{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T10:55:40Z","timestamp":1790506540428,"version":"4.1.0"},"reference-count":141,"publisher":"European Respiratory Society (ERS)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur Respir J"],"accepted":{"date-parts":[[2014,1,26]]},"published-print":{"date-parts":[[2014,6]]},"abstract":"<jats:p>This consensus statement provides practical recommendations for specific inhalation challenge (SIC) in the diagnosis of occupational asthma. They are derived from a systematic literature search, a census of active European centres, a Delphi conference and expert consensus. This article details each step of a SIC, including safety requirements, techniques for delivering agents, and methods for assessing and interpreting bronchial responses. The limitations of the procedure are also discussed.<\/jats:p><jats:p>Testing should only be carried out in hospitals where physicians and healthcare professionals have appropriate expertise. Tests should always include a control challenge, a gradual increase of exposure to the suspected agent, and close monitoring of the patient during the challenge and for at least 6 h afterwards. In expert centres, excessive reactions provoked by SIC are rare.<\/jats:p><jats:p>A positive response is defined by a fall in forced expiratory volume in 1 s \u226515% from baseline. Equivocal reactions can sometimes be clarified by finding changes in nonspecific bronchial responsiveness, sputum eosinophils or exhaled nitric oxide. The sensitivity and specificity of SIC are high but not easily quantified, as the method is usually used as the reference standard for the diagnosis of occupational asthma.<\/jats:p>","DOI":"10.1183\/09031936.00180313","type":"journal-article","created":{"date-parts":[[2014,3,7]],"date-time":"2014-03-07T05:10:10Z","timestamp":1394169010000},"page":"1573-1587","source":"Crossref","is-referenced-by-count":192,"title":["Specific inhalation challenge in the diagnosis of occupational asthma: consensus statement"],"prefix":"10.1183","volume":"43","author":[{"given":"Olivier","family":"Vandenplas","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hille","family":"Suojalehto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tor B.","family":"Aasen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xaver","family":"Baur","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P. Sherwood","family":"Burge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frederic","family":"de Blay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Fishwick","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Hoyle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Piero","family":"Maestrelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xavier","family":"Mu\u00f1oz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gianna","family":"Moscato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joaquin","family":"Sastre","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Torben","family":"Sigsgaard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katri","family":"Suuronen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jolanta","family":"Walusiak-Skorupa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Cullinan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"the ERS Task Force on Specific Inhalation Challenges with Occupational Agents","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"81","published-online":{"date-parts":[[2014,3,6]]},"reference":[{"key":"2024102022372319000_43.6.1573.1","doi-asserted-by":"publisher","DOI":"10.1136\/oem.2004.016287"},{"key":"2024102022372319000_43.6.1573.2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.08-0201"},{"key":"2024102022372319000_43.6.1573.3","doi-asserted-by":"publisher","DOI":"10.1016\/j.iac.2011.07.003"},{"key":"2024102022372319000_43.6.1573.4","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00096111"},{"key":"2024102022372319000_43.6.1573.5","first-page":"829","article-title":"Bronchial provocation tests in etiologic diagnosis and analysis of