{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,10]],"date-time":"2026-01-10T01:43:23Z","timestamp":1768009403181,"version":"3.49.0"},"reference-count":32,"publisher":"European Respiratory Society (ERS)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur Respir J"],"accepted":{"date-parts":[[2009,8,24]]},"published-print":{"date-parts":[[2010,2]]},"abstract":"<jats:p>The aim of the study was to determine whether the Borg dyspnoea scale could be a useful and simple marker to predict respiratory muscle weakness in amyotrophic lateral sclerosis (ALS).<\/jats:p><jats:p>From April 1997 to 2001, respiratory function was perfomed in 72 patients together with the Borg score in both the upright (uBorg) and supine (sBorg) positions.<\/jats:p><jats:p>Mean upright vital capacity (VC) was 81\u00b124% predicted, sniff nasal inspiratory pressure (SNIP) was 55\u00b126% pred, maximal inspiratory pressure (<jats:italic>P<\/jats:italic><jats:sub>I,max<\/jats:sub>) was 57\u00b126% pred and arterial carbon dioxide tension (<jats:italic>P<\/jats:italic><jats:sub>a,CO<jats:sub>2<\/jats:sub><\/jats:sub>) was 41\u00b16\u2005mmHg. The mean Borg scores in the upright and supine positions were 1.7\u00b11.5 and 2.2\u00b12, respectively. A significant relationship between SNIP and uBorg (r\u200a=\u200a0.4; p\u200a=\u200a0.0007) and SNIP and sBorg (r\u200a=\u200a0.58; p&lt;0.0001) was observed. Upright VC, \u0394VC (measured as the supine fall in VC as a percentage of seated VC),<jats:italic>P<\/jats:italic><jats:sub>I,max<\/jats:sub>and<jats:italic>P<\/jats:italic><jats:sub>a,CO<jats:sub>2<\/jats:sub><\/jats:sub>were significantly correlated with SNIP. A cut-off value of 3 on the sBorg scale provided the best sensitivity (80%) and specificity (78%) (area under the curve 0.8) to predict a SNIP \u226440\u2005cmH<jats:sub>2<\/jats:sub>O, indicating severe inspiratory muscle weakness. Patients with a sBorg score \u22653 also exhibited significantly lower VC,<jats:italic>P<\/jats:italic><jats:sub>I,max<\/jats:sub>and twitch mouth pressure during cervical magnetic stimulation, and slightly higher<jats:italic>P<\/jats:italic><jats:sub>a,CO<jats:sub>2<\/jats:sub><\/jats:sub>(43.7\u00b17<jats:italic>versus<\/jats:italic>39.2\u00b15\u2005mmHg; p\u200a=\u200a0.05).<\/jats:p><jats:p>The Borg dyspnoea scale is a valuable noninvasive test for the prediction of inspiratory muscle weakness in ALS patients.<\/jats:p>","DOI":"10.1183\/09031936.00184908","type":"journal-article","created":{"date-parts":[[2009,9,10]],"date-time":"2009-09-10T00:56:09Z","timestamp":1252544169000},"page":"353-360","source":"Crossref","is-referenced-by-count":49,"title":["The Borg dyspnoea score: a relevant clinical marker of inspiratory muscle weakness in amyotrophic lateral sclerosis"],"prefix":"10.1183","volume":"35","author":[{"given":"N.","family":"Just","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.","family":"Bautin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V.","family":"Danel-Brunaud","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V.","family":"Debroucker","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Matran","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Perez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"81","published-online":{"date-parts":[[2009,9,9]]},"reference":[{"key":"2024102020033098000_35.2.353.1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/118.3.707"},{"key":"2024102020033098000_35.2.353.2","first-page":"66","volume":"50","year":"1998","journal-title":"Neurology"},{"key":"2024102020033098000_35.2.353.3","doi-asserted-by":"publisher","DOI":"10.1378\/chest.121.2.436"},{"key":"2024102020033098000_35.2.353.4","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1212\/WNL.57.2.357","volume":"57","year":"2001","journal-title":"Neurology"},{"key":"2024102020033098000_35.2.353.5","doi-asserted-by":"crossref","first-page":"1311","DOI":"10.1212\/WNL.52.7.1311","volume":"52","year":"1999","journal-title":"Neurology"},{"key":"2024102020033098000_35.2.353.6","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1979.00500380044004"},{"key":"2024102020033098000_35.2.353.7","doi-asserted-by":"publisher","DOI":"10.1378\/chest.103.2.508"},{"key":"2024102020033098000_35.2.353.8","first-page":"641","volume":"103","year":"1971","journal-title":"Am Rev Respir Dis"},{"key":"2024102020033098000_35.2.353.9","doi-asserted-by":"publisher","DOI":"10.1002\/1531-8249(199912)46:6<887::AID-ANA11>3.0.CO;2-L"},{"key":"2024102020033098000_35.2.353.10","doi-asserted-by":"publisher","DOI":"10.1136\/thx.50.4.371"},{"key":"2024102020033098000_35.2.353.11","doi-asserted-by":"publisher","DOI":"10.1034\/j.1399-3003.2000.15b19.x"},{"key":"2024102020033098000_35.2.353.12","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1164\/ajrccm.161.3.9805008","volume":"161","year":"2000","journal-title":"Am J Respir Crit Care Med"},{"key":"2024102020033098000_35.2.353.13","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/124.10.2000"},{"key":"2024102020033098000_35.2.353.14","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200403-314OC"},{"key":"2024102020033098000_35.2.353.15","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(05)70326-4"},{"key":"2024102020033098000_35.2.353.16","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-127-6-199709150-00006"},{"key":"2024102020033098000_35.2.353.17","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-510X(99)00045-3"},{"key":"2024102020033098000_35.2.353.18","doi-asserted-by":"crossref","unstructured":"Pinto AC, Evangelista T, Carvalho M, et al. 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