{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T06:07:44Z","timestamp":1790489264707,"version":"4.1.0"},"reference-count":36,"publisher":"European Respiratory Society (ERS)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur Respir J"],"accepted":{"date-parts":[[2009,3,16]]},"published-print":{"date-parts":[[2009,10]]},"abstract":"<jats:p>Empirically determined noninvasive ventilation (NIV) settings may not achieve optimal ventilatory support. Some ventilators include monitoring modules to assess ventilatory quality. We conducted a bench-to-bedside study to assess the ventilatory quality of the VPAP<jats:sup>TM<\/jats:sup>III-ResLink<jats:sup>TM<\/jats:sup>(ResMed, North Ryde, Australia).<\/jats:p><jats:p>We tested the accuracy of minute ventilation (MV) and leak calculations given by VPAP<jats:sup>TM<\/jats:sup>III-ResLink<jats:sup>TM<\/jats:sup>compared to those measured by a bench model at varied leak levels and ventilator settings. We systematically assessed NIV efficacy using this system from 2003 to 2006. Ventilation was considered inadequate if leak (&gt;24\u2005L\u00b7min<jats:sup>\u22121<\/jats:sup>), continuous desaturation (&gt;30% of the trace) or desaturation dips (&gt;3%) were present.<\/jats:p><jats:p>On the bench test, both methods were highly correlated (r\u200a=\u200a0.947, p&gt;0.0001 and r\u200a=\u200a0.959, p&lt;0.0001 for leak and MV, respectively). We performed 222 assessments in 169 patients (aged 66.42\u00b116\u2005yrs, 100 males). Abnormalities were detected on 147 (66%) out of 222 occasions. Leak was the most common abnormality (34.2%) followed by desaturation dips (23.8%). The most effective therapeutic solutions were a chin strap if leak was detected (61.2%) and expiratory positive airway pressure increase for desaturation dips (59.5%). In 15.7% of cases, when abnormalities persisted, a polygraphy was performed.<\/jats:p><jats:p>The systematic use of this device enables NIV to be optimised, limiting the indication of sleep studies to complex cases.<\/jats:p>","DOI":"10.1183\/09031936.00170508","type":"journal-article","created":{"date-parts":[[2009,3,27]],"date-time":"2009-03-27T00:45:36Z","timestamp":1238114736000},"page":"902-913","source":"Crossref","is-referenced-by-count":99,"title":["Evaluating noninvasive ventilation using a monitoring system coupled to a ventilator: a bench-to-bedside study"],"prefix":"10.1183","volume":"34","author":[{"given":"C.","family":"Rabec","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Georges","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N. 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