asthma","volume":"112","author":"Pepys","year":"1975","journal-title":"Am Rev Respir Dis"},{"key":"2024102022372319000_43.6.1573.6","doi-asserted-by":"publisher","DOI":"10.1378\/chest.109.5.1370"},{"key":"2024102022372319000_43.6.1573.7","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.97.10112612"},{"key":"2024102022372319000_43.6.1573.8","doi-asserted-by":"publisher","DOI":"10.1067\/mai.2003.1374"},{"key":"2024102022372319000_43.6.1573.9","doi-asserted-by":"publisher","DOI":"10.1097\/00130832-200304000-00003"},{"key":"2024102022372319000_43.6.1573.10","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200311-1575SO"},{"key":"2024102022372319000_43.6.1573.11","doi-asserted-by":"crossref","unstructured":"Vandenplas O Cartier A Malo JL . Occupational challenge tests. In: Bernstein IL Chan-Yeung M Malo JL , eds. Asthma in the Workplace. 3rd Edn. New York, Taylor and Francis, 2006; pp. 227\u2013252.","DOI":"10.3109\/9780849374531-11"},{"key":"2024102022372319000_43.6.1573.12","doi-asserted-by":"publisher","DOI":"10.1016\/0091-6749(89)90346-1"},{"key":"2024102022372319000_43.6.1573.13","doi-asserted-by":"publisher","DOI":"10.1183\/09041950.053s1693"},{"key":"2024102022372319000_43.6.1573.14","doi-asserted-by":"publisher","DOI":"10.1378\/chest.06-0492"},{"key":"2024102022372319000_43.6.1573.15","doi-asserted-by":"publisher","DOI":"10.1378\/chest.121.4.1323"},{"key":"2024102022372319000_43.6.1573.16","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmed.2007.04.014"},{"key":"2024102022372319000_43.6.1573.17","doi-asserted-by":"publisher","DOI":"10.1378\/chest.06-2487"},{"key":"2024102022372319000_43.6.1573.18","doi-asserted-by":"publisher","DOI":"10.1093\/occmed\/kqm090"},{"key":"2024102022372319000_43.6.1573.19","doi-asserted-by":"crossref","unstructured":"Suojalehto H Cullinan P . Specific inhalation challenge tests for occupational asthma in Europe: a survey. Eur Respir Rev 2014; [in press, DOI: 10.1183\/09059180.00000414].","DOI":"10.1183\/09059180.00000414"},{"key":"2024102022372319000_43.6.1573.20","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.167.5.787"},{"key":"2024102022372319000_43.6.1573.21","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2466-9-7"},{"key":"2024102022372319000_43.6.1573.22","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.812011ST"},{"key":"2024102022372319000_43.6.1573.23","doi-asserted-by":"publisher","DOI":"10.1378\/chest.118.5.1309"},{"key":"2024102022372319000_43.6.1573.24","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.03.00053203"},{"key":"2024102022372319000_43.6.1573.25","doi-asserted-by":"publisher","DOI":"10.1183\/09059180.00004911"},{"key":"2024102022372319000_43.6.1573.26","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.161.1.ats11-99"},{"key":"2024102022372319000_43.6.1573.27","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00138707"},{"key":"2024102022372319000_43.6.1573.28","doi-asserted-by":"publisher","DOI":"10.1097\/ACI.0b013e328355b7e4"},{"key":"2024102022372319000_43.6.1573.29","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1183\/09031936.93.05070887","article-title":"Update on an exposure system for particles in the diagnosis of occupational asthma","volume":"5","author":"Cloutier","year":"1992","journal-title":"Eur Respir J"},{"key":"2024102022372319000_43.6.1573.30","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm\/145.3.582"},{"key":"2024102022372319000_43.6.1573.31","doi-asserted-by":"publisher","DOI":"10.1089\/jam.2000.13.1"},{"key":"2024102022372319000_43.6.1573.32","doi-asserted-by":"publisher","DOI":"10.1186\/1465-9921-11-72"},{"key":"2024102022372319000_43.6.1573.33","first-page":"1","article-title":"EAACI provocation tests with allergens. Report prepared by the European Academy of Allergology and Clinical Immunology Subcommittee on provocation tests with allergens","volume":"52","author":"Melillo","year":"1997","journal-title":"Allergy"},{"key":"2024102022372319000_43.6.1573.34","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2222.1974.tb01358.x"},{"key":"2024102022372319000_43.6.1573.35","doi-asserted-by":"publisher","DOI":"10.1016\/0091-6749(80)90040-8"},{"key":"2024102022372319000_43.6.1573.36","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2222.1982.tb02551.x"},{"key":"2024102022372319000_43.6.1573.37","first-page":"1010","article-title":"Prednisone