{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T10:45:30Z","timestamp":1777632330746,"version":"3.51.4"},"reference-count":14,"publisher":"European Respiratory Society (ERS)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur Respir J"],"accepted":{"date-parts":[[2010,10,18]]},"published-print":{"date-parts":[[2011,7]]},"abstract":"<jats:p>We compared clinical presentation, complications and outcome in patients with influenza A (H1N1) and seasonal influenza pneumonia.<\/jats:p><jats:p>The group of patients with influenza A (H1N1) pneumonia consisted of 75 patients. 52 patients with pneumonia associated with seasonal influenza were included for comparison.<\/jats:p><jats:p>Patients with pneumonia associated with novel H1N1 influenza were younger (mean age 39.7 yrs<jats:italic>versus<\/jats:italic>69.6 yrs) and had fewer chronic comorbidities and less alcoholism. Infiltrates were more extensive and frequently interstitial. Respiratory failure was more frequent (those with an arterial oxygen tension\/inspiratory oxygen fraction ratio &lt;200 28%<jats:italic>versus<\/jats:italic>12%, p = 0.042), leading to a higher rate of intensive care unit (ICU) admission and mechanical ventilation (29.3%<jats:italic>versus<\/jats:italic>7.7% (p&lt;0.0030) and 18.7%<jats:italic>versus<\/jats:italic>2% (p&lt;0.0045)). Mortality was twice as high in patients with novel H1N1 (12%<jats:italic>versus<\/jats:italic>5.8%; p = 0.238), although this was not significant, and was attributable to pneumonia in most instances (77.8%<jats:italic>versus<\/jats:italic>0%; p = 0.046).<\/jats:p><jats:p>Younger age, fewer comorbidities, more extensive radiographic extension and more severe respiratory compromise, and ICU admissions are key features of the clinical presentation of patients with novel H1N1-associated pneumonia compared with seasonal influenza pneumonia.<\/jats:p>","DOI":"10.1183\/09031936.00125910","type":"journal-article","created":{"date-parts":[[2010,11,26]],"date-time":"2010-11-26T01:55:03Z","timestamp":1290736503000},"page":"106-111","source":"Crossref","is-referenced-by-count":25,"title":["Influenza pneumonia: a comparison between seasonal influenza virus and the H1N1 pandemic"],"prefix":"10.1183","volume":"38","author":[{"given":"R.","family":"Riquelme","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Torres","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.L.","family":"Rioseco","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Ewig","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Cill\u00f3niz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Riquelme","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Inzunza","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Polverino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y.","family":"Gomez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.A.","family":"Marcos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Contreras","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Gabarr\u00fas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Fasce","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"81","published-online":{"date-parts":[[2010,11,25]]},"reference":[{"key":"2024102020331557000_38.1.106.1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cger.2007.02.002"},{"key":"2024102020331557000_38.1.106.2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1750-2659.2009.00073.x"},{"key":"2024102020331557000_38.1.106.3","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0904252"},{"key":"2024102020331557000_38.1.106.4","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0904023"},{"key":"2024102020331557000_38.1.106.5","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199701233360402"},{"key":"2024102020331557000_38.1.106.6","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.06.00062505"},{"key":"2024102020331557000_38.1.106.7","doi-asserted-by":"publisher","DOI":"10.1136\/thx.2008.109785"},{"key":"2024102020331557000_38.1.106.8","doi-asserted-by":"crossref","unstructured":"Hosmer DW Lemeshow S . 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