{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T06:31:14Z","timestamp":1787985074584,"version":"build-2784847793"},"reference-count":27,"publisher":"European Respiratory Society (ERS)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur Respir J"],"accepted":{"date-parts":[[2014,4,4]]},"published-print":{"date-parts":[[2014,9]]},"abstract":"<jats:p>The aim of the study was to investigate the prognostic value of right heart catheterisation variables measured during exercise.<\/jats:p><jats:p>55 incident patients with idiopathic, familial or anorexigen-associated pulmonary arterial hypertension (PAH) underwent right heart catheterisation at rest and during exercise and 6-min walk testing before PAH treatment initiation. Patients were treated according to recommendations within the next 2 weeks. Right heart catheterisation was repeated 3\u20135 months into the PAH treatment in 20 patients.<\/jats:p><jats:p>Exercise cardiac index decreased gradually as New York Heart Association (NYHA) functional class increased whereas cardiac index at rest was not significantly different across NYHA groups. Baseline 6-min walk distance correlated significantly with exercise and change in cardiac index from rest to exercise (r=0.414 and r=0.481, respectively; p&lt;0.01). Change in 6-min walk distance from baseline to 3\u20135 months under PAH treatment was highly correlated with change in exercise cardiac index (r=0.746, p&lt;0.001). The most significant baseline covariates associated with survival were change in systolic pulmonary artery pressure from rest to exercise and exercise cardiac index (hazard ratio 0.56 (95% CI 0.37\u20130.86) and 0.14 (95% CI 0.05\u20130.43), respectively).<\/jats:p><jats:p>Change in pulmonary haemodynamics during exercise is an important tool for assessing disease severity and may help devise optimal treat-to-target strategies.<\/jats:p>","DOI":"10.1183\/09031936.00153613","type":"journal-article","created":{"date-parts":[[2014,5,16]],"date-time":"2014-05-16T01:47:53Z","timestamp":1400204873000},"page":"704-713","source":"Crossref","is-referenced-by-count":73,"title":["Prognostic value of exercise pulmonary haemodynamics in pulmonary arterial hypertension"],"prefix":"10.1183","volume":"44","author":[{"given":"Ari","family":"Chaouat","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olivier","family":"Sitbon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Magalie","family":"Mercy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rapha\u00eblle","family":"Pon\u00e7ot-Mongars","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steeve","family":"Provencher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"Guillaumot","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emmanuel","family":"Gomez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine","family":"Selton-Suty","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pascale","family":"Malvestio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denis","family":"Regent","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christophe","family":"Paris","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philippe","family":"Herv\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fran\u00e7ois","family":"Chabot","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"81","published-online":{"date-parts":[[2014,5,15]]},"reference":[{"key":"2024102022485412000_44.3.704.1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2013.10.029"},{"key":"2024102022485412000_44.3.704.2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2013.10.023"},{"key":"2024102022485412000_44.3.704.3","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00057010"},{"key":"2024102022485412000_44.3.704.4","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehl477"},{"key":"2024102022485412000_44.3.704.5","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.107.653584"},{"key":"2024102022485412000_44.3.704.6","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.106.674028"},{"key":"2024102022485412000_44.3.704.7","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2013.10.032"},{"key":"2024102022485412000_44.3.704.8","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.109.898122"},{"key":"2024102022485412000_44.3.704.9","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.109.911818"},{"key":"2024102022485412000_44.3.704.10","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000029100.82385.58"},{"key":"2024102022485412000_44.3.704.11","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(02)02012-0"},{"key":"2024102022485412000_44.3.704.12","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199602013340504"},{"key":"2024102022485412000_44.3.704.13","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehp297"},{"key":"2024102022485412000_44.3.704.14","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.165.3.2106033"},{"key":"2024102022485412000_44.3.704.15","doi-asserted-by":"publisher","DOI":"10.1378\/chest.121.5.1566"},{"key":"2024102022485412000_44.3.704.16","first-page":"A1887","article-title":"Impact of exercise pulmonary hemodynamic in idiopathic, heritable and anorexigen-associated pulmonary arterial hypertension","volume":"185","author":"Chaouat","year":"2012","journal-title":"Am J Respir Crit Care Med"},{"key":"2024102022485412000_44.3.704.17","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00009008"},{"key":"2024102022485412000_44.3.704.18","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.166.1.at1102"},{"key":"2024102022485412000_44.3.704.19","doi-asserted-by":"publisher","DOI":"10.1088\/0967-3334\/28\/1\/001"},{"key":"2024102022485412000_44.3.704.20","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.161.2.9906015"},{"key":"2024102022485412000_44.3.704.21","doi-asserted-by":"publisher","DOI":"10.1378\/chest.10-0351"},{"key":"2024102022485412000_44.3.704.22","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.06.00042705"},{"key":"2024102022485412000_44.3.704.23","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(02)01786-2"},{"key":"2024102022485412000_44.3.704.24","doi-asserted-by":"publisher","DOI":"10.1136\/thx.2009.117168"},{"key":"2024102022485412000_44.3.704.25","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00223611"},{"key":"2024102022485412000_44.3.704.26","doi-asserted-by":"publisher","DOI":"10.1161\/hc2901.093198"},{"key":"2024102022485412000_44.3.704.27","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.113.001573"}],"container-title":["European Respiratory Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1183\/09031936.00153613","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,24]],"date-time":"2025-02-24T06:50:26Z","timestamp":1740379826000},"score":1,"resource":{"primary":{"URL":"https:\/\/publications.ersnet.org\/lookup\/doi\/10.1183\/09031936.00153613"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,5,15]]},"references-count":27,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2014,8,31]]},"published-print":{"date-parts":[[2014,9]]}},"alternative-id":["10.1183\/09031936.00153613"],"URL":"https:\/\/doi.org\/10.1183\/09031936.00153613","relation":{},"ISSN":["0903-1936","1399-3003"],"issn-type":[{"value":"0903-1936","type":"print"},{"value":"1399-3003","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,5,15]]}}}