inhibits late asthmatic reactions and the associated increase in airway responsiveness induced by toluene-diisocyanate in sensitized subjects","volume":"132","author":"Fabbri","year":"1985","journal-title":"Am Rev Respir Dis"},{"key":"2024102022372319000_43.6.1573.38","doi-asserted-by":"publisher","DOI":"10.1016\/0091-6749(87)90028-5"},{"key":"2024102022372319000_43.6.1573.39","doi-asserted-by":"publisher","DOI":"10.1016\/0091-6749(87)90204-1"},{"key":"2024102022372319000_43.6.1573.40","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm\/136.6.1403"},{"key":"2024102022372319000_43.6.1573.41","doi-asserted-by":"publisher","DOI":"10.1016\/0952-0600(88)90005-1"},{"key":"2024102022372319000_43.6.1573.42","doi-asserted-by":"publisher","DOI":"10.1016\/0091-6749(93)90319-B"},{"key":"2024102022372319000_43.6.1573.43","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.149.6.8004297"},{"key":"2024102022372319000_43.6.1573.44","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.154.5.8912734"},{"key":"2024102022372319000_43.6.1573.45","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.159.5.9808123"},{"key":"2024102022372319000_43.6.1573.46","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.162.3.9910077"},{"key":"2024102022372319000_43.6.1573.47","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.164.4.2007063"},{"key":"2024102022372319000_43.6.1573.48","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2004.11.023"},{"key":"2024102022372319000_43.6.1573.49","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmed.2013.01.008"},{"key":"2024102022372319000_43.6.1573.50","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.94.07040806"},{"key":"2024102022372319000_43.6.1573.51","first-page":"89","article-title":"Bronchial inhalation tests. II. Measurement of allergic (and occupational) bronchial responsiveness","volume":"59","author":"Cockcroft","year":"1987","journal-title":"Ann Allergy"},{"key":"2024102022372319000_43.6.1573.52","doi-asserted-by":"publisher","DOI":"10.1016\/0091-6749(92)90303-J"},{"key":"2024102022372319000_43.6.1573.53","doi-asserted-by":"publisher","DOI":"10.1016\/0091-6749(93)90342-D"},{"key":"2024102022372319000_43.6.1573.54","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1183\/09031936.95.08050861","article-title":"Occupational asthma due to formaldehyde resin dust with and without reaction to formaldehyde gas","volume":"8","author":"Lemi\u00e8re","year":"1995","journal-title":"Eur Respir J"},{"key":"2024102022372319000_43.6.1573.55","doi-asserted-by":"crossref","first-page":"1712","DOI":"10.1111\/j.1365-2222.2008.03101.x","article-title":"Allergens to wheat and related cereals","volume":"38","author":"Tatham","year":"2008","journal-title":"Clin Exp Allergy"},{"key":"2024102022372319000_43.6.1573.56","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2222.2009.03342.x"},{"key":"2024102022372319000_43.6.1573.57","doi-asserted-by":"publisher","DOI":"10.1378\/chest.12-1983"},{"key":"2024102022372319000_43.6.1573.58","doi-asserted-by":"publisher","DOI":"10.1016\/0091-6749(91)90381-W"},{"key":"2024102022372319000_43.6.1573.59","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm\/147.5.1287"},{"key":"2024102022372319000_43.6.1573.60","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.98.12040885"},{"key":"2024102022372319000_43.6.1573.61","first-page":"264","article-title":"Prediction of airway responsiveness to allergen from skin sensitivity to allergen and airway responsiveness to histamine","volume":"135","author":"Cockcroft","year":"1987","journal-title":"Am Rev Respir Dis"},{"key":"2024102022372319000_43.6.1573.62","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.2004.00612.x"},{"key":"2024102022372319000_43.6.1573.63","first-page":"267","article-title":"Nonallergic airway hyperresponsiveness and allergen-specific