{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T11:10:40Z","timestamp":1790680240181,"version":"4.1.0"},"reference-count":30,"publisher":"European Respiratory Society (ERS)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur Respir J"],"accepted":{"date-parts":[[2009,3,23]]},"published-print":{"date-parts":[[2009,9]]},"abstract":"<jats:p>Some patients with obstructive sleep apnoea syndrome (OSAS; respiratory distress index (RDI) of &gt;5\u2005events\u00b7h<jats:sup>\u22121<\/jats:sup>) experience residual excessive daytime subjective sleepiness (Epworth Sleepiness Scale (ESS) score of &gt;10), despite adequate use of continuous positive airway pressure (CPAP) therapy. The aim of the present study was to identify clinical and polysomnographic predictors of this sleepiness.<\/jats:p><jats:p>Clinical and polysomnographic variables and ESS score were evaluated in 208 OSAS patients with an ESS score of &gt;10 before (initial assessment) and after \u22656\u2005months of adequate (\u22654\u2005h\u00b7day<jats:sup>\u22121<\/jats:sup>) CPAP use.<\/jats:p><jats:p>Following CPAP treatment, 114 (55%) patients showed an abnormal ESS score (&gt;10; CPAP nonresponders), whereas 94 (45%) showed a normal ESS score (&lt;11; CPAP responders). Of the CPAP responders, none had a history of depression, whereas the converse was true for 38.8% of CPAP nonresponders. In addition, multivariate logistic regression analysis revealed that the independent predictors of residual excessive daytime sleepiness following CPAP therapy were a history of diabetes and heart disease, and a higher ESS score and lower RDI on initial assessment.<\/jats:p><jats:p>In conclusion, predictors of residual excessive sleepiness in adequately CPAP-treated OSAS were a history of depression, diabetes and heart disease, and a higher ESS score and lower RDI on initial assessment.<\/jats:p>","DOI":"10.1183\/09031936.00124708","type":"journal-article","created":{"date-parts":[[2009,4,9]],"date-time":"2009-04-09T00:44:59Z","timestamp":1239237899000},"page":"687-693","source":"Crossref","is-referenced-by-count":89,"title":["Predictors of residual sleepiness in adequately treated obstructive sleep apnoea patients"],"prefix":"10.1183","volume":"34","author":[{"given":"I.","family":"Koutsourelakis","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Perraki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N. 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