{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T11:19:50Z","timestamp":1769167190791,"version":"3.49.0"},"reference-count":25,"publisher":"European Respiratory Society (ERS)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur Respir J"],"accepted":{"date-parts":[[2013,12,17]]},"published-print":{"date-parts":[[2014,5]]},"abstract":"<jats:p>There are limited data on the evolution of obstructive sleep apnoea (OSA) during continuous positive airway pressure (CPAP) therapy and whether this treatment is required every night.<\/jats:p><jats:p>125 OSA patients with an original oxygen desaturation index (ODI) &gt;10 events per hour, established on CPAP, were asked to withdraw CPAP for four nights and performed ambulatory nocturnal pulse oximetry on the fourth night of CPAP withdrawal. An ODI &gt;10 events per hour during pulse oximetry was considered to indicate persistent OSA. Patients not experiencing recurrence of OSA underwent repeat ambulatory pulse oximetry after a further 2-week period off CPAP.<\/jats:p><jats:p>In 71% of the patients, OSA recurred after four nights of CPAP withdrawal (group 1); thus, OSA did not recur in 29% (group 2). 55% of group 2 had an ODI &gt;10 events per hour after 2 weeks off CPAP; thus, 45% remained without a recurrence. In multivariate analysis, higher original ODI, longer duration of CPAP therapy, current smoking status and larger neck circumference were independently associated with a higher ODI after four nights of CPAP withdrawal (all p&lt;0.05).<\/jats:p><jats:p>Following CPAP withdrawal, a third of CPAP-treated patients do not experience significant recurrence of oxygen desaturations after 4 days and \u223c10% do not after 2 weeks. Thus, a significant proportion of patients may be able to stop CPAP for short periods.<\/jats:p>","DOI":"10.1183\/09031936.00180213","type":"journal-article","created":{"date-parts":[[2014,2,1]],"date-time":"2014-02-01T03:41:58Z","timestamp":1391226118000},"page":"1387-1393","source":"Crossref","is-referenced-by-count":26,"title":["Is continuous positive airway pressure necessarily an everyday therapy in patients with obstructive sleep apnoea?"],"prefix":"10.1183","volume":"43","author":[{"given":"Valentina A.","family":"Rossi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Esther I.","family":"Schwarz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Konrad E.","family":"Bloch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John 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