IgE levels are the main determinants of the early and late asthmatic response to allergen","volume":"23","author":"Barnig","year":"2013","journal-title":"J Investig Allergol Clin Immunol"},{"key":"2024102022372319000_43.6.1573.64","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.2006.01189.x"},{"key":"2024102022372319000_43.6.1573.65","first-page":"374","article-title":"Measurement of responsiveness to inhaled histamine: comparison of FEV1 and S Gaw","volume":"51","author":"Cockcroft","year":"1983","journal-title":"Ann Allergy"},{"key":"2024102022372319000_43.6.1573.66","doi-asserted-by":"publisher","DOI":"10.1067\/mai.2000.106548"},{"key":"2024102022372319000_43.6.1573.67","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.2008.01783.x"},{"key":"2024102022372319000_43.6.1573.68","doi-asserted-by":"publisher","DOI":"10.1183\/09041950.005s1693"},{"key":"2024102022372319000_43.6.1573.69","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.05.00034805"},{"key":"2024102022372319000_43.6.1573.70","doi-asserted-by":"publisher","DOI":"10.1034\/j.1398-9995.1999.t01-1-00105.x"},{"key":"2024102022372319000_43.6.1573.71","doi-asserted-by":"publisher","DOI":"10.3109\/02770900903229677"},{"key":"2024102022372319000_43.6.1573.72","doi-asserted-by":"publisher","DOI":"10.1016\/0091-6749(79)90019-8"},{"key":"2024102022372319000_43.6.1573.73","doi-asserted-by":"publisher","DOI":"10.1136\/thx.38.7.516"},{"key":"2024102022372319000_43.6.1573.74","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2222.1987.tb02006.x"},{"key":"2024102022372319000_43.6.1573.75","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.03.00089403"},{"key":"2024102022372319000_43.6.1573.76","doi-asserted-by":"publisher","DOI":"10.1046\/j.1398-9995.2003.00313.x"},{"key":"2024102022372319000_43.6.1573.77","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2222.2012.03970.x"},{"key":"2024102022372319000_43.6.1573.78","doi-asserted-by":"publisher","DOI":"10.1046\/j.1398-9995.2003.00375.x"},{"key":"2024102022372319000_43.6.1573.79","doi-asserted-by":"publisher","DOI":"10.1136\/thx.51.5.472"},{"key":"2024102022372319000_43.6.1573.80","doi-asserted-by":"publisher","DOI":"10.1378\/chest.123.4.1276"},{"key":"2024102022372319000_43.6.1573.81","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.2008.01896.x"},{"key":"2024102022372319000_43.6.1573.82","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1155\/1999\/858549","article-title":"Occupational neutrophilic asthma","volume":"6","author":"Leigh","year":"1999","journal-title":"Can Respir J"},{"key":"2024102022372319000_43.6.1573.83","doi-asserted-by":"publisher","DOI":"10.1067\/mai.2002.128806"},{"key":"2024102022372319000_43.6.1573.84","doi-asserted-by":"publisher","DOI":"10.3109\/15563650.2011.590141"},{"key":"2024102022372319000_43.6.1573.85","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.2009.02274.x"},{"key":"2024102022372319000_43.6.1573.86","doi-asserted-by":"publisher","DOI":"10.1002\/ajim.20948"},{"key":"2024102022372319000_43.6.1573.87","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.99.13348999"},{"key":"2024102022372319000_43.6.1573.88","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.02.00041802"},{"key":"2024102022372319000_43.6.1573.89","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.05.00021504"},{"key":"2024102022372319000_43.6.1573.90","doi-asserted-by":"crossref","unstructured":"Barbinova L Baur X . Increase in exhaled nitric oxide (eNO) after work-related isocyanate exposure. Int Arch Occup Environ Health;2006: 1\u20139.","DOI":"10.1007\/s00420-005-0051-x"},{"key":"2024102022372319000_43.6.1573.91","doi-asserted-by":"publisher","DOI":"10.2478\/v10001-008-0024-x"},{"key":"2024102022372319000_43.6.1573.92","doi-asserted-by":"publisher","DOI":"10.1378\/chest.08-2338"},{"key":"2024102022372319000_43.6.1573.93","doi-asserted-by":"publisher","DOI":"10.1007\/s00408-011-9358-4"},{"key":"2024102022372319000_43.6.1573.94","first-page":"421","article-title":"Changes in exhaled nitric oxide after inhalation challenge with occupational