{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T13:02:28Z","timestamp":1792587748717,"version":"4.5.0"},"reference-count":30,"publisher":"European Respiratory Society (ERS)","issue":"1","content-domain":{"domain":["publications.ersnet.org"],"crossmark-restriction":true},"short-container-title":["Eur Respir J"],"accepted":{"date-parts":[[2014,7,24]]},"published-print":{"date-parts":[[2015,1]]},"abstract":"<jats:p>The chronic impact of ambient air pollutants on lung function in adults is not fully understood. The objective of this study was to investigate the association of long-term exposure to ambient air pollution with lung function in adult participants from five cohorts in the European Study of Cohorts for Air Pollution Effects (ESCAPE).<\/jats:p>\n                  <jats:p>\n                    Residential exposure to nitrogen oxides (NO\n                    <jats:sub>2<\/jats:sub>\n                    , NO\n                    <jats:sub>x<\/jats:sub>\n                    ) and particulate matter (PM) was modelled and traffic indicators were assessed in a standardised manner. The spirometric parameters forced expiratory volume in 1 s (FEV\n                    <jats:sub>1<\/jats:sub>\n                    ) and forced vital capacity (FVC) from 7613 subjects were considered as outcomes. Cohort-specific results were combined using meta-analysis.\n                  <\/jats:p>\n                  <jats:p>\n                    We did not observe an association of air pollution with longitudinal change in lung function, but we observed that a 10 \u03bcg\u00b7m\n                    <jats:sup>\u22123<\/jats:sup>\n                    increase in NO\n                    <jats:sub>2<\/jats:sub>\n                    exposure was associated with lower levels of FEV\n                    <jats:sub>1<\/jats:sub>\n                    (\u221214.0 mL, 95% CI \u221225.8 to \u22122.1) and FVC (\u221214.9 mL, 95% CI \u221228.7 to \u22121.1). An increase of 10 \u03bcg\u00b7m\n                    <jats:sup>\u22123<\/jats:sup>\n                    in PM\n                    <jats:sub>10<\/jats:sub>\n                    , but not other PM metrics (PM\n                    <jats:sub>2.5<\/jats:sub>\n                    , coarse fraction of PM, PM absorbance), was associated with a lower level of FEV\n                    <jats:sub>1<\/jats:sub>\n                    (\u221244.6 mL, 95% CI \u221285.4 to \u22123.8) and FVC (\u221259.0 mL, 95% CI \u2212112.3 to \u22125.6). The associations were particularly strong in obese persons.\n                  <\/jats:p>\n                  <jats:p>This study adds to the evidence for an adverse association of ambient air pollution with lung function in adults at very low levels in Europe.<\/jats:p>","DOI":"10.1183\/09031936.00130014","type":"journal-article","created":{"date-parts":[[2014,9,6]],"date-time":"2014-09-06T01:20:59Z","timestamp":1409966459000},"page":"38-50","update-policy":"https:\/\/doi.org\/10.1183\/ers-crossmark-policy","source":"Crossref","is-referenced-by-count":342,"title":["Adult lung function and long-term air pollution exposure. 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