{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,6]],"date-time":"2026-07-06T12:21:44Z","timestamp":1783340504630,"version":"3.54.6"},"reference-count":30,"publisher":"European Respiratory Society (ERS)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur Respir J"],"accepted":{"date-parts":[[2012,9,16]]},"published-print":{"date-parts":[[2013,5]]},"abstract":"<jats:p>Hyperventilation and other clinical manifestations of dysfunctional breathing have been reported in childhood, but the prevalence is unknown. In adults, dysfunctional breathing may be a relevant comorbidity in asthma. We aimed to determine the prevalence of dysfunctional breathing in children with asthma and its impact on asthma control.<\/jats:p><jats:p>We performed a cross-sectional survey in 203 asthmatic children (aged 5\u201318 years), using the Nijmegen Questionnaire and the paediatric Asthma Control Questionnaire.<\/jats:p><jats:p>Dysfunctional breathing was found in 11 (5.3%) children; more females (eight (12.9%) out of 62) than males (three (2.1%) out 144, p=0.002). There was a dose\u2013dependent relationship between increasing Nijmegen Questionnaire scores (increased risk of dysfunctional breathing) and poorer asthma control. Poor asthma control was more common in patients with dysfunctional breathing (10 (90.9%) out of 11 children) than in children without (65 (32.3%) out of 192 children; OR 19.3, 95% CI 3.14\u2013430.70; p&lt;0.0001). The median Asthma Control Questionnaire in children with dysfunctional breathing was higher (median (range) 2.00 (1.50\u20133.17)) than in children without (0.50 (0.17\u20131.17); p&lt;0.001).<\/jats:p><jats:p>The prevalence of dysfunctional breathing in children and adolescents referred to a hospital-based paediatric asthma clinic for severe or difficult-to-control asthma is 5%. The association between dysfunctional breathing and asthma control suggests that this may be a clinically relevant comorbidity in paediatric asthma.<\/jats:p>","DOI":"10.1183\/09031936.00130212","type":"journal-article","created":{"date-parts":[[2012,9,28]],"date-time":"2012-09-28T19:31:43Z","timestamp":1348860703000},"page":"1068-1073","source":"Crossref","is-referenced-by-count":62,"title":["Dysfunctional breathing in children with asthma: a rare but relevant comorbidity"],"prefix":"10.1183","volume":"41","author":[{"given":"Eric P.","family":"de Groot","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric J.","family":"Duiverman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul L.P.","family":"Brand","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"81","published-online":{"date-parts":[[2012,9,27]]},"reference":[{"issue":"Suppl. 2","key":"2024102021211126000_41.5.1068.1","first-page":"II31","article-title":"Dysfunctional breathing in asthma: is it common, identifiable and correctable","volume":"57","author":"Morgan","year":"2002","journal-title":"Thorax"},{"key":"2024102021211126000_41.5.1068.2","doi-asserted-by":"publisher","DOI":"10.1136\/thorax.58.2.110"},{"key":"2024102021211126000_41.5.1068.3","doi-asserted-by":"publisher","DOI":"10.1016\/j.prrv.2010.09.003"},{"key":"2024102021211126000_41.5.1068.4","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(67)80035-0"},{"key":"2024102021211126000_41.5.1068.5","doi-asserted-by":"publisher","DOI":"10.1016\/j.arcped.2005.09.015"},{"key":"2024102021211126000_41.5.1068.6","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1542\/peds.67.2.183","article-title":"Hyperventilation syndrome in children and adolescents: long-term follow-up","volume":"67","author":"Herman","year":"1981","journal-title":"Pediatrics"},{"key":"2024102021211126000_41.5.1068.7","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1007\/BF03061476","article-title":"Inspanningsgebonden benauwdheid bij kinderen: disfunctionele ademhaling","volume":"72","author":"Brouwer","year":"2004","journal-title":"Tijdschr Kindergeneeskd"},{"key":"2024102021211126000_41.5.1068.8","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1016\/S1081-1206(10)60989-1","article-title":"Exercise induced dyspnea in children and adolescents: if not asthma then what","volume":"94","author":"Abu-Hassan","year":"2005","journal-title":"Ann Allergy Asthma Immunol"},{"key":"2024102021211126000_41.5.1068.9","doi-asserted-by":"publisher","DOI":"10.1136\/adc.2004.063974"},{"key":"2024102021211126000_41.5.1068.10","unstructured":"Global strategy for asthma management and prevention. Global Initiative for Asthma (GINA) 2012. Available from: www.ginasthma.org ."},{"key":"2024102021211126000_41.5.1068.11","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/ppul.21321","article-title":"Global strategy for the diagnosis and management of asthma in children 5 years and younger","volume":"46","author":"Pedersen","year":"2011","journal-title":"Pediatr Pulmonol"},{"key":"2024102021211126000_41.5.1068.12","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3999(85)90042-X"},{"key":"2024102021211126000_41.5.1068.13","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.322.7294.1098"},{"key":"2024102021211126000_41.5.1068.14","doi-asserted-by":"publisher","DOI":"10.1016\/j.pcrj.2004.10.007"},{"key":"2024102021211126000_41.5.1068.15","doi-asserted-by":"publisher","DOI":"10.1034\/j.1399-3003.1999.14a08.x"},{"key":"2024102021211126000_41.5.1068.16","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00117509"},{"key":"2024102021211126000_41.5.1068.17","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmed.2005.08.012"},{"key":"2024102021211126000_41.5.1068.18","doi-asserted-by":"publisher","DOI":"10.1378\/chest.129.6.1478"},{"key":"2024102021211126000_41.5.1068.19","doi-asserted-by":"publisher","DOI":"10.1183\/09041950.005s1693"},{"key":"2024102021211126000_41.5.1068.20","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200708-1248OC"},{"key":"2024102021211126000_41.5.1068.21","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200406-710ST"},{"key":"2024102021211126000_41.5.1068.22","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2006.03.013"},{"key":"2024102021211126000_41.5.1068.23","doi-asserted-by":"publisher","DOI":"10.1136\/thoraxjnl-2011-201168"},{"key":"2024102021211126000_41.5.1068.24","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(08)61422-1"},{"key":"2024102021211126000_41.5.1068.25","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00185709"},{"key":"2024102021211126000_41.5.1068.26","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3999(75)90017-3"},{"key":"2024102021211126000_41.5.1068.27","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(50)90093-3"},{"key":"2024102021211126000_41.5.1068.28","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmed.2011.03.006"},{"key":"2024102021211126000_41.5.1068.29","doi-asserted-by":"publisher","DOI":"10.1378\/chest.130.6.1723"},{"key":"2024102021211126000_41.5.1068.30","doi-asserted-by":"publisher","DOI":"10.1136\/thx.2007.093989"}],"container-title":["European Respiratory Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1183\/09031936.00130212","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,24]],"date-time":"2025-02-24T06:40:25Z","timestamp":1740379225000},"score":1,"resource":{"primary":{"URL":"https:\/\/publications.ersnet.org\/lookup\/doi\/10.1183\/09031936.00130212"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,9,27]]},"references-count":30,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2013,4,30]]},"published-print":{"date-parts":[[2013,5]]}},"alternative-id":["10.1183\/09031936.00130212"],"URL":"https:\/\/doi.org\/10.1183\/09031936.00130212","relation":{},"ISSN":["0903-1936","1399-3003"],"issn-type":[{"value":"0903-1936","type":"print"},{"value":"1399-3003","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,9,27]]}}}