{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T02:20:42Z","timestamp":1787019642089,"version":"build-2736575974"},"reference-count":50,"publisher":"European Respiratory Society (ERS)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur Respir J"],"accepted":{"date-parts":[[2008,3,3]]},"published-print":{"date-parts":[[2008,7]]},"abstract":"<jats:p>Increasing evidence supports the use of embolisation to treat pulmonary arteriovenous malformations (AVMs). Most pulmonary AVM patients have hereditary haemorrhagic telangiectasia (HHT), a condition that may be associated with pulmonary hypertension.<\/jats:p>\n                  <jats:p>\n                    The current authors tested whether pulmonary AVM embolisation increases pulmonary artery pressure (\n                    <jats:italic>P<\/jats:italic>\n                    <jats:sub>pa<\/jats:sub>\n                    ) in patients without baseline severe pulmonary hypertension.\n                    <jats:italic>P<\/jats:italic>\n                    <jats:sub>pa<\/jats:sub>\n                    was measured at the time of pulmonary AVM embolisation in 143 individuals, 131 (92%) of whom had underlying HHT. Angiography\/embolisation was not performed in four individuals with severe pulmonary hypertension, whose systemic arterial oxygen saturation exceeded levels usually associated with dyspnoea in pulmonary AVM patients.\n                  <\/jats:p>\n                  <jats:p>\n                    In 143 patients undergoing pulmonary AVM embolisation,\n                    <jats:italic>P<\/jats:italic>\n                    <jats:sub>pa<\/jats:sub>\n                    was significantly correlated with age, with the most significant increase occurring in the upper quartile (aged &gt;58\u2005yrs). In 43 patients with repeated measurements, there was no significant increase in\n                    <jats:italic>P<\/jats:italic>\n                    <jats:sub>pa<\/jats:sub>\n                    as a result of embolisation. In half, embolisation led to a fall in\n                    <jats:italic>P<\/jats:italic>\n                    <jats:sub>pa<\/jats:sub>\n                    . The maximum rise in mean\n                    <jats:italic>P<\/jats:italic>\n                    <jats:sub>pa<\/jats:sub>\n                    was 8\u2005mmHg: balloon test occlusion was performed in one of these individuals, and did not predict the subsequent rise in\n                    <jats:italic>P<\/jats:italic>\n                    <jats:sub>pa<\/jats:sub>\n                    following definitive embolisation of the pulmonary AVMs.\n                  <\/jats:p>\n                  <jats:p>In the present series of patients, which excluded those with severe pulmonary hypertension, pulmonary artery pressure was not increased significantly by pulmonary arteriovenous malformation embolisation.<\/jats:p>","DOI":"10.1183\/09031936.00126207","type":"journal-article","created":{"date-parts":[[2008,4,2]],"date-time":"2008-04-02T20:26:58Z","timestamp":1207168018000},"page":"162-169","source":"Crossref","is-referenced-by-count":67,"title":["Embolisation of pulmonary arteriovenous malformations: no consistent effect on pulmonary artery pressure"],"prefix":"10.1183","volume":"32","author":[{"given":"C. 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