],"prefix":"10.1183","volume":"37","author":[{"given":"N.","family":"Ben-Israel","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.","family":"Zigel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Tal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.","family":"Segev","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Tarasiuk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"81","published-online":{"date-parts":[[2010,9,3]]},"reference":[{"key":"2024102020261008000_37.5.1144.1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.124.3.948"},{"key":"2024102020261008000_37.5.1144.2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(99)70331-8"},{"key":"2024102020261008000_37.5.1144.3","doi-asserted-by":"crossref","first-page":"999","DOI":"10.1093\/sleep\/26.8.999","article-title":"Adenotonsillectomy improves neurocognitive function in children with obstructive sleep apnea syndrome","volume":"26","author":"Friedman","year":"2003","journal-title":"Sleep"},{"key":"2024102020261008000_37.5.1144.4","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(94)70007-9"},{"key":"2024102020261008000_37.5.1144.5","doi-asserted-by":"publisher","DOI":"10.1542\/peds.113.2.351"},{"key":"2024102020261008000_37.5.1144.6","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.162.2.9908058"},{"key":"2024102020261008000_37.5.1144.7","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200912-1930OC"},{"key":"2024102020261008000_37.5.1144.8","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2006.08.067"},{"key":"2024102020261008000_37.5.1144.9","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.05.00082904"},{"key":"2024102020261008000_37.5.1144.10","doi-asserted-by":"crossref","first-page":"1325","DOI":"10.1093\/sleep\/32.10.1325","article-title":"Sleep stage dynamics differ between children with and without obstructive sleep apnea","volume":"32","author":"Chervin","year":"2009","journal-title":"Sleep"},{"key":"2024102020261008000_37.5.1144.11","first-page":"195","article-title":"A two-process model of sleep regulation","volume":"1","author":"Borbely","year":"1982","journal-title":"Hum Neurobiol"},{"key":"2024102020261008000_37.5.1144.12","doi-asserted-by":"crossref","unstructured":"Tononi G . 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