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The challenges posed by unmasked TB, such as its high incidence, the lack of reliable diagnostic tools and the uncertainties on its optimal management, may hamper our ability to face the TB\/HIV epidemic. Therefore, unmasked TB appears a major threat to global health and poses additional barriers to successful HIV\/AIDS care and treatment programmes.<\/jats:p><jats:p>This review focuses on the epidemiology, immunopathogenesis and clinical manifestations of unmasked TB, and provides evidence-based recommendations for management and care of the disease.<\/jats:p>","DOI":"10.1183\/09031936.00116611","type":"journal-article","created":{"date-parts":[[2011,10,18]],"date-time":"2011-10-18T04:27:52Z","timestamp":1318912072000},"page":"1064-1075","source":"Crossref","is-referenced-by-count":13,"title":["Unmasking tuberculosis in the era of antiretroviral 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