agents","volume":"23","author":"Sastre","year":"2013","journal-title":"J Invest Allergol Clin Immunol"},{"key":"2024102022372319000_43.6.1573.95","doi-asserted-by":"crossref","unstructured":"Walters GI Moore V Mc Grath EE . Fractional exhaled nitric oxide in the interpretation of specific inhalational challenge tests for occupational asthma. Lung 2013 [in press, DOI: 10.1007\/s00408-013-9531-z].","DOI":"10.1007\/s00408-013-9531-z"},{"key":"2024102022372319000_43.6.1573.96","doi-asserted-by":"publisher","DOI":"10.1378\/chest.09-2081"},{"key":"2024102022372319000_43.6.1573.97","doi-asserted-by":"publisher","DOI":"10.1136\/thx.35.6.415"},{"key":"2024102022372319000_43.6.1573.98","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.158.3.9710036"},{"key":"2024102022372319000_43.6.1573.99","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0b013e31816d1dda"},{"key":"2024102022372319000_43.6.1573.100","doi-asserted-by":"publisher","DOI":"10.2500\/ajr.2007.21.3039"},{"key":"2024102022372319000_43.6.1573.101","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.2008.01801.x"},{"key":"2024102022372319000_43.6.1573.102","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1007\/s00420-009-0459-9","article-title":"Nasal blown secretion evaluation in specific occupational nasal challenges","volume":"83","author":"Pignatti","year":"2009","journal-title":"Int Arch Occup Environ Health"},{"key":"2024102022372319000_43.6.1573.103","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1111\/j.1398-9995.2009.02288.x","article-title":"Clinical and inflammatory features of occupational asthma caused by persulphate salts in comparison with asthma associated with occupational rhinitis","volume":"65","author":"Moscato","year":"2010","journal-title":"Allergy"},{"key":"2024102022372319000_43.6.1573.104","doi-asserted-by":"publisher","DOI":"10.1378\/chest.08-0778"},{"key":"2024102022372319000_43.6.1573.105","doi-asserted-by":"publisher","DOI":"10.1136\/thx.2009.120923"},{"key":"2024102022372319000_43.6.1573.106","doi-asserted-by":"publisher","DOI":"10.1093\/occmed\/kqr023"},{"key":"2024102022372319000_43.6.1573.107","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0274(199802)33:2<114::AID-AJIM3>3.0.CO;2-Y"},{"key":"2024102022372319000_43.6.1573.108","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.9120-11ST"},{"key":"2024102022372319000_43.6.1573.109","first-page":"494","article-title":"Nonasthmatic eosinophilic bronchitis in a baker caused by fungal alpha-amylase and wheat flour","volume":"18","author":"Barranco","year":"2008","journal-title":"J Investig Allergol Clin Immunol"},{"key":"2024102022372319000_43.6.1573.110","doi-asserted-by":"publisher","DOI":"10.1136\/thx.2005.045666"},{"key":"2024102022372319000_43.6.1573.111","doi-asserted-by":"crossref","first-page":"1542","DOI":"10.1111\/j.1398-9995.2005.00920.x","article-title":"Occupational eosinophilic bronchitis","volume":"60","author":"Yacoub","year":"2005","journal-title":"Allergy"},{"key":"2024102022372319000_43.6.1573.112","doi-asserted-by":"publisher","DOI":"10.1093\/occmed\/kqi054"},{"key":"2024102022372319000_43.6.1573.113","doi-asserted-by":"publisher","DOI":"10.1097\/00130832-200404000-00003"},{"key":"2024102022372319000_43.6.1573.114","doi-asserted-by":"publisher","DOI":"10.1067\/mai.2001.116120"},{"key":"2024102022372319000_43.6.1573.115","doi-asserted-by":"publisher","DOI":"10.1016\/0954-6111(95)90251-1"},{"key":"2024102022372319000_43.6.1573.116","doi-asserted-by":"publisher","DOI":"10.1016\/0091-6749(90)90065-C"},{"key":"2024102022372319000_43.6.1573.117","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00120407"},{"key":"2024102022372319000_43.6.1573.118","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm\/137.6.1326"},{"key":"2024102022372319000_43.6.1573.119","doi-asserted-by":"publisher","DOI":"10.1378\/chest.103.4.1123"},{"key":"2024102022372319000_43.6.1573.120","doi-asserted-by":"publisher","DOI":"10.1007\/s00420-006-0134-3"},{"key":"2024102022372319000_43.6.1573.121","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.150.4.7921450"},{"key":"2024102022372319000_43.6.1573.122","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.154.2.8756802"},{"key":"2024102022372319000_43.6.1573.123","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.162.3.9910031"},{"key":"2024102022372319000_43.6.1573.124","doi-asserted-by":"crossref","unstructured":"Bernstein IL Chan-Yeung M Malo JL . Definition and classification of asthma in the workplace. In: Bernstein IL Chan-Yeung M Malo JL , eds. Asthma in the Workplace. 3rd Edn. New York, Marcel Dekker Inc., 2006; pp. 1\u20138.","DOI":"10.3109\/9780849374531"},{"key":"2024102022372319000_43.6.1573.125","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.293.6542.310"},{"key":"2024102022372319000_43.6.1573.126","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.1164\/arrd.1987.135.6.1261","article-title":"Acute response to 3.0 ppm formaldehyde in exercising healthy nonsmokers and asthmatics","volume":"135","author":"Green","year":"1987","journal-title":"Am Rev Respir Dis"},{"key":"2024102022372319000_43.6.1573.127","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1183\/09031936.93.01060540","article-title":"Acute exposure to sawdust does not alter airway calibre and responsiveness to histamine in asthmatic subjects","volume":"1","author":"De Luca","year":"1988","journal-title":"Eur Respir J"},{"key":"2024102022372319000_43.6.1573.128","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm\/143.4_Pt_1.751"},{"key":"2024102022372319000_43.6.1573.129","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1183\/09031936.97.10030563","article-title":"The effects on asthmatics of exposure to a conventional water-based and a volatile organic compound-free paint","volume":"10","author":"Beach","year":"1997","journal-title":"Eur Respir J"},{"key":"2024102022372319000_43.6.1573.130","doi-asserted-by":"publisher","DOI":"10.1034\/j.1399-3003.1999.13e34.x"},{"key":"2024102022372319000_43.6.1573.131","doi-asserted-by":"publisher","DOI":"10.1136\/oem.56.8.544"},{"key":"2024102022372319000_43.6.1573.132","doi-asserted-by":"publisher","DOI":"10.1378\/chest.109.2.331"},{"key":"2024102022372319000_43.6.1573.133","doi-asserted-by":"publisher","DOI":"10.1002\/ajim.20912"},{"key":"2024102022372319000_43.6.1573.134","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2222.1984.tb02191.x"},{"key":"2024102022372319000_43.6.1573.135","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.96.09030517"},{"key":"2024102022372319000_43.6.1573.136","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1963.01590200076015"},{"key":"2024102022372319000_43.6.1573.137","doi-asserted-by":"publisher","DOI":"10.1016\/0091-6749(86)90179-X"},{"key":"2024102022372319000_43.6.1573.138","doi-asserted-by":"publisher","DOI":"10.1002\/ajim.4700210210"},{"key":"2024102022372319000_43.6.1573.139","doi-asserted-by":"publisher","DOI":"10.1093\/occmed\/kql025"},{"key":"2024102022372319000_43.6.1573.140","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.2008.01465.x"},{"key":"2024102022372319000_43.6.1573.141","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1155\/2007\/206519","article-title":"Cost-effectiveness of various diagnostic approaches for occupational asthma","volume":"14","author":"Kennedy","year":"2007","journal-title":"Can Respir J"}],"container-title":["European Respiratory Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1183\/09031936.00180313","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,24]],"date-time":"2025-02-24T06:48:35Z","timestamp":1740379715000},"score":1,"resource":{"primary":{"URL":"https:\/\/publications.ersnet.org\/lookup\/doi\/10.1183\/09031936.00180313"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,3,6]]},"references-count":141,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2014,5,31]]},"published-print":{"date-parts":[[2014,6]]}},"alternative-id":["10.1183\/09031936.00180313"],"URL":"https:\/\/doi.org\/10.1183\/09031936.00180313","relation":{},"ISSN":["0903-1936","1399-3003"],"issn-type":[{"value":"0903-1936","type":"print"},{"value":"1399-3003","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,3,6]]}}}