{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T23:57:23Z","timestamp":1793836643739,"version":"4.6.1"},"reference-count":32,"publisher":"European Respiratory Society (ERS)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur Respir J"],"accepted":{"date-parts":[[2009,12,1]]},"published-print":{"date-parts":[[2010,7]]},"abstract":"<jats:p>The aim of this study was to evaluate the impact of urban air pollution, assessed through reliable indicators of exposure, on asthma and allergies in schoolchildren.<\/jats:p><jats:p>A validated dispersion model combining data on traffic conditions, topography, meteorology and background pollution was used to relate 3-yrs averaged concentrations of major urban pollutants at the sites of schools to skin prick tests, exercise-induced asthma and reported asthma and allergies in 6,683 children (9\u201311 yrs) attending 108 schools randomly selected in six French communities.<\/jats:p><jats:p>For the 4,907 children who had resided at their current address for the past 3 yrs, asthma (exercise induced, past year and lifetime) was significantly positively associated with benzene, SO<jats:sub>2<\/jats:sub>, particles with a 50% cut-off aerodynamic diameter of 10 \u03bcm (PM<jats:sub>10<\/jats:sub>), nitrogen oxides (NO<jats:sub>x<\/jats:sub>) and CO. In the same children, eczema (lifetime and past year) was significantly positively associated with benzene, PM<jats:sub>10<\/jats:sub>, NO<jats:sub>2<\/jats:sub>, NO<jats:sub>x<\/jats:sub>and CO, lifetime allergic rhinitis with PM<jats:sub>10<\/jats:sub>and sensitisation to pollens with benzene and PM<jats:sub>10<\/jats:sub>. Among the 2,213 children residing at their current address since birth, the associations persisted for lifetime asthma with benzene (adjusted OR per interquartile range (95% CI) 1.3 (1.0\u20131.9)) and PM<jats:sub>10<\/jats:sub>(1.4 (1.0\u20132.0)), and for sensitisation to pollens with volatile organic compounds (1.3 (1.0\u20131.9)) and PM<jats:sub>10<\/jats:sub>(1.2 (1.0\u20131.9)).<\/jats:p><jats:p>Accurately modelled urban air pollution was associated with some measures of childhood asthma and allergies.<\/jats:p>","DOI":"10.1183\/09031936.00116109","type":"journal-article","created":{"date-parts":[[2010,1,15]],"date-time":"2010-01-15T01:33:26Z","timestamp":1263519206000},"page":"33-40","source":"Crossref","is-referenced-by-count":270,"title":["Long-term exposure to close-proximity air pollution and asthma and allergies in urban 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