{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T02:19:47Z","timestamp":1787019587891,"version":"build-2736575974"},"reference-count":33,"publisher":"European Respiratory Society (ERS)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur Respir J"],"accepted":{"date-parts":[[2008,11,4]]},"published-print":{"date-parts":[[2009,3]]},"abstract":"<jats:p>Hypertension develops in 10% of pregnancies. Snoring, a marker of obstructive sleep apnoea, is a newly identified risk factor for gestational hypertension. Moreover, obstructive sleep apnoea is an independent risk factor for incident hypertension in the non-pregnant population. The aim of the present study was to test the hypothesis that obstructive sleep apnoea is associated with new onset of hypertension among pregnant females.<\/jats:p>\n                  <jats:p>\n                    A case\u2013control study was performed involving 17 pregnant females with gestational hypertension and 33 pregnant females without hypertension. Subjects were frequency-matched for gestational age and recruited in a tertiary obstetrical centre. Obstructive sleep apnoea was ascertained by polysomnography and defined by an apnoea\/hypopnoea index (AHI) of \u226515\u2005events\u00b7h\n                    <jats:sup>\u22121<\/jats:sup>\n                    , without requirement for desaturation.\n                  <\/jats:p>\n                  <jats:p>\n                    The mean\u00b1\n                    <jats:sc>sd<\/jats:sc>\n                    AHI for normotensive pregnant females was 18.2\u00b112.2\u2005events\u00b7h\n                    <jats:sup>\u22121<\/jats:sup>\n                    compared with 38.6\u00b136.7\u2005events\u00b7h\n                    <jats:sup>\u22121<\/jats:sup>\n                    for females with hypertensive pregnancies. The crude odds ratio for the presence of obstructive sleep apnoea given the presence of gestational hypertension was 5.6. The odds ratio was 7.5 (95% confidence interval 3.5\u201316.2), based on a logistic regression model with adjustment for maternal age, gestational age, pre-pregnancy body mass index, prior pregnancies, and previous live births.\n                  <\/jats:p>\n                  <jats:p>In conclusion, gestational hypertension appears to be strongly associated with the presence of obstructive sleep apnoea.<\/jats:p>","DOI":"10.1183\/09031936.00122607","type":"journal-article","created":{"date-parts":[[2009,2,12]],"date-time":"2009-02-12T20:25:56Z","timestamp":1234470356000},"page":"559-565","source":"Crossref","is-referenced-by-count":106,"title":["Obstructive sleep apnoea and its association with gestational hypertension"],"prefix":"10.1183","volume":"33","author":[{"given":"K.","family":"Champagne","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Schwartzman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Opatrny","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Barriga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Morin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Mallozzi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Benjamin